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The map label for this gene is 212223575

Identifier: 212223575

GI number: 212223575

Start: 401281

End: 402369

Strand: Reverse

Name: 212223575

Synonym: TON_0429

Alternate gene names: NA

Gene position: 402369-401281 (Counterclockwise)

Preceding gene: 212223578

Following gene: 212223574

Centisome position: 21.78

GC content: 52.07

Gene sequence:

>1089_bases
ATGAAGGTTCTCGTTCTTGGAGCTGGAAACGTTGGAAGGGCAATAGCCTGGGATTTAAGAGACGAGTTCGAGGTCTGGGT
AGGGGACAGGAGTGAGGAGAGGCTGAACTCCGTTAAAGACTTCGCTGAGACTGTAAAAATAGATGCCTCGAACTTCGATT
CCCTCGTGGAAACCATGAAGAGCTTTGAGCTCGTCGTTGGAGCTCTGCCCGGGAGGTTTGGCTACTCCTCGGTCAAGGCC
GCCATAAAGGCGGGCGTTGACATGGTGGACGTCTCATTCATGCCCGAGAACCCGCTGGAACTACGCGAGGAGGCAGAGAA
AGCACAGGTTACAGTCATTTTTGATGCGGGCTTTGCTCCGGGCTTGAGCCACATACTTATGGGAAGAATATGGCAGGAGA
TAGACGAGCTTAAGGAAGGCTACATCTACGTCGGCGGTCTTCCCAGGGAGCCCCGCCCACCGCTGTATTACAGAATTACA
TGGTCACCTAAAGATCTAATTGAAGAATACACGAGGCCGGCGAGAGTGATAAGAAACGGAAATGTTACGGCAGTTGACCC
GTTCGAGAAGATCGAGAGAGTAACCGTTGGTGACTTCGAGTTTGAGGCTTTCGTGAGCGACGGTCTGCGCTCTTTATTAG
AGAGCGTTAAAGCTGAAAAGCTCGAAGAGTGGACACTCCGCTGGCCGGGACACCTCGAGAAGATGAAAGTTTTAAGGGAG
CTGGGATTCTTCAAGTCGGAGCACATAGACAAGACACTGGAAGTTATAACTCCCCTGATGACCTATGAGAGCCCGGACTT
CTCGATAATGCAGGTCGTTGGAAGGGGGATCCTCGACGGCAAAAAGAAGGAAATCGGCTACCTCCTCTACGATGAAGAGA
AAGAGGGATTCACGTCCATGGCCAGAGTCACGGGCTTTACCGCTGCGATAGTAGCACGTCTCGTCGCCGAGAAGGGCTGC
ATCTTTGGTGTTATACCTCCGGAGATACTCGGAATGCGCATAGACACCTTTACACGGATCACTGAGGAACTTGCCGAGAG
AGGAATAACGCTGGAGAGGTGGGAGAATGCTCCACCTGGTGATAGCTGA

Upstream 100 bases:

>100_bases
TCCAGTACCTTTTTCCGGAAGGTTGGGAGTCTGATGGGCATCTTAGGAATTAGGAGCAGGGCTTATATATACCTTCGCCA
AGGTTCTCTCCGGTGTTACC

Downstream 100 bases:

>100_bases
CTCCGAGCTGGAGCTGGCTCCAAAGTCGATAGTTGATCACCCAGCGATAGTCAACTACGCCAAGAGGAGGAACAAGAAGC
CAGAGGAAGTACTCCTGGAC

Product: Saccharopine reductase

Products: NA

Alternate protein names: Dehydrogenase; L-Lysine Dehydrogenase; Saccharopine Reductase; Saccharopine Dehydrogenase-Like Protein; Saccharopine Dehydrogenase Family Protein; Saccharopine Dehydrogenase Protein; Saccharopine Dehydrogenase And Related Protein; TrkA-NSaccharopine Dehydrogenase; Oxidoreductase; Saccharopine Dehydrogenase Conjectural; L-Lysine 6-Dehydrogenase; Dehydrogenase Protein; Saccharopine Dehydrogenase/Saccharopine Reductase; Amino Acid Dehydrogenase; Lysine Oxoglutarate Reductase/Saccharopine Dehydrogenase

