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The map label for this gene is murB [H]

Identifier: 209696276

GI number: 209696276

Start: 3117192

End: 3118232

Strand: Reverse

Name: murB [H]

Synonym: VSAL_I2877

Alternate gene names: 209696276

Gene position: 3118232-3117192 (Counterclockwise)

Preceding gene: 209696283

Following gene: 209696275

Centisome position: 93.78

GC content: 33.43

Gene sequence:

>1041_bases
ATGAATATTTTATTAAATAAAAATCTTCGCCCTTTTAATAGTTTTTCTATTGACGTTAATGCGGATGTTATTATCGAAGC
AAATTCAATAAATGATTTTATTGATATATGGTCAAATGACGATTATCGCTCATCGATTAAGTTACCATTAGGGCGAGGCA
GTAACACTTTATTTTGTAATGATTTTTCTGGTGTTATTGTACTTAACCGAATTTTGGGTAAAGAAGTAACGGAAACAGAA
ACTGATTATTTATTATCTGTTTCAAGCGGCGAAGATTGGCCTAGTTTTGTTAAGTGGTGTGTAGAGCATAATTACAATGG
TATTGAAAATCTTGCAATGATCCCTGGTTGTGTAGGATCTGCTCCTATTCAAAATATTGGTGCATACGGTTTAGAGTTTA
AAGATGTTTGTGATTATGTTGAGTATTTAGATTTAGAATCATTGAACATTAAACGTTTATCAAAAAGTGAATGTGATTTT
GGTTATAGAGATTCAATTTTCAAGAAATCATTAAAAGATAAAGTAATCATTACATCTGTCGGTTTTAAATTATCAAAATC
GTGGGCCCCACTTTTGACGTATGGGCCGCTTGCTGATTTAAGTAGTGTGGTAGGAGTAACCGCTGAATCTGTATTTAAAG
CTATTTGTGATATTCGCTCTCTTAAATTACCCAATCCTGAAGTGCTTGGGAATGCCGGTAGTTTTTTTAAAAATCCTATC
GTATCAGATGAATGTTATTTAAAACTATCGAAAAATTTTCCTACTCTGCCTGCATATACCGTCTCTGATGGAAAGAAAAT
ATCTGCAGGTTGGTTGATAGATCACGCGGGACTTAAAGGTTTCTCGATTAACGATGCCCAAGTGCATAAAGAACAAGCTC
TTGTACTAATCAACAATGGAAATGCAACATCGAAAGATATTTTAGAGTTAGCTCGCCATGTTCAAAAAACAATTTTTGAT
ATTTATCATATAGAGTTGGAACATGAAGTTCGATTTTATTTTTCGGGCAAAGAAACGTCACTCTCGGAGTTGTTTGAATG
A

Upstream 100 bases:

>100_bases
TTGTTTAAGTGAGAAACAGTAAGATTCATTCGTTGGATTCTATGTAGATTGTATTCATTGCGTTAGAATGTACTTAATCT
AACCTATGAAATAAAGTGAT

Downstream 100 bases:

>100_bases
AGGAACACTTGAAAAAGCTAGAAATATTGAAGGCGCTCAGTGATGGTTCTTTTCATTCAGGTGAGGACTTAGGTGATGAC
ATTGGCGTATCCAGAGCTGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNILLNKNLRPFNSFSIDVNADVIIEANSINDFIDIWSNDDYRSSIKLPLGRGSNTLFCNDFSGVIVLNRILGKEVTETE
TDYLLSVSSGEDWPSFVKWCVEHNYNGIENLAMIPGCVGSAPIQNIGAYGLEFKDVCDYVEYLDLESLNIKRLSKSECDF
GYRDSIFKKSLKDKVIITSVGFKLSKSWAPLLTYGPLADLSSVVGVTAESVFKAICDIRSLKLPNPEVLGNAGSFFKNPI
VSDECYLKLSKNFPTLPAYTVSDGKKISAGWLIDHAGLKGFSINDAQVHKEQALVLINNGNATSKDILELARHVQKTIFD
IYHIELEHEVRFYFSGKETSLSELFE

Sequences:

>Translated_346_residues
MNILLNKNLRPFNSFSIDVNADVIIEANSINDFIDIWSNDDYRSSIKLPLGRGSNTLFCNDFSGVIVLNRILGKEVTETE
TDYLLSVSSGEDWPSFVKWCVEHNYNGIENLAMIPGCVGSAPIQNIGAYGLEFKDVCDYVEYLDLESLNIKRLSKSECDF
GYRDSIFKKSLKDKVIITSVGFKLSKSWAPLLTYGPLADLSSVVGVTAESVFKAICDIRSLKLPNPEVLGNAGSFFKNPI
VSDECYLKLSKNFPTLPAYTVSDGKKISAGWLIDHAGLKGFSINDAQVHKEQALVLINNGNATSKDILELARHVQKTIFD
IYHIELEHEVRFYFSGKETSLSELFE
>Mature_346_residues
MNILLNKNLRPFNSFSIDVNADVIIEANSINDFIDIWSNDDYRSSIKLPLGRGSNTLFCNDFSGVIVLNRILGKEVTETE
TDYLLSVSSGEDWPSFVKWCVEHNYNGIENLAMIPGCVGSAPIQNIGAYGLEFKDVCDYVEYLDLESLNIKRLSKSECDF
GYRDSIFKKSLKDKVIITSVGFKLSKSWAPLLTYGPLADLSSVVGVTAESVFKAICDIRSLKLPNPEVLGNAGSFFKNPI
VSDECYLKLSKNFPTLPAYTVSDGKKISAGWLIDHAGLKGFSINDAQVHKEQALVLINNGNATSKDILELARHVQKTIFD
IYHIELEHEVRFYFSGKETSLSELFE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=340, Percent_Identity=46.7647058823529, Blast_Score=327, Evalue=9e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38597; Mature: 38597

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLNKNLRPFNSFSIDVNADVIIEANSINDFIDIWSNDDYRSSIKLPLGRGSNTLFCN
CEEEECCCCCCCCCEEEECCCEEEEEECCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEE
DFSGVIVLNRILGKEVTETETDYLLSVSSGEDWPSFVKWCVEHNYNGIENLAMIPGCVGS
CCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCC
APIQNIGAYGLEFKDVCDYVEYLDLESLNIKRLSKSECDFGYRDSIFKKSLKDKVIITSV
CCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEC
GFKLSKSWAPLLTYGPLADLSSVVGVTAESVFKAICDIRSLKLPNPEVLGNAGSFFKNPI
CCEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHCCCC
VSDECYLKLSKNFPTLPAYTVSDGKKISAGWLIDHAGLKGFSINDAQVHKEQALVLINNG
CCCCEEEEECCCCCCCCEEECCCCCEEECCEEEECCCCCCCCCCHHHCCCCCEEEEEECC
NATSKDILELARHVQKTIFDIYHIELEHEVRFYFSGKETSLSELFE
CCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCHHHHCC
>Mature Secondary Structure
MNILLNKNLRPFNSFSIDVNADVIIEANSINDFIDIWSNDDYRSSIKLPLGRGSNTLFCN
CEEEECCCCCCCCCEEEECCCEEEEEECCCCCHHHHCCCCCCCCEEEEEECCCCCEEEEE
DFSGVIVLNRILGKEVTETETDYLLSVSSGEDWPSFVKWCVEHNYNGIENLAMIPGCVGS
CCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCC
APIQNIGAYGLEFKDVCDYVEYLDLESLNIKRLSKSECDFGYRDSIFKKSLKDKVIITSV
CCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEC
GFKLSKSWAPLLTYGPLADLSSVVGVTAESVFKAICDIRSLKLPNPEVLGNAGSFFKNPI
CCEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHCCCC
VSDECYLKLSKNFPTLPAYTVSDGKKISAGWLIDHAGLKGFSINDAQVHKEQALVLINNG
CCCCEEEEECCCCCCCCEEECCCCCEEECCEEEECCCCCCCCCCHHHCCCCCEEEEEECC
NATSKDILELARHVQKTIFDIYHIELEHEVRFYFSGKETSLSELFE
CCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA