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The map label for this gene is hisC2 [H]

Identifier: 212223827

GI number: 212223827

Start: 633150

End: 634112

Strand: Reverse

Name: hisC2 [H]

Synonym: TON_0678

Alternate gene names: 212223827

Gene position: 634112-633150 (Counterclockwise)

Preceding gene: 212223828

Following gene: 212223825

Centisome position: 34.32

GC content: 54.52

Gene sequence:

>963_bases
ATGCTTGAACCCGTGAGATTCTCAACCTATCACGGAGGGGCGAGGGAAGAGGGTTTGCTCGACTTCTCTGCCTCGCTCAA
TCCGTATCTGCCAGAGTGGACCGGTGAGATGTTTGAAAGGGCGAAATCTATCAGCAATAGGTACCCATACTACAGGGGGC
TTGAGGAGGAGCTTTCCAAACTCGTCGGAAAACCCGTCACGGTTACGGCAGGCATAACCGAGGCCCTTTACCTCATCGGA
ATCCTCGCGCTAAAGGGAAGGAAGGTCATCATCCCGCGCCACACCTACGGGGAATACGAGAGGGTGACGAAAATCTTCGG
GGCCGAGGTCATACCAGGCCCAAACGATCCAGAGAAGCTCGCCGAACTCGTAGAGAACGAGAGTATCGTTTTCTTCTGCA
ACCCCAACAACCCCGACGGCAAGTTCTACTCGCCAAAGGGGCTCAGGCCTCTTCTCGATGCCGTCGAAGACAAAGGCGCG
CTCCTTATACTTGATGAGGCATTCATAGACTTCGTCAAAGGAGCGAAAAGTCCAGAAGGGGAAAACCTCGTGAAGCTCAG
GACCTTCACCAAGAGCTACGGGCTGCCCGGGATAAGGGTGGGCTACGTCATCGGCTTTGAGGAGGCCTTTAAAAGCGTCC
GCATGCCCTGGAGTATAGGCTCGCTCGGCTACGCCTTTTTGGAGTTCCTCATCGAGGACGGCTTCGAGCATCTCAAGAAA
ACGATGCCTCTAATCTGGCGCGAGAAGGAGCGGATGGAAAAGGCCCTGGACATCAAAAGCGATGCCAACTTCTTCATCAA
GCGTGTTGGGGATGCAAAGGCGGTCGTTGAAGCGCTCAAACGTAAAGGAATAGCCGTCCGCGACTGCACGAGCTTTGGTT
TGCCTCAGTACGTCCGCTTCAGCGTGAGGAAGAGGGAGGAGAATGAGAGGCTTATTGAGGCATTCAGGGAGCTTGGCCTT
TGA

Upstream 100 bases:

>100_bases
CGACGCTCGAAGATATAAGGCGGGCGCTGAGGATTTATTGGATTGTCGTGGGAGAGTGGATAGCTGTCGTGTTGCTACTG
CTCTTAACGGGGGTGTGTCC

Downstream 100 bases:

>100_bases
TTCCAACGAGCCAGAGTCTCCACGCATTCGCCGGAAGCTCTCTGAAAGTCGCCATAAATTCTAACCTCGTCGAAGTGCTT
CTCAGCAAGCAGGCGCATTT

Product: putative aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLEPVRFSTYHGGAREEGLLDFSASLNPYLPEWTGEMFERAKSISNRYPYYRGLEEELSKLVGKPVTVTAGITEALYLIG
ILALKGRKVIIPRHTYGEYERVTKIFGAEVIPGPNDPEKLAELVENESIVFFCNPNNPDGKFYSPKGLRPLLDAVEDKGA
LLILDEAFIDFVKGAKSPEGENLVKLRTFTKSYGLPGIRVGYVIGFEEAFKSVRMPWSIGSLGYAFLEFLIEDGFEHLKK
TMPLIWREKERMEKALDIKSDANFFIKRVGDAKAVVEALKRKGIAVRDCTSFGLPQYVRFSVRKREENERLIEAFRELGL

Sequences:

>Translated_320_residues
MLEPVRFSTYHGGAREEGLLDFSASLNPYLPEWTGEMFERAKSISNRYPYYRGLEEELSKLVGKPVTVTAGITEALYLIG
ILALKGRKVIIPRHTYGEYERVTKIFGAEVIPGPNDPEKLAELVENESIVFFCNPNNPDGKFYSPKGLRPLLDAVEDKGA
LLILDEAFIDFVKGAKSPEGENLVKLRTFTKSYGLPGIRVGYVIGFEEAFKSVRMPWSIGSLGYAFLEFLIEDGFEHLKK
TMPLIWREKERMEKALDIKSDANFFIKRVGDAKAVVEALKRKGIAVRDCTSFGLPQYVRFSVRKREENERLIEAFRELGL
>Mature_320_residues
MLEPVRFSTYHGGAREEGLLDFSASLNPYLPEWTGEMFERAKSISNRYPYYRGLEEELSKLVGKPVTVTAGITEALYLIG
ILALKGRKVIIPRHTYGEYERVTKIFGAEVIPGPNDPEKLAELVENESIVFFCNPNNPDGKFYSPKGLRPLLDAVEDKGA
LLILDEAFIDFVKGAKSPEGENLVKLRTFTKSYGLPGIRVGYVIGFEEAFKSVRMPWSIGSLGYAFLEFLIEDGFEHLKK
TMPLIWREKERMEKALDIKSDANFFIKRVGDAKAVVEALKRKGIAVRDCTSFGLPQYVRFSVRKREENERLIEAFRELGL

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=340, Percent_Identity=27.0588235294118, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322075, Length=266, Percent_Identity=27.4436090225564, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 36261; Mature: 36261

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEPVRFSTYHGGAREEGLLDFSASLNPYLPEWTGEMFERAKSISNRYPYYRGLEEELSK
CCCCCEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVGKPVTVTAGITEALYLIGILALKGRKVIIPRHTYGEYERVTKIFGAEVIPGPNDPEKL
HHCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHH
AELVENESIVFFCNPNNPDGKFYSPKGLRPLLDAVEDKGALLILDEAFIDFVKGAKSPEG
HHHHCCCCEEEEECCCCCCCCEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCC
ENLVKLRTFTKSYGLPGIRVGYVIGFEEAFKSVRMPWSIGSLGYAFLEFLIEDGFEHLKK
CCEEEEEEHHHHCCCCCEEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TMPLIWREKERMEKALDIKSDANFFIKRVGDAKAVVEALKRKGIAVRDCTSFGLPQYVRF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEECHHHCCCHHHHHH
SVRKREENERLIEAFRELGL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEPVRFSTYHGGAREEGLLDFSASLNPYLPEWTGEMFERAKSISNRYPYYRGLEEELSK
CCCCCEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVGKPVTVTAGITEALYLIGILALKGRKVIIPRHTYGEYERVTKIFGAEVIPGPNDPEKL
HHCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHH
AELVENESIVFFCNPNNPDGKFYSPKGLRPLLDAVEDKGALLILDEAFIDFVKGAKSPEG
HHHHCCCCEEEEECCCCCCCCEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCC
ENLVKLRTFTKSYGLPGIRVGYVIGFEEAFKSVRMPWSIGSLGYAFLEFLIEDGFEHLKK
CCEEEEEEHHHHCCCCCEEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TMPLIWREKERMEKALDIKSDANFFIKRVGDAKAVVEALKRKGIAVRDCTSFGLPQYVRF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEECHHHCCCHHHHHH
SVRKREENERLIEAFRELGL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]