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The map label for this gene is cobD [H]

Identifier: 212223828

GI number: 212223828

Start: 634097

End: 634981

Strand: Reverse

Name: cobD [H]

Synonym: TON_0679

Alternate gene names: 212223828

Gene position: 634981-634097 (Counterclockwise)

Preceding gene: 212223829

Following gene: 212223827

Centisome position: 34.37

GC content: 52.77

Gene sequence:

>885_bases
ATGGAAGCTTTAGTAACTTTTGTGGTTGCGCTCCTCTGGGATTTCCTCCTCGGCGAACCGCCAGCATTAGTCCATCCCAC
CGTCTGGTTCGGCAGGCTAATCGGTCTCTTTGATGGGATATACAGAAGAAGAAGCTCGATTTTGGACTTTCTCGCCGGAA
CCTCTGCTTCTCTCTTTGTCATCACCTTCGCCTTTGCCCTCTCCAAGCTTCCGGAGCTTCTGCCAGAGTGGCTGGGTTTC
GCCCTGGGCGTTTACCTTCTAAAAAGCTCCTTCGCGATTAAAAGCCTCGCCCAGCACGTGGAGAACACGGTGAGGGACAA
CATAGAAGAGCAGAGGAAGTACGTGGGCTGGATAGTCAGCAGGGACGTCTCAAAGCTCGATAGGGCTCATCTCAATTCAG
CGGCCATAGAGAGCCTCGCAGAGAACATCACAGACAGCATCGTTGCTCCGCTCTTCTACTATCTCCTCTTCGGCCTGTCA
GGAGCTCTTGTTTACCGTGCTGTGAATACTCTGGACGCCATGATAGGCTACCGCGATGAAAGGCACGAGTATTTTGGCAA
GTTTGCAGCGCGTCTTGACGATTTGCTCAACTTCATCCCAGCCCGCATTACCGTTCTGCTCTTCCTGCCCCTCAGTCCGA
GAAAGGTTCTCGAATACTGGGGGAAGGCGAAGTTTAAGATAAATGCCGACAAGCCCATAGCAGCTATGAGCGCCGTCCTC
GGAGTATGGCTTAAGAAAGAAGGGGTCTATCACTTTGAAGGCAGGGAGCCGACGCTCGAAGATATAAGGCGGGCGCTGAG
GATTTATTGGATTGTCGTGGGAGAGTGGATAGCTGTCGTGTTGCTACTGCTCTTAACGGGGGTGTGTCCATGCTTGAACC
CGTGA

Upstream 100 bases:

>100_bases
CTTATTTAAGACACCCCGCTTGGTACGTGCGCAGGGGCTTGAGGGAACCTAACGAGGAGATGCTCAGTGAATACACCCAG
GTAAAGGAGGCCCTCGGAGA

Downstream 100 bases:

>100_bases
GATTCTCAACCTATCACGGAGGGGCGAGGGAAGAGGGTTTGCTCGACTTCTCTGCCTCGCTCAATCCGTATCTGCCAGAG
TGGACCGGTGAGATGTTTGA

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEALVTFVVALLWDFLLGEPPALVHPTVWFGRLIGLFDGIYRRRSSILDFLAGTSASLFVITFAFALSKLPELLPEWLGF
ALGVYLLKSSFAIKSLAQHVENTVRDNIEEQRKYVGWIVSRDVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLS
GALVYRAVNTLDAMIGYRDERHEYFGKFAARLDDLLNFIPARITVLLFLPLSPRKVLEYWGKAKFKINADKPIAAMSAVL
GVWLKKEGVYHFEGREPTLEDIRRALRIYWIVVGEWIAVVLLLLLTGVCPCLNP

Sequences:

>Translated_294_residues
MEALVTFVVALLWDFLLGEPPALVHPTVWFGRLIGLFDGIYRRRSSILDFLAGTSASLFVITFAFALSKLPELLPEWLGF
ALGVYLLKSSFAIKSLAQHVENTVRDNIEEQRKYVGWIVSRDVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLS
GALVYRAVNTLDAMIGYRDERHEYFGKFAARLDDLLNFIPARITVLLFLPLSPRKVLEYWGKAKFKINADKPIAAMSAVL
GVWLKKEGVYHFEGREPTLEDIRRALRIYWIVVGEWIAVVLLLLLTGVCPCLNP
>Mature_294_residues
MEALVTFVVALLWDFLLGEPPALVHPTVWFGRLIGLFDGIYRRRSSILDFLAGTSASLFVITFAFALSKLPELLPEWLGF
ALGVYLLKSSFAIKSLAQHVENTVRDNIEEQRKYVGWIVSRDVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLS
GALVYRAVNTLDAMIGYRDERHEYFGKFAARLDDLLNFIPARITVLLFLPLSPRKVLEYWGKAKFKINADKPIAAMSAVL
GVWLKKEGVYHFEGREPTLEDIRRALRIYWIVVGEWIAVVLLLLLTGVCPCLNP

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 33206; Mature: 33206

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALVTFVVALLWDFLLGEPPALVHPTVWFGRLIGLFDGIYRRRSSILDFLAGTSASLFV
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITFAFALSKLPELLPEWLGFALGVYLLKSSFAIKSLAQHVENTVRDNIEEQRKYVGWIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLSGALVYRAVNTLDAMIGYRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RHEYFGKFAARLDDLLNFIPARITVLLFLPLSPRKVLEYWGKAKFKINADKPIAAMSAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHH
GVWLKKEGVYHFEGREPTLEDIRRALRIYWIVVGEWIAVVLLLLLTGVCPCLNP
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEALVTFVVALLWDFLLGEPPALVHPTVWFGRLIGLFDGIYRRRSSILDFLAGTSASLFV
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITFAFALSKLPELLPEWLGFALGVYLLKSSFAIKSLAQHVENTVRDNIEEQRKYVGWIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLSGALVYRAVNTLDAMIGYRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RHEYFGKFAARLDDLLNFIPARITVLLFLPLSPRKVLEYWGKAKFKINADKPIAAMSAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHH
GVWLKKEGVYHFEGREPTLEDIRRALRIYWIVVGEWIAVVLLLLLTGVCPCLNP
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA