Click here to switch to the map view.

The map label for this gene is ahpC [H]

Identifier: 212223996

GI number: 212223996

Start: 784305

End: 784874

Strand: Reverse

Name: ahpC [H]

Synonym: TON_0847

Alternate gene names: 212223996

Gene position: 784874-784305 (Counterclockwise)

Preceding gene: 212223998

Following gene: 212223995

Centisome position: 42.48

GC content: 53.68

Gene sequence:

>570_bases
ATGGTGAAAGTTGGAGAAATCGTCCCGGACTTTGAGACAGATGCTTACCTTCCGGAAAAGGACGCAATAGAGAAGGTTAA
GCTTTCGGACTACAGGGGCAAGTGGGTTGTTTTGGCGTTTTATCCGGCTGACTTCACCTTCGTCTGCCCGACGGAGCTTG
AAGAGCTTGCTGAATACTACGAAGAGTTCAAGAAGGAAGGCGCCGAGATCCTGAGCGTTTCAACGGACACTGCCTACGTC
CACAAGGCCTGGCACGACACTTCTCCCGCGATCAAGAAGATAAAGTACCCAATGCTCGCCGACCCAGCGGGAAAGATATG
CCGCCTCTTCGGCACTTACATCGAGGACGAGGGCGTCTCCTGGAGGGCGACCTTTATCATAGACCCTGACGGAAAAGTCG
TCCACATGGAGATGCACGATTTGAGCATAGGCAGGAGCGCGAAGGAGATACTGAGAAGGCTCAGGGCCTCTAAGTATGTG
AGGGAGCACCCTGGACAGGTGTGCCCGGCTAGCTGGGAGCCCGGTAAGGAGACCCTCGAGGTTAGCCTCGATTTAGTTGG
AAAGATTTAA

Upstream 100 bases:

>100_bases
GTCCTCCAAAATGCAATACTTTCGATTTTGGAACTTTTCACTTTGTTAGGCAAACCTATATAAGTTAGGTTTCCCAACAT
AGTCCCGAGGTGTTTGAAAG

Downstream 100 bases:

>100_bases
CCCCCTTTTTCCATTTTGTAAATTTTGAGCCGTTTCTTTCTCACATTAAGCAGGTGACAGACATGGGCATGCCCATACCT
GGGCAGTTATTGCGAATTGT

Product: alkyl hydroperoxide reductase subunit c

Products: NA

Alternate protein names: Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVKVGEIVPDFETDAYLPEKDAIEKVKLSDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEILSVSTDTAYV
HKAWHDTSPAIKKIKYPMLADPAGKICRLFGTYIEDEGVSWRATFIIDPDGKVVHMEMHDLSIGRSAKEILRRLRASKYV
REHPGQVCPASWEPGKETLEVSLDLVGKI

Sequences:

>Translated_189_residues
MVKVGEIVPDFETDAYLPEKDAIEKVKLSDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEILSVSTDTAYV
HKAWHDTSPAIKKIKYPMLADPAGKICRLFGTYIEDEGVSWRATFIIDPDGKVVHMEMHDLSIGRSAKEILRRLRASKYV
REHPGQVCPASWEPGKETLEVSLDLVGKI
>Mature_189_residues
MVKVGEIVPDFETDAYLPEKDAIEKVKLSDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEILSVSTDTAYV
HKAWHDTSPAIKKIKYPMLADPAGKICRLFGTYIEDEGVSWRATFIIDPDGKVVHMEMHDLSIGRSAKEILRRLRASKYV
REHPGQVCPASWEPGKETLEVSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=185, Percent_Identity=42.1621621621622, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI4505591, Length=181, Percent_Identity=39.2265193370166, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI32455266, Length=181, Percent_Identity=39.2265193370166, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI32455264, Length=181, Percent_Identity=39.2265193370166, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI5453549, Length=160, Percent_Identity=41.875, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI32483377, Length=160, Percent_Identity=40, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI5802974, Length=160, Percent_Identity=40, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI33188454, Length=87, Percent_Identity=48.2758620689655, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4758638, Length=194, Percent_Identity=26.2886597938144, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786822, Length=160, Percent_Identity=53.75, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1788825, Length=142, Percent_Identity=30.2816901408451, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204376, Length=180, Percent_Identity=41.6666666666667, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32565831, Length=180, Percent_Identity=41.6666666666667, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17554494, Length=154, Percent_Identity=42.2077922077922, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323613, Length=187, Percent_Identity=36.8983957219251, Blast_Score=132, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320661, Length=161, Percent_Identity=38.5093167701863, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319407, Length=191, Percent_Identity=26.7015706806283, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=38.7434554973822, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI17738015, Length=187, Percent_Identity=40.1069518716578, Blast_Score=156, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24656348, Length=174, Percent_Identity=42.5287356321839, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17864676, Length=174, Percent_Identity=42.5287356321839, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17157991, Length=157, Percent_Identity=42.0382165605096, Blast_Score=143, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24641739, Length=157, Percent_Identity=42.0382165605096, Blast_Score=143, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24652436, Length=190, Percent_Identity=32.6315789473684, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24652434, Length=190, Percent_Identity=32.6315789473684, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17975518, Length=190, Percent_Identity=32.6315789473684, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24581278, Length=188, Percent_Identity=26.5957446808511, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21488; Mature: 21488

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVGEIVPDFETDAYLPEKDAIEKVKLSDYRGKWVVLAFYPADFTFVCPTELEELAEYY
CCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCEEEEEEECCCEEEECHHHHHHHHHHH
EEFKKEGAEILSVSTDTAYVHKAWHDTSPAIKKIKYPMLADPAGKICRLFGTYIEDEGVS
HHHHHCCCEEEEECCCCCEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
WRATFIIDPDGKVVHMEMHDLSIGRSAKEILRRLRASKYVREHPGQVCPASWEPGKETLE
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEE
VSLDLVGKI
EEEEEECCC
>Mature Secondary Structure
MVKVGEIVPDFETDAYLPEKDAIEKVKLSDYRGKWVVLAFYPADFTFVCPTELEELAEYY
CCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCEEEEEEECCCEEEECHHHHHHHHHHH
EEFKKEGAEILSVSTDTAYVHKAWHDTSPAIKKIKYPMLADPAGKICRLFGTYIEDEGVS
HHHHHCCCEEEEECCCCCEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
WRATFIIDPDGKVVHMEMHDLSIGRSAKEILRRLRASKYVREHPGQVCPASWEPGKETLE
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEE
VSLDLVGKI
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA