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The map label for this gene is rfk [H]

Identifier: 212223705

GI number: 212223705

Start: 512176

End: 512811

Strand: Reverse

Name: rfk [H]

Synonym: TON_0557

Alternate gene names: 212223705

Gene position: 512811-512176 (Counterclockwise)

Preceding gene: 212223706

Following gene: 212223704

Centisome position: 27.76

GC content: 50.31

Gene sequence:

>636_bases
ATGAAGAGGCTCAAACTGCTCATCCTGCTAGCAAAGAAAGGAGCGATAGGAGAAAAGGTCAAAATAACTCTAAGAGAGCT
TGCAAACGAGCTTGGTGTATCACCCCAGTCGGTTCTAAGATTGCTCGATGAAATGGAGGAGGAAGGACTCATATCGAAAG
ACGTTAAGGGAAGAAAGACATACGTGGAAATAAGCCAGGGGGGATTAGCTTTCCTTGAGAATCTTTGCGACGCCATCTCA
GAGGTTCTCTACAACGGGATAATTATCGGAGAGGTCATATCGGGAATCGGTGAGGGAGCCTATTACGTCAGACAGTACTC
CCACCTGATAAGGGAGTACCTCGGCTTTGACCCTTACCCTGGAACGCTGAACGTCAGGGTCCTGTTCCCGAGAACTGTCT
TTGATGCACTCTGCGGGGTTAGACCGGTCGTGCTTCCGGGCTTCGCTAAAGATGGGAGGACTTTTGGCGATGTCAAGGCA
TATCGCGTCAGAATCGGCGACGTGGAGGGTGCCATAGTGATACCCTCGAGAACTGTTCATCCACCGAGAATAGCCGAGAT
AATCGCCCCGGTATGCCTCAGGGAGGAGCTCAGCCTTGAAGATGGCTCTAGAATAACCATAAGGGTCGTGAAATGA

Upstream 100 bases:

>100_bases
TCGATTTAGACTCTGCGGCCAGAATAGTTGAGACCCTGCTGGAGCGAGACTATCCAAAACCACTGAGGCTCGCAGACAGA
CTGTCAAAGAGGGGAAGCTT

Downstream 100 bases:

>100_bases
TGAAGGACTGGAAGTCGATCCTGACATGGTCTGGTTTGGGCTCGTTCATCGGATTTGCCATAGCTGTCGCCCTATACTCC
CCAACGGGAAGCGAGAATTT

Product: putative transcription regulator

Products: NA

Alternate protein names: RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKRLKLLILLAKKGAIGEKVKITLRELANELGVSPQSVLRLLDEMEEEGLISKDVKGRKTYVEISQGGLAFLENLCDAIS
EVLYNGIIIGEVISGIGEGAYYVRQYSHLIREYLGFDPYPGTLNVRVLFPRTVFDALCGVRPVVLPGFAKDGRTFGDVKA
YRVRIGDVEGAIVIPSRTVHPPRIAEIIAPVCLREELSLEDGSRITIRVVK

Sequences:

>Translated_211_residues
MKRLKLLILLAKKGAIGEKVKITLRELANELGVSPQSVLRLLDEMEEEGLISKDVKGRKTYVEISQGGLAFLENLCDAIS
EVLYNGIIIGEVISGIGEGAYYVRQYSHLIREYLGFDPYPGTLNVRVLFPRTVFDALCGVRPVVLPGFAKDGRTFGDVKA
YRVRIGDVEGAIVIPSRTVHPPRIAEIIAPVCLREELSLEDGSRITIRVVK
>Mature_211_residues
MKRLKLLILLAKKGAIGEKVKITLRELANELGVSPQSVLRLLDEMEEEGLISKDVKGRKTYVEISQGGLAFLENLCDAIS
EVLYNGIIIGEVISGIGEGAYYVRQYSHLIREYLGFDPYPGTLNVRVLFPRTVFDALCGVRPVVLPGFAKDGRTFGDVKA
YRVRIGDVEGAIVIPSRTVHPPRIAEIIAPVCLREELSLEDGSRITIRVVK

Specific function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) [H]

COG id: COG1339

COG function: function code KH; Transcriptional regulator of a riboflavin/FAD biosynthetic operon

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal riboflavin kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR000835
- InterPro:   IPR015865
- InterPro:   IPR002834
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01982 CTP-dep_RFKase; PF01047 MarR [H]

EC number: =2.7.1.161 [H]

Molecular weight: Translated: 23321; Mature: 23321

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLKLLILLAKKGAIGEKVKITLRELANELGVSPQSVLRLLDEMEEEGLISKDVKGRKT
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
YVEISQGGLAFLENLCDAISEVLYNGIIIGEVISGIGEGAYYVRQYSHLIREYLGFDPYP
EEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GTLNVRVLFPRTVFDALCGVRPVVLPGFAKDGRTFGDVKAYRVRIGDVEGAIVIPSRTVH
CEEEEEEEECHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCC
PPRIAEIIAPVCLREELSLEDGSRITIRVVK
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKRLKLLILLAKKGAIGEKVKITLRELANELGVSPQSVLRLLDEMEEEGLISKDVKGRKT
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
YVEISQGGLAFLENLCDAISEVLYNGIIIGEVISGIGEGAYYVRQYSHLIREYLGFDPYP
EEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GTLNVRVLFPRTVFDALCGVRPVVLPGFAKDGRTFGDVKAYRVRIGDVEGAIVIPSRTVH
CEEEEEEEECHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCC
PPRIAEIIAPVCLREELSLEDGSRITIRVVK
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA