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The map label for this gene is gpsA [H]

Identifier: 209696207

GI number: 209696207

Start: 3032793

End: 3033824

Strand: Reverse

Name: gpsA [H]

Synonym: VSAL_I2801

Alternate gene names: 209696207

Gene position: 3033824-3032793 (Counterclockwise)

Preceding gene: 209696208

Following gene: 209696206

Centisome position: 91.24

GC content: 43.51

Gene sequence:

>1032_bases
ATGGTCACAATGACAACACAAAACGATTACTCTGATATTTATATGACCGTACTTGGTGCCGGTTCTTATGGTACATCGCT
GGCAATTTCGTTAGCTCGTAATGGCGCAAAAGTCATTTTATGGGGACACGAGAAAGCGCATATGGATCGTTTAGACGCTG
ATCGTGCGAATGAAGAATTTCTGCCTGGTGTTGTTTTTCCACCGTCATTATTCATGGAAACTGATTTAGAAAAAGCCGTT
CAAGCAAGTCGTGATTTATTGGTGGTTGTGCCAAGTCATGTGTTTGGATTAGTGCTAGGTAATGTGAAACCGTTTCTACG
TGAAGATTCTCGCGTATGTTGGGCGACAAAAGGGCTTGAGCCTGAAACAGGTCGTTTATTAAAAGAAGTGGCAGTAGAAG
CATTGGGTGAATCACACTCTCTGGCTGTCTTATCTGGACCTACTTTTGCTAAAGAACTTGCTTCTGGTATGCCAACCGCG
ATTGCTGTGGCGTCTCCTGATAAGCAATTTGTGAAAGATCTTCAAGAGAAAATTCACTGTTCAAAAACGTTCCGTGTGTA
TGCGAATAATGACTTCACTGGAATGCAACTTGGCGGTGCTGTGAAAAATGTGATCGCGATTGGGGCGGGTATGTCTGATG
GCATTGGTTTTGGTGCAAATGCACGTACGGCATTAATTACTCGTGGTTTGGCAGAAATGACCCGTTTAGGTGTGGCATTA
GGCGCTGAAGCGGAAACCTTTATGGGGATGGCCGGTTTGGGCGATTTAGTGCTTACTTGTACTGATAACCAATCACGCAA
CCGTCGTTTTGGTCTTGCTTTAGGTCAAGGTGGGGACGTAGAAAGTGCTCAGGTTGAAATCGGACAAGTTGTAGAAGGGT
ATAGAAACACGAAAGAAGTGTTTTTACTTGCAGAACGAATGGGTGTTGAAATGCCTATAGTTGAGCAAATTTATCAAGTA
TTGTATCAAGGGAAAGATGCAAGAGTTGCTGCGCAGGATTTATTAGCACGCGACAAAAAATCAGAATCGTAA

Upstream 100 bases:

>100_bases
TTTATCTAATATGGTTTCTATATCTACTATAGCTCCTATATTTTGATAACAAGTGCATTTTGTTTTTATTACCCTAGTAT
CTTTTGATACCAGTTTTTGG

Downstream 100 bases:

>100_bases
TTCAAGGATGGTATGAAGATGAATGAATGTAAGAAACACAAAGTATGGGAAAAAATTGTTCAGGAAGCGCGCGAGCAATC
TGAGCAAGAACCCATACTTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVTMTTQNDYSDIYMTVLGAGSYGTSLAISLARNGAKVILWGHEKAHMDRLDADRANEEFLPGVVFPPSLFMETDLEKAV
QASRDLLVVVPSHVFGLVLGNVKPFLREDSRVCWATKGLEPETGRLLKEVAVEALGESHSLAVLSGPTFAKELASGMPTA
IAVASPDKQFVKDLQEKIHCSKTFRVYANNDFTGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGVAL
GAEAETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGGDVESAQVEIGQVVEGYRNTKEVFLLAERMGVEMPIVEQIYQV
LYQGKDARVAAQDLLARDKKSES