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKVLVLGAGNVGRAIAWDLRDEFEVWVGDRSEERLNSVKDFAETVKIDASNFDSLVETMKSFELVVGALPGRFGYSSVKA
AIKAGVDMVDVSFMPENPLELREEAEKAQVTVIFDAGFAPGLSHILMGRIWQEIDELKEGYIYVGGLPREPRPPLYYRIT
WSPKDLIEEYTRPARVIRNGNVTAVDPFEKIERVTVGDFEFEAFVSDGLRSLLESVKAEKLEEWTLRWPGHLEKMKVLRE
LGFFKSEHIDKTLEVITPLMTYESPDFSIMQVVGRGILDGKKKEIGYLLYDEEKEGFTSMARVTGFTAAIVARLVAEKGC
IFGVIPPEILGMRIDTFTRITEELAERGITLERWENAPPGDS

Sequences:

>Translated_362_residues
MKVLVLGAGNVGRAIAWDLRDEFEVWVGDRSEERLNSVKDFAETVKIDASNFDSLVETMKSFELVVGALPGRFGYSSVKA
AIKAGVDMVDVSFMPENPLELREEAEKAQVTVIFDAGFAPGLSHILMGRIWQEIDELKEGYIYVGGLPREPRPPLYYRIT
WSPKDLIEEYTRPARVIRNGNVTAVDPFEKIERVTVGDFEFEAFVSDGLRSLLESVKAEKLEEWTLRWPGHLEKMKVLRE
LGFFKSEHIDKTLEVITPLMTYESPDFSIMQVVGRGILDGKKKEIGYLLYDEEKEGFTSMARVTGFTAAIVARLVAEKGC
IFGVIPPEILGMRIDTFTRITEELAERGITLERWENAPPGDS
>Mature_362_residues
MKVLVLGAGNVGRAIAWDLRDEFEVWVGDRSEERLNSVKDFAETVKIDASNFDSLVETMKSFELVVGALPGRFGYSSVKA
AIKAGVDMVDVSFMPENPLELREEAEKAQVTVIFDAGFAPGLSHILMGRIWQEIDELKEGYIYVGGLPREPRPPLYYRIT
WSPKDLIEEYTRPARVIRNGNVTAVDPFEKIERVTVGDFEFEAFVSDGLRSLLESVKAEKLEEWTLRWPGHLEKMKVLRE
LGFFKSEHIDKTLEVITPLMTYESPDFSIMQVVGRGILDGKKKEIGYLLYDEEKEGFTSMARVTGFTAAIVARLVAEKGC
IFGVIPPEILGMRIDTFTRITEELAERGITLERWENAPPGDS

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13027640, Length=271, Percent_Identity=28.0442804428044, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541738, Length=284, Percent_Identity=25.7042253521127, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324378, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40823; Mature: 40823

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVLGAGNVGRAIAWDLRDEFEVWVGDRSEERLNSVKDFAETVKIDASNFDSLVETMK
CEEEEEECCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SFELVVGALPGRFGYSSVKAAIKAGVDMVDVSFMPENPLELREEAEKAQVTVIFDAGFAP
HHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEECCCCC
GLSHILMGRIWQEIDELKEGYIYVGGLPREPRPPLYYRITWSPKDLIEEYTRPARVIRNG
CHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCC
NVTAVDPFEKIERVTVGDFEFEAFVSDGLRSLLESVKAEKLEEWTLRWPGHLEKMKVLRE
CEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGFFKSEHIDKTLEVITPLMTYESPDFSIMQVVGRGILDGKKKEIGYLLYDEEKEGFTSM
HCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHCCCCCCCCCEEEEECCHHHHHHH
ARVTGFTAAIVARLVAEKGCIFGVIPPEILGMRIDTFTRITEELAERGITLERWENAPPG
HHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCC
DS
CC
>Mature Secondary Structure
MKVLVLGAGNVGRAIAWDLRDEFEVWVGDRSEERLNSVKDFAETVKIDASNFDSLVETMK
CEEEEEECCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SFELVVGALPGRFGYSSVKAAIKAGVDMVDVSFMPENPLELREEAEKAQVTVIFDAGFAP
HHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEECCCCC
GLSHILMGRIWQEIDELKEGYIYVGGLPREPRPPLYYRITWSPKDLIEEYTRPARVIRNG
CHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCC
NVTAVDPFEKIERVTVGDFEFEAFVSDGLRSLLESVKAEKLEEWTLRWPGHLEKMKVLRE
CEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGFFKSEHIDKTLEVITPLMTYESPDFSIMQVVGRGILDGKKKEIGYLLYDEEKEGFTSM
HCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHCCCCCCCCCEEEEECCHHHHHHH
ARVTGFTAAIVARLVAEKGCIFGVIPPEILGMRIDTFTRITEELAERGITLERWENAPPG
HHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCC
DS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA