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The map label for this gene is trpS [H]

Identifier: 209696134

GI number: 209696134

Start: 2954038

End: 2955054

Strand: Direct

Name: trpS [H]

Synonym: VSAL_I2728

Alternate gene names: 209696134

Gene position: 2954038-2955054 (Clockwise)

Preceding gene: 209696133

Following gene: 209696135

Centisome position: 88.84

GC content: 43.36

Gene sequence:

>1017_bases
ATGAGCAAGCCCATCGTATTAAGTGGTGTTCAACCGTCAGGTGAACTGAGTATTGGTAACTACTTGGGTGCTCTACGTCA
ATGGCAACAGATGCAAGACGATTATGATTGTCAGTACTGTGTTGTAGACCTTCATGCCATTACGGTTCGTCAAGATCCTA
AAGCATTGCATGAAGCGACACTCGATGCTCTGGCAATTTGTCTCGCGGTTGGTGTTGATCCAAAGAAGAGCACGTTATTT
GTTCAGTCACATGTACCAGAGCATGCTCAGCTAGGTTGGCTTCTTAACTGTTATACCCAAATGGGTGAACTAAGTCGTAT
GACTCAGTTTAAAGATAAGTCTGCTCGTCATTCAAATGATGTGAATGTTGGGTTATTCGGTTACCCAGTCTTAATGGCGG
CTGATATTTTATTGTACGGCGCGCATCAAGTGCCTGTGGGCAGTGATCAAAAGCAGCATTTAGAATTAGCGCGTGATATT
GCGAATCGTTTCAATAATGCTTACTGCCCTGAATCGCCTTTATTCACGGTTCCAGAACCCTACATCCCACAAGTGAATGC
GCGTGTGATGAGTCTACAAGATGCGACGAAGAAAATGTCTAAATCAGATGATAACCGTAAGAATGTTATTACGCTGTTAG
AAGATCCTAAGTCAATTCTTAAGAAAATCAATAAAGCGCAAACAGACGCAGAAATGCCCCCTCGTATTGCTCATGATTGG
GAAAACAAAGCCGGTATTTCAAACCTGATGGGTCTGTATTCTGCAGCAAGTGGCCAAACGTTTGAAGAGATCGAAGCTCA
ATACCAAGGTGTTGAAATGTATGGTCCATTCAAGAAAGACGTTGGTGAAGCGATTGTGACGATGCTAGAGCCGATTCAAT
CTGAATATAAACGTATTCGTGATGATCGTACGTATATGGATTCAGTAATGAAAGCGGGAGCTGAAