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The map label for this gene is fabR [H]

Identifier: 209696288

GI number: 209696288

Start: 3134265

End: 3134963

Strand: Reverse

Name: fabR [H]

Synonym: VSAL_I2889

Alternate gene names: 209696288

Gene position: 3134963-3134265 (Counterclockwise)

Preceding gene: 209696290

Following gene: 209696287

Centisome position: 94.28

GC content: 41.06

Gene sequence:

>699_bases
ATGCAATATATGGTAAATAATATGTATCCTGAATTTGAAGCTGATGATCTTAATGCAGTGTTAGAAGTAAAGCAGCCAGT
AAGCACTAAAGGTGTAAGGGCTCAGCAAAAAGAAAGAACACGCAGAACCATTATAGATGCCGCGTTTTGCCTACTATGTG
CCGAACGAGGTTTCATGAGCTTGAGTTTACGAGAAGTAACAAGAGAAGCTGGTATCGCGCCTACGTCGTTTTATCGTCAT
TTTAAAGATATGGATGAGCTAGGGCTGACTTTAGTTGATGAAGGTGGACTTATTTTACGTCAGTTAATGCGTCAAGCTCG
TCAGCGTATTGTGGTAGAAGGGAGTGTTATCCGAACATCGGTTGAAACCTTCATGGAATTTATTGAAGGTAGTCCAAACG
TATTTCGATTGTTATTACGTGAACGTTCAGGAACTTCATCTGCTTTTAGAGCAGCAGTGGCTCGTGAGATCCAACATTTT
GTTGCGGAACTTACTGAATATTTGATTGCCACGACAGGTGTTGCTAGAGAAGAAGCGTCAGTTCAAGCTGAGGCGTCAGT
TACCTTAGTATTCAGTTCTGGTGCGGAGGCGCTCGACCTAGATACGCCTCATAGAGATGAATTGTCAAAACGGTTAATTT
TCCAATTACGTATGCTATCAAAAGGTGCTTATTGGTATCGAAAAGAAAATAAGATTTAG

Upstream 100 bases:

>100_bases
GCGGTAAATCATGTGATAATAGATTTCAGTATTTACAGTGGTAGCCAAAAATCGATAATGTGGACTAGCGAATAGTTTGT
GATACCCACTCAATTAACTT

Downstream 100 bases:

>100_bases
ATGCATTGTTCACCGTGAATCAATGCCTACACGAGGTAAACAACATGACACATGAAAATAGTAGAAATGAACGTAAAACA
TTAGCGCTATCTGTGGTGAC

Product: DNA-binding transcriptional repressor FabR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MQYMVNNMYPEFEADDLNAVLEVKQPVSTKGVRAQQKERTRRTIIDAAFCLLCAERGFMSLSLREVTREAGIAPTSFYRH
FKDMDELGLTLVDEGGLILRQLMRQARQRIVVEGSVIRTSVETFMEFIEGSPNVFRLLLRERSGTSSAFRAAVAREIQHF
VAELTEYLIATTGVAREEASVQAEASVTLVFSSGAEALDLDTPHRDELSKRLIFQLRMLSKGAYWYRKENKI

Sequences:

>Translated_232_residues
MQYMVNNMYPEFEADDLNAVLEVKQPVSTKGVRAQQKERTRRTIIDAAFCLLCAERGFMSLSLREVTREAGIAPTSFYRH
FKDMDELGLTLVDEGGLILRQLMRQARQRIVVEGSVIRTSVETFMEFIEGSPNVFRLLLRERSGTSSAFRAAVAREIQHF
VAELTEYLIATTGVAREEASVQAEASVTLVFSSGAEALDLDTPHRDELSKRLIFQLRMLSKGAYWYRKENKI
>Mature_232_residues
MQYMVNNMYPEFEADDLNAVLEVKQPVSTKGVRAQQKERTRRTIIDAAFCLLCAERGFMSLSLREVTREAGIAPTSFYRH
FKDMDELGLTLVDEGGLILRQLMRQARQRIVVEGSVIRTSVETFMEFIEGSPNVFRLLLRERSGTSSAFRAAVAREIQHF
VAELTEYLIATTGVAREEASVQAEASVTLVFSSGAEALDLDTPHRDELSKRLIFQLRMLSKGAYWYRKENKI

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=202, Percent_Identity=70.7920792079208, Blast_Score=287, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 26380; Mature: 26380

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYMVNNMYPEFEADDLNAVLEVKQPVSTKGVRAQQKERTRRTIIDAAFCLLCAERGFMS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LSLREVTREAGIAPTSFYRHFKDMDELGLTLVDEGGLILRQLMRQARQRIVVEGSVIRTS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
VETFMEFIEGSPNVFRLLLRERSGTSSAFRAAVAREIQHFVAELTEYLIATTGVAREEAS
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
VQAEASVTLVFSSGAEALDLDTPHRDELSKRLIFQLRMLSKGAYWYRKENKI
CEECCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure
MQYMVNNMYPEFEADDLNAVLEVKQPVSTKGVRAQQKERTRRTIIDAAFCLLCAERGFMS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LSLREVTREAGIAPTSFYRHFKDMDELGLTLVDEGGLILRQLMRQARQRIVVEGSVIRTS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
VETFMEFIEGSPNVFRLLLRERSGTSSAFRAAVAREIQHFVAELTEYLIATTGVAREEAS
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
VQAEASVTLVFSSGAEALDLDTPHRDELSKRLIFQLRMLSKGAYWYRKENKI
CEECCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA