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The map label for this gene is yqhT [H]

Identifier: 212223289

GI number: 212223289

Start: 118962

End: 120032

Strand: Reverse

Name: yqhT [H]

Synonym: TON_0143

Alternate gene names: 212223289

Gene position: 120032-118962 (Counterclockwise)

Preceding gene: 212223293

Following gene: 212223287

Centisome position: 6.5

GC content: 54.53

Gene sequence:

>1071_bases
ATGCGCCTCAACAAGCTCACTTCTCTGCTCAAGGAAAAAGCCTTCGACGGAGCGCTGATAAGCCCGGGGACGAACCTCTA
CTACCTAACGAGCCTGCACATCCACGAAGCGGGAGAGAGACTAACGGTTCTAGCCGTCAATTCGAACGGTGAGTACCACC
TTTTAGCGCCAAGCCTCTACGAGAACGTCATCAGGGATTTCCCTGCTACCTTCTGGCGTGATGGAGAGAATCCCTACGGG
AAGCTCGCCGAAATCCTAAAGGAACTCGACCTATCATCTGGCAGGATCCTTGTGGAGAACACGATGAGGGCAGACTGGCT
GATAGGTATTCTCAAGCTTGGAAGCTTCGAGTTCCATCCGTTAAGCATTCTGATGCGCGAGCTTAGAATGAGAAAAGACG
CTGAGGAAATTAGGCTCATGGAGAAGGCGGCAAAGATCGTCGATGAGGTCTTCGAGGAGATAATCGGCATGGACTTAATC
GGAATGCGCGAGAAAGACCTTGCCCTGAAAATTGAGCTCCTCATAAGGGAGCGCTCCGACGGGATATCCTTCGAGCCAAT
AGTTGCCAGCGGTGAGAATGGGGCAAATCCCCACCACGCGCCCGGCGAGAGGAAACTGGGGGAAGGAGACCTCGTTATCC
TCGACTACGGCGCAAAGTGGGAAGGCTACTGCTCAGACATAACGAGGACCATTGCGTTAGGAAAGCCAGACAAGAAGCTT
CTGGAGATTTATGAGGTCGTCAAAAACGCCCAGGAGGGCGCCTTCCAGACCGTCCGCGAGGGCCTAAAGGCGAAGGAGGT
TGACAAAGCGGCAAGGAACTACATAGCGGAAGCGGGCTATGGCGAGTACTTCACTCACAGAACTGGCCATGGACTTGGCT
TAGACGTCCACGAGGAGCCATACATCGGGCCGGACGGCGAGGTAATCCTCAAGAACGGCATGACCTTCACGATAGAGCCG
GGCATCTACGTGCCGGGCCTGGGGGGAGTTAGAATAGAGGACGATGTGGTCGTTGAGGGCGGAAAGGGAAGAAGGTTGAC
GAAGGCACCGAGGGAGCTGATAATCGTGTGA

Upstream 100 bases:

>100_bases
TCTCCCTTACGGGAACATCCCGCGGGTTTGCCCCGCCTAGTCGGGCGAAGTTCGAGATTAGGTTTTTAAAAGTTGCGGAG
TAGTCGAAGCGGTGAAAACC

Downstream 100 bases:

>100_bases
GCTCCCTCATAAACCCTCAATCTTTCCGTCAAAGTGCACGATTCCCTTGTGTATCGTGAAAGTAACTCTATGTGTTTTGA
TGAACTCTTCGAGGTCCGGG

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRLNKLTSLLKEKAFDGALISPGTNLYYLTSLHIHEAGERLTVLAVNSNGEYHLLAPSLYENVIRDFPATFWRDGENPYG
KLAEILKELDLSSGRILVENTMRADWLIGILKLGSFEFHPLSILMRELRMRKDAEEIRLMEKAAKIVDEVFEEIIGMDLI
GMREKDLALKIELLIRERSDGISFEPIVASGENGANPHHAPGERKLGEGDLVILDYGAKWEGYCSDITRTIALGKPDKKL
LEIYEVVKNAQEGAFQTVREGLKAKEVDKAARNYIAEAGYGEYFTHRTGHGLGLDVHEEPYIGPDGEVILKNGMTFTIEP
GIYVPGLGGVRIEDDVVVEGGKGRRLTKAPRELIIV

Sequences:

>Translated_356_residues
MRLNKLTSLLKEKAFDGALISPGTNLYYLTSLHIHEAGERLTVLAVNSNGEYHLLAPSLYENVIRDFPATFWRDGENPYG
KLAEILKELDLSSGRILVENTMRADWLIGILKLGSFEFHPLSILMRELRMRKDAEEIRLMEKAAKIVDEVFEEIIGMDLI
GMREKDLALKIELLIRERSDGISFEPIVASGENGANPHHAPGERKLGEGDLVILDYGAKWEGYCSDITRTIALGKPDKKL
LEIYEVVKNAQEGAFQTVREGLKAKEVDKAARNYIAEAGYGEYFTHRTGHGLGLDVHEEPYIGPDGEVILKNGMTFTIEP
GIYVPGLGGVRIEDDVVVEGGKGRRLTKAPRELIIV
>Mature_356_residues
MRLNKLTSLLKEKAFDGALISPGTNLYYLTSLHIHEAGERLTVLAVNSNGEYHLLAPSLYENVIRDFPATFWRDGENPYG
KLAEILKELDLSSGRILVENTMRADWLIGILKLGSFEFHPLSILMRELRMRKDAEEIRLMEKAAKIVDEVFEEIIGMDLI
GMREKDLALKIELLIRERSDGISFEPIVASGENGANPHHAPGERKLGEGDLVILDYGAKWEGYCSDITRTIALGKPDKKL
LEIYEVVKNAQEGAFQTVREGLKAKEVDKAARNYIAEAGYGEYFTHRTGHGLGLDVHEEPYIGPDGEVILKNGMTFTIEP
GIYVPGLGGVRIEDDVVVEGGKGRRLTKAPRELIIV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=31.4176245210728, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI93141226, Length=176, Percent_Identity=35.7954545454545, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI264681563, Length=193, Percent_Identity=33.6787564766839, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1788728, Length=239, Percent_Identity=39.3305439330544, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789275, Length=263, Percent_Identity=31.5589353612167, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786364, Length=237, Percent_Identity=26.1603375527426, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=346, Percent_Identity=26.878612716763, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=186, Percent_Identity=32.7956989247312, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71989583, Length=313, Percent_Identity=23.6421725239617, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320922, Length=246, Percent_Identity=27.2357723577236, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=25.7950530035336, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322999, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920384, Length=273, Percent_Identity=28.2051282051282, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357079, Length=299, Percent_Identity=26.4214046822742, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137632, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39714; Mature: 39714

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNKLTSLLKEKAFDGALISPGTNLYYLTSLHIHEAGERLTVLAVNSNGEYHLLAPSLY
CCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEECCCCEEEEEEECCCCCEEEECHHHH
ENVIRDFPATFWRDGENPYGKLAEILKELDLSSGRILVENTMRADWLIGILKLGSFEFHP
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCH
LSILMRELRMRKDAEEIRLMEKAAKIVDEVFEEIIGMDLIGMREKDLALKIELLIRERSD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCC
GISFEPIVASGENGANPHHAPGERKLGEGDLVILDYGAKWEGYCSDITRTIALGKPDKKL
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHH
LEIYEVVKNAQEGAFQTVREGLKAKEVDKAARNYIAEAGYGEYFTHRTGHGLGLDVHEEP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCC
YIGPDGEVILKNGMTFTIEPGIYVPGLGGVRIEDDVVVEGGKGRRLTKAPRELIIV
CCCCCCCEEEECCCEEEECCCEEECCCCCEEECCCEEEECCCCCCCCCCCCCEEEC
>Mature Secondary Structure
MRLNKLTSLLKEKAFDGALISPGTNLYYLTSLHIHEAGERLTVLAVNSNGEYHLLAPSLY
CCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEECCCCEEEEEEECCCCCEEEECHHHH
ENVIRDFPATFWRDGENPYGKLAEILKELDLSSGRILVENTMRADWLIGILKLGSFEFHP
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCH
LSILMRELRMRKDAEEIRLMEKAAKIVDEVFEEIIGMDLIGMREKDLALKIELLIRERSD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCC
GISFEPIVASGENGANPHHAPGERKLGEGDLVILDYGAKWEGYCSDITRTIALGKPDKKL
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHH
LEIYEVVKNAQEGAFQTVREGLKAKEVDKAARNYIAEAGYGEYFTHRTGHGLGLDVHEEP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCC
YIGPDGEVILKNGMTFTIEPGIYVPGLGGVRIEDDVVVEGGKGRRLTKAPRELIIV
CCCCCCCEEEECCCEEEECCCEEECCCCCEEECCCEEEECCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]