Click here to switch to the map view.

The map label for this gene is MCM [H]

Identifier: 212223188

GI number: 212223188

Start: 37451

End: 40924

Strand: Reverse

Name: MCM [H]

Synonym: TON_0043

Alternate gene names: 212223188

Gene position: 40924-37451 (Counterclockwise)

Preceding gene: 212223189

Following gene: 212223187

Centisome position: 2.21

GC content: 51.87

Gene sequence:

>3474_bases
ATGGACAGGGAGGACATGATAGAAAGGTACGCGAGATTTCTGCGTGAGTACGTCGATGACAGCGGTAATGAGGTTTACCT
AAACAAGCTTAAAGACCTGCTAACGGTTACCCCAAGGCGCTCTCTATCGATAGACTGGACTCACCTCAACTCCTTTGACC
CCGAATTGGCGGAAGAACTTCTCAAAAACCCCGAAGATAGCATTTTGGCTGCCGAGGACGCCATCCAGATAGTCCTCCGC
GAGCCTCCCCTTTTGAGGGAGGAGGAGTTCAAGGTTCACGCGAGGTTTTTCAACCTTCCAAGGACGCTCCTCGTTAAAGA
ACTCGGCAGCGAGCACATAAACAGGCTCATACAGGTTGATGGAATCATCACGCGCGTGAGCGAGGTCAAGCCATTCGTTG
AGAAGGCCGTCTTCGTCTGTAAGGACTGCGGCAACGAGATGGTAAGACTGCAGAGGCCCTACGACAACATAGTCAAGCCG
AGCAAGTGTGACGCCTGTGGGTCAAGAAACGTTGAGCTCGACGTCGAGAAGAGCAGGTTCATCAACTTCCAGAGCTTCCG
CCTTCAGGACAGGCCCGAGAGCCTCAAGGGTGGCCAGATGCCGAGATTTATTGACGCAATCCTCCTCGACGACCTCGTTG
ATACCGCCCTGCCAGGCGACAGGGTTCTCGTCACGGGAATACTTCGCGTAATTCTCGAGCAGAAGGATAAGCGGCCGATA
TTCAAGAAGGTTCTCGAGGTCAACCACATCGAGCAGCTCAGTAAGGAGATAGAGGAACTTGAGATTACTCCTGAGGACGA
GCAGAAGATAAGGGAGCTGGCAAAGAGAAAGGACATCGTTGATGCTATTGTCGATTCGATAGCCCCGGCAATCTGGGGAC
ACAAGACCGTGAAGAAGGGCATAGCTTTGGCGCTCTTCGGTGGCGTGCAGCGGGTTCTCCCTGATGGAACTAAGCTGAGA
GGAGAGAGCCACGTTCTACTGGTCGGAGATCCTGGTGTTGCGAAGTGCGTTGATTATGACACCCAGGTTGTTCTGGCCGA
CGGGAGCTTAGGGAAGATAGGTGAGCTTGTGGAGGGGGCAATTAGGAGAGCCAAAAAAGAGGGAACCCTCGGCAGAGTTG
ACGACGGCTTCTACGCTCCAATAGACCTTGAGCTTTACGCTCTAGATGCCAAGACGCTCAAAGTGAAAAAGGTGAAGGCT
AACATAGCCTGGAAGAGAACCGCGCCCGAGAGAATGTTCCTCATAAGGACTGCGAGCGGAAGGGAGATAAGGGTAACACC
GACTCATCCATTCTTTGTCTTTGAGAATGGGCAGTTCAAGACAAGGAAGGCTGAGGAACTAAAAGCGAGCGACTTTATAG
CAGTTCCACGCATCATTCCGGTTGCTGGGAAGCCTACTAGGCTTTGGGACATTGAGATAGAAAAGCCCAAAACTGCCAAG
AGCAGGCTAAAGCTTCCTGAATTTGCTGACGAGGAGTTCTGGTACGTTATCGGCCTACTAGCCGGAGAGGGCTACGCACA
GAACAGAAACGGTAGCGCTACGATATTCTTTACGAACAACGACGAAAAGCTGATTCAAAAAGTCTACGAATACTTCAGAA
AGCTCGACCTTAACCCAACGATTAGAAAGCCTCATAGAGGCAAATCGGCGAAAGAGGTTTACGTGAGCAGCGTTGAGTTC
TTCAGATTGTTTAAACATCTTGGAATCGCGGAGAACTCTTCAAAGAAAAAAGTACCATCCCAGATATTCTCCGCAAGGTT
GGAGGACATCAAGGCGTTCCTTCAGGGTTACTTTGACGCAGAGGGGACAGTTGATAGAGCCAGACCAAAAATCACAGTGG
TTTCAGCATCACTGGAACTCCTGAGAGGTGTCCGGCACCTTCTTTTGAGGTTTGGAATAAAATCACAGCTGCACGCGACA
AGAGGCATAGCCACAAACGGAAAGATGAAGGAGGCAAAAACGTACTACCGCCTGGTCATAACGGGCAAAGATGTCATAAA
GTTCAGAGAGACCATCGGTTTTGGAGTTGAGGAGAAGGCAAAACTCCTCGCAAAGGTTACCAACGGGATAAAACTGAACA
CCAACGTTGATGTTGTTCCGGGCGTCTCGAAGCTGCTCAGAGAACTCCGTGAATCAGCAGGACTAAGACAAAAGGACCTA
GGAATAAACCGCTCCACTTACCTGCACTATGAACGGGGGGATAGGCTGCCCAGCAGGGAAAAGCTCAAAATCGTCGTTGA
AACACTGAAAGAGAAGTCGCCTGATGCCCCCAAAAAGCTCAAAGTACTTGAACTGCTTGCGGACTCCGATATCTTCTGGG
ACAGAGTCGTCGAGGTCAGAGAATACAAGCCAGAGCATCCGTGGGTCTACGACCTCCAGGTGCCGGAGCACCACAACTTC
ATAGCCAACGACATCTTCGTCCACAACAGCCAAATTCTCCGCTATGTTGCCAATTTGGCGCCGAGAGCGATTTATACGAG
TGGGAAGAGCAGCTCTGCCGCCGGTTTGACAGCCGCAGCCGTCCGTGACGAATTTACAGGTTCGTGGGTTCTGGAGGCTG
GTGTTCTGGTTCTCGCCGATGGCGGATTTGCCCTAATTGACGAGTTCGACAAGATGAGCGACCGTGACAGGAGCGCTATA
CATGAGGCACTCGAGCAGCAGACAATCAGCATTTCAAAAGCGGGTATCACAGCGACACTTAACTCCAGAACAACGGTTAT
AGCCGCCGCCAATCCAAAGTATGGCAGATTTAACCGCCACAAGTCCCTTCCGGAGCAGCTAGACCTCCCACCGACTCTGC
TGAGCCGTTTCGACCTTATATTCCTCCTGCTGGACGAGCCGGACGAGAAGATAGACGCATCTATAGCCGAGCACATACTC
AAGGTCAGGAGGGGAGAGGCCGAGGCGGTAACGCCCAAGATACCCTACGACCTGCTCAAGAAGTATATAGCCTACGCGAG
GAAGAACATCCACCCGGTTTTGAGCAAAGAGGCGATGGACGAGATAAAGCGCTACTACGTCCGTATGAGGAAGGGCTTCA
GAAAGAGCGGTGAGGACGAGGGAGTGCAGCCGATTCCAATTACTGCGAGGCAGCTGGAGGCACTCATACGTCTCAGCGAG
GCCCATGCGAGAATGCGCCTGAGCGAGACCGTGACGAGGGAAGACGCCAGAGCGGCGATACAGATAATCGAGGAGATGAT
AAGAAAGATAGCGACCGACGAGGAGGGGACACTGGACGTTTCGATCCTCGAAGTCGGCAAGAGTTCCAAGAAGATAAACA
AGATTGACAAGCTCATAGACATCATCAAGAGCCTTGAGAGTGAGGGTGAGTTCGGCGCACCGGAGGACAAGGTAGTGGAA
GCGGCGAAGCAGGCTGGAATTGGAACGGAGAACGAAGTAAAGAAGCTCATCAACGACCTCAAGAGGGACGCGAGGATATA
CGAACCGAGAGCCGGCTTCTACAGGGTGCTTTGA

Upstream 100 bases:

>100_bases
GGCCGAACAGCCTTGAGTTGCTCTCTAGACTCTCCCCCGAGGAGAGAAGGATATACCTGCAGCTGTCGAAGATTAGGAAC
GAGTGGCTGGGTGAGGGCTG

Downstream 100 bases:

>100_bases
TTTTCTCGATTTTCCCCACGCCAAAAGGTTATAAACGGCTCTGCATACCTTAAGTGGAGGTGAGGAAAGTGAGCGAGAAG
AAGGTTGACTTTTACGATTT

Product: cell division control protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1157; Mature: 1157

Protein sequence:

>1157_residues
MDREDMIERYARFLREYVDDSGNEVYLNKLKDLLTVTPRRSLSIDWTHLNSFDPELAEELLKNPEDSILAAEDAIQIVLR
EPPLLREEEFKVHARFFNLPRTLLVKELGSEHINRLIQVDGIITRVSEVKPFVEKAVFVCKDCGNEMVRLQRPYDNIVKP
SKCDACGSRNVELDVEKSRFINFQSFRLQDRPESLKGGQMPRFIDAILLDDLVDTALPGDRVLVTGILRVILEQKDKRPI
FKKVLEVNHIEQLSKEIEELEITPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHKTVKKGIALALFGGVQRVLPDGTKLR
GESHVLLVGDPGVAKCVDYDTQVVLADGSLGKIGELVEGAIRRAKKEGTLGRVDDGFYAPIDLELYALDAKTLKVKKVKA
NIAWKRTAPERMFLIRTASGREIRVTPTHPFFVFENGQFKTRKAEELKASDFIAVPRIIPVAGKPTRLWDIEIEKPKTAK
SRLKLPEFADEEFWYVIGLLAGEGYAQNRNGSATIFFTNNDEKLIQKVYEYFRKLDLNPTIRKPHRGKSAKEVYVSSVEF
FRLFKHLGIAENSSKKKVPSQIFSARLEDIKAFLQGYFDAEGTVDRARPKITVVSASLELLRGVRHLLLRFGIKSQLHAT
RGIATNGKMKEAKTYYRLVITGKDVIKFRETIGFGVEEKAKLLAKVTNGIKLNTNVDVVPGVSKLLRELRESAGLRQKDL
GINRSTYLHYERGDRLPSREKLKIVVETLKEKSPDAPKKLKVLELLADSDIFWDRVVEVREYKPEHPWVYDLQVPEHHNF
IANDIFVHNSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAI
HEALEQQTISISKAGITATLNSRTTVIAAANPKYGRFNRHKSLPEQLDLPPTLLSRFDLIFLLLDEPDEKIDASIAEHIL
KVRRGEAEAVTPKIPYDLLKKYIAYARKNIHPVLSKEAMDEIKRYYVRMRKGFRKSGEDEGVQPIPITARQLEALIRLSE
AHARMRLSETVTREDARAAIQIIEEMIRKIATDEEGTLDVSILEVGKSSKKINKIDKLIDIIKSLESEGEFGAPEDKVVE
AAKQAGIGTENEVKKLINDLKRDARIYEPRAGFYRVL

Sequences:

>Translated_1157_residues
MDREDMIERYARFLREYVDDSGNEVYLNKLKDLLTVTPRRSLSIDWTHLNSFDPELAEELLKNPEDSILAAEDAIQIVLR
EPPLLREEEFKVHARFFNLPRTLLVKELGSEHINRLIQVDGIITRVSEVKPFVEKAVFVCKDCGNEMVRLQRPYDNIVKP
SKCDACGSRNVELDVEKSRFINFQSFRLQDRPESLKGGQMPRFIDAILLDDLVDTALPGDRVLVTGILRVILEQKDKRPI
FKKVLEVNHIEQLSKEIEELEITPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHKTVKKGIALALFGGVQRVLPDGTKLR
GESHVLLVGDPGVAKCVDYDTQVVLADGSLGKIGELVEGAIRRAKKEGTLGRVDDGFYAPIDLELYALDAKTLKVKKVKA
NIAWKRTAPERMFLIRTASGREIRVTPTHPFFVFENGQFKTRKAEELKASDFIAVPRIIPVAGKPTRLWDIEIEKPKTAK
SRLKLPEFADEEFWYVIGLLAGEGYAQNRNGSATIFFTNNDEKLIQKVYEYFRKLDLNPTIRKPHRGKSAKEVYVSSVEF
FRLFKHLGIAENSSKKKVPSQIFSARLEDIKAFLQGYFDAEGTVDRARPKITVVSASLELLRGVRHLLLRFGIKSQLHAT
RGIATNGKMKEAKTYYRLVITGKDVIKFRETIGFGVEEKAKLLAKVTNGIKLNTNVDVVPGVSKLLRELRESAGLRQKDL
GINRSTYLHYERGDRLPSREKLKIVVETLKEKSPDAPKKLKVLELLADSDIFWDRVVEVREYKPEHPWVYDLQVPEHHNF
IANDIFVHNSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAI
HEALEQQTISISKAGITATLNSRTTVIAAANPKYGRFNRHKSLPEQLDLPPTLLSRFDLIFLLLDEPDEKIDASIAEHIL
KVRRGEAEAVTPKIPYDLLKKYIAYARKNIHPVLSKEAMDEIKRYYVRMRKGFRKSGEDEGVQPIPITARQLEALIRLSE
AHARMRLSETVTREDARAAIQIIEEMIRKIATDEEGTLDVSILEVGKSSKKINKIDKLIDIIKSLESEGEFGAPEDKVVE
AAKQAGIGTENEVKKLINDLKRDARIYEPRAGFYRVL
>Mature_1157_residues
MDREDMIERYARFLREYVDDSGNEVYLNKLKDLLTVTPRRSLSIDWTHLNSFDPELAEELLKNPEDSILAAEDAIQIVLR
EPPLLREEEFKVHARFFNLPRTLLVKELGSEHINRLIQVDGIITRVSEVKPFVEKAVFVCKDCGNEMVRLQRPYDNIVKP
SKCDACGSRNVELDVEKSRFINFQSFRLQDRPESLKGGQMPRFIDAILLDDLVDTALPGDRVLVTGILRVILEQKDKRPI
FKKVLEVNHIEQLSKEIEELEITPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHKTVKKGIALALFGGVQRVLPDGTKLR
GESHVLLVGDPGVAKCVDYDTQVVLADGSLGKIGELVEGAIRRAKKEGTLGRVDDGFYAPIDLELYALDAKTLKVKKVKA
NIAWKRTAPERMFLIRTASGREIRVTPTHPFFVFENGQFKTRKAEELKASDFIAVPRIIPVAGKPTRLWDIEIEKPKTAK
SRLKLPEFADEEFWYVIGLLAGEGYAQNRNGSATIFFTNNDEKLIQKVYEYFRKLDLNPTIRKPHRGKSAKEVYVSSVEF
FRLFKHLGIAENSSKKKVPSQIFSARLEDIKAFLQGYFDAEGTVDRARPKITVVSASLELLRGVRHLLLRFGIKSQLHAT
RGIATNGKMKEAKTYYRLVITGKDVIKFRETIGFGVEEKAKLLAKVTNGIKLNTNVDVVPGVSKLLRELRESAGLRQKDL
GINRSTYLHYERGDRLPSREKLKIVVETLKEKSPDAPKKLKVLELLADSDIFWDRVVEVREYKPEHPWVYDLQVPEHHNF
IANDIFVHNSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAI
HEALEQQTISISKAGITATLNSRTTVIAAANPKYGRFNRHKSLPEQLDLPPTLLSRFDLIFLLLDEPDEKIDASIAEHIL
KVRRGEAEAVTPKIPYDLLKKYIAYARKNIHPVLSKEAMDEIKRYYVRMRKGFRKSGEDEGVQPIPITARQLEALIRLSE
AHARMRLSETVTREDARAAIQIIEEMIRKIATDEEGTLDVSILEVGKSSKKINKIDKLIDIIKSLESEGEFGAPEDKVVE
AAKQAGIGTENEVKKLINDLKRDARIYEPRAGFYRVL

Specific function: Has ATPase and DNA helicase activities. The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein) [H]

COG id: COG1241

COG function: function code L; Predicted ATPase involved in replication control, Cdc46/Mcm family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MCM domain [H]

Homologues:

Organism=Homo sapiens, GI33469919, Length=308, Percent_Identity=45.7792207792208, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI33469917, Length=308, Percent_Identity=45.7792207792208, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI23510448, Length=259, Percent_Identity=47.1042471042471, Blast_Score=234, Evalue=4e-61,
Organism=Homo sapiens, GI7427519, Length=272, Percent_Identity=45.5882352941176, Blast_Score=230, Evalue=7e-60,
Organism=Homo sapiens, GI33469968, Length=266, Percent_Identity=45.4887218045113, Blast_Score=225, Evalue=2e-58,
Organism=Homo sapiens, GI33469922, Length=266, Percent_Identity=45.4887218045113, Blast_Score=225, Evalue=2e-58,
Organism=Homo sapiens, GI19923727, Length=320, Percent_Identity=38.125, Blast_Score=216, Evalue=1e-55,
Organism=Homo sapiens, GI33469924, Length=320, Percent_Identity=38.125, Blast_Score=215, Evalue=2e-55,
Organism=Homo sapiens, GI6631095, Length=312, Percent_Identity=40.0641025641026, Blast_Score=214, Evalue=4e-55,
Organism=Homo sapiens, GI33356547, Length=394, Percent_Identity=35.5329949238579, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI310115110, Length=235, Percent_Identity=41.7021276595745, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI310128402, Length=235, Percent_Identity=41.7021276595745, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI310119838, Length=235, Percent_Identity=41.7021276595745, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI23397546, Length=271, Percent_Identity=32.8413284132841, Blast_Score=113, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508417, Length=319, Percent_Identity=45.4545454545455, Blast_Score=250, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71997752, Length=286, Percent_Identity=42.3076923076923, Blast_Score=224, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17562702, Length=268, Percent_Identity=44.7761194029851, Blast_Score=223, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17562700, Length=305, Percent_Identity=43.9344262295082, Blast_Score=222, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17554306, Length=284, Percent_Identity=42.6056338028169, Blast_Score=221, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71997563, Length=263, Percent_Identity=46.0076045627376, Blast_Score=220, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71997571, Length=263, Percent_Identity=46.0076045627376, Blast_Score=219, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6325276, Length=293, Percent_Identity=47.4402730375427, Blast_Score=266, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6321237, Length=278, Percent_Identity=47.1223021582734, Blast_Score=241, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6323304, Length=263, Percent_Identity=47.148288973384, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6319448, Length=299, Percent_Identity=40.133779264214, Blast_Score=210, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6319679, Length=305, Percent_Identity=40.655737704918, Blast_Score=208, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320803, Length=165, Percent_Identity=51.5151515151515, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17137242, Length=362, Percent_Identity=42.5414364640884, Blast_Score=247, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24645774, Length=264, Percent_Identity=48.4848484848485, Blast_Score=234, Evalue=3e-61,
Organism=Drosophila melanogaster, GI17530827, Length=270, Percent_Identity=45.9259259259259, Blast_Score=229, Evalue=7e-60,
Organism=Drosophila melanogaster, GI17137132, Length=279, Percent_Identity=42.6523297491039, Blast_Score=224, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24639835, Length=310, Percent_Identity=41.9354838709677, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI17647617, Length=266, Percent_Identity=42.8571428571429, Blast_Score=217, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24647251, Length=341, Percent_Identity=26.3929618768328, Blast_Score=111, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00493 MCM [H]

EC number: NA

Molecular weight: Translated: 131025; Mature: 131025

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50817 INTEIN_N_TER ; PS50818 INTEIN_C_TER ; PS50051 MCM_2 ; PS50943 HTH_CROC1 ; PS50819 INTEIN_ENDONUCLEASE ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREDMIERYARFLREYVDDSGNEVYLNKLKDLLTVTPRRSLSIDWTHLNSFDPELAEEL
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
LKNPEDSILAAEDAIQIVLREPPLLREEEFKVHARFFNLPRTLLVKELGSEHINRLIQVD
HCCCCCCEEEHHHHHHEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GIITRVSEVKPFVEKAVFVCKDCGNEMVRLQRPYDNIVKPSKCDACGSRNVELDVEKSRF
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHCCCCCCCCCCCCCCEEEEECHHHH
INFQSFRLQDRPESLKGGQMPRFIDAILLDDLVDTALPGDRVLVTGILRVILEQKDKRPI
CCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
FKKVLEVNHIEQLSKEIEELEITPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHKTVKKG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IALALFGGVQRVLPDGTKLRGESHVLLVGDPGVAKCVDYDTQVVLADGSLGKIGELVEGA
HHHHHHHHHHHHCCCCCEECCCCEEEEEECCCCHHHCCCCCEEEEECCCCCHHHHHHHHH
IRRAKKEGTLGRVDDGFYAPIDLELYALDAKTLKVKKVKANIAWKRTAPERMFLIRTASG
HHHHHHCCCCCCCCCCEECCEEEEEEEECCCEEEEEEEEECEEEECCCCCEEEEEEECCC
REIRVTPTHPFFVFENGQFKTRKAEELKASDFIAVPRIIPVAGKPTRLWDIEIEKPKTAK
CEEEEECCCCEEEEECCCCCCCHHHHHCCCCCEECCCEEECCCCCCEEEEEEECCCCCHH
SRLKLPEFADEEFWYVIGLLAGEGYAQNRNGSATIFFTNNDEKLIQKVYEYFRKLDLNPT
HHCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCC
IRKPHRGKSAKEVYVSSVEFFRLFKHLGIAENSSKKKVPSQIFSARLEDIKAFLQGYFDA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EGTVDRARPKITVVSASLELLRGVRHLLLRFGIKSQLHATRGIATNGKMKEAKTYYRLVI
CCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHCCEEEEEEE
TGKDVIKFRETIGFGVEEKAKLLAKVTNGIKLNTNVDVVPGVSKLLRELRESAGLRQKDL
ECHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCCHHHC
GINRSTYLHYERGDRLPSREKLKIVVETLKEKSPDAPKKLKVLELLADSDIFWDRVVEVR
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
EYKPEHPWVYDLQVPEHHNFIANDIFVHNSQILRYVANLAPRAIYTSGKSSSAAGLTAAA
HCCCCCCEEEEEECCCCCCCHHHHEEEEHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHH
VRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAIHEALEQQTISISKAGITATL
HHHCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCEEEEE
NSRTTVIAAANPKYGRFNRHKSLPEQLDLPPTLLSRFDLIFLLLDEPDEKIDASIAEHIL
CCCEEEEEECCCCCCCCCHHCCCHHHCCCCHHHHHHHCEEEEEECCCCHHHHHHHHHHHH
KVRRGEAEAVTPKIPYDLLKKYIAYARKNIHPVLSKEAMDEIKRYYVRMRKGFRKSGEDE
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVQPIPITARQLEALIRLSEAHARMRLSETVTREDARAAIQIIEEMIRKIATDEEGTLDV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
SILEVGKSSKKINKIDKLIDIIKSLESEGEFGAPEDKVVEAAKQAGIGTENEVKKLINDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
KRDARIYEPRAGFYRVL
HHHCEEECCCCCCEECC
>Mature Secondary Structure
MDREDMIERYARFLREYVDDSGNEVYLNKLKDLLTVTPRRSLSIDWTHLNSFDPELAEEL
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
LKNPEDSILAAEDAIQIVLREPPLLREEEFKVHARFFNLPRTLLVKELGSEHINRLIQVD
HCCCCCCEEEHHHHHHEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GIITRVSEVKPFVEKAVFVCKDCGNEMVRLQRPYDNIVKPSKCDACGSRNVELDVEKSRF
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHCCCCCCCCCCCCCCEEEEECHHHH
INFQSFRLQDRPESLKGGQMPRFIDAILLDDLVDTALPGDRVLVTGILRVILEQKDKRPI
CCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
FKKVLEVNHIEQLSKEIEELEITPEDEQKIRELAKRKDIVDAIVDSIAPAIWGHKTVKKG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IALALFGGVQRVLPDGTKLRGESHVLLVGDPGVAKCVDYDTQVVLADGSLGKIGELVEGA
HHHHHHHHHHHHCCCCCEECCCCEEEEEECCCCHHHCCCCCEEEEECCCCCHHHHHHHHH
IRRAKKEGTLGRVDDGFYAPIDLELYALDAKTLKVKKVKANIAWKRTAPERMFLIRTASG
HHHHHHCCCCCCCCCCEECCEEEEEEEECCCEEEEEEEEECEEEECCCCCEEEEEEECCC
REIRVTPTHPFFVFENGQFKTRKAEELKASDFIAVPRIIPVAGKPTRLWDIEIEKPKTAK
CEEEEECCCCEEEEECCCCCCCHHHHHCCCCCEECCCEEECCCCCCEEEEEEECCCCCHH
SRLKLPEFADEEFWYVIGLLAGEGYAQNRNGSATIFFTNNDEKLIQKVYEYFRKLDLNPT
HHCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCC
IRKPHRGKSAKEVYVSSVEFFRLFKHLGIAENSSKKKVPSQIFSARLEDIKAFLQGYFDA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EGTVDRARPKITVVSASLELLRGVRHLLLRFGIKSQLHATRGIATNGKMKEAKTYYRLVI
CCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHCCEEEEEEE
TGKDVIKFRETIGFGVEEKAKLLAKVTNGIKLNTNVDVVPGVSKLLRELRESAGLRQKDL
ECHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCCHHHC
GINRSTYLHYERGDRLPSREKLKIVVETLKEKSPDAPKKLKVLELLADSDIFWDRVVEVR
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
EYKPEHPWVYDLQVPEHHNFIANDIFVHNSQILRYVANLAPRAIYTSGKSSSAAGLTAAA
HCCCCCCEEEEEECCCCCCCHHHHEEEEHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHH
VRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAIHEALEQQTISISKAGITATL
HHHCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCEEEEE
NSRTTVIAAANPKYGRFNRHKSLPEQLDLPPTLLSRFDLIFLLLDEPDEKIDASIAEHIL
CCCEEEEEECCCCCCCCCHHCCCHHHCCCCHHHHHHHCEEEEEECCCCHHHHHHHHHHHH
KVRRGEAEAVTPKIPYDLLKKYIAYARKNIHPVLSKEAMDEIKRYYVRMRKGFRKSGEDE
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVQPIPITARQLEALIRLSEAHARMRLSETVTREDARAAIQIIEEMIRKIATDEEGTLDV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
SILEVGKSSKKINKIDKLIDIIKSLESEGEFGAPEDKVVEAAKQAGIGTENEVKKLINDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
KRDARIYEPRAGFYRVL
HHHCEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]