Sequences:

>Translated_343_residues
MVTMTTQNDYSDIYMTVLGAGSYGTSLAISLARNGAKVILWGHEKAHMDRLDADRANEEFLPGVVFPPSLFMETDLEKAV
QASRDLLVVVPSHVFGLVLGNVKPFLREDSRVCWATKGLEPETGRLLKEVAVEALGESHSLAVLSGPTFAKELASGMPTA
IAVASPDKQFVKDLQEKIHCSKTFRVYANNDFTGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGVAL
GAEAETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGGDVESAQVEIGQVVEGYRNTKEVFLLAERMGVEMPIVEQIYQV
LYQGKDARVAAQDLLARDKKSES
>Mature_343_residues
MVTMTTQNDYSDIYMTVLGAGSYGTSLAISLARNGAKVILWGHEKAHMDRLDADRANEEFLPGVVFPPSLFMETDLEKAV
QASRDLLVVVPSHVFGLVLGNVKPFLREDSRVCWATKGLEPETGRLLKEVAVEALGESHSLAVLSGPTFAKELASGMPTA
IAVASPDKQFVKDLQEKIHCSKTFRVYANNDFTGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGVAL
GAEAETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGGDVESAQVEIGQVVEGYRNTKEVFLLAERMGVEMPIVEQIYQV
LYQGKDARVAAQDLLARDKKSES

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=336, Percent_Identity=27.9761904761905, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24307999, Length=338, Percent_Identity=25.7396449704142, Blast_Score=111, Evalue=7e-25,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=71.6463414634146, Blast_Score=482, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI32564399, Length=342, Percent_Identity=26.0233918128655, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32564403, Length=351, Percent_Identity=25.6410256410256, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=339, Percent_Identity=25.6637168141593, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=336, Percent_Identity=23.2142857142857, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210134, Length=188, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.4457478005865, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=27.0893371757925, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17136202, Length=335, Percent_Identity=27.4626865671642, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136204, Length=335, Percent_Identity=27.4626865671642, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136200, Length=335, Percent_Identity=27.4626865671642, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI22026922, Length=334, Percent_Identity=25.4491017964072, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45551945, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648969, Length=186, Percent_Identity=31.1827956989247, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36878; Mature: 36878

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTMTTQNDYSDIYMTVLGAGSYGTSLAISLARNGAKVILWGHEKAHMDRLDADRANEEF
CEEECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHCCCCCCCCCC
LPGVVFPPSLFMETDLEKAVQASRDLLVVVPSHVFGLVLGNVKPFLREDSRVCWATKGLE
CCCEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHCCCCEEEEECCCC
PETGRLLKEVAVEALGESHSLAVLSGPTFAKELASGMPTAIAVASPDKQFVKDLQEKIHC
CHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SKTFRVYANNDFTGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGVAL
CCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GAEAETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGGDVESAQVEIGQVVEGYRNTKEV
CCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHH
FLLAERMGVEMPIVEQIYQVLYQGKDARVAAQDLLARDKKSES
EEEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVTMTTQNDYSDIYMTVLGAGSYGTSLAISLARNGAKVILWGHEKAHMDRLDADRANEEF
CEEECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHCCCCCCCCCC
LPGVVFPPSLFMETDLEKAVQASRDLLVVVPSHVFGLVLGNVKPFLREDSRVCWATKGLE
CCCEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHCCCCEEEEECCCC
PETGRLLKEVAVEALGESHSLAVLSGPTFAKELASGMPTAIAVASPDKQFVKDLQEKIHC
CHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SKTFRVYANNDFTGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMTRLGVAL
CCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GAEAETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGGDVESAQVEIGQVVEGYRNTKEV
CCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHH
FLLAERMGVEMPIVEQIYQVLYQGKDARVAAQDLLARDKKSES
EEEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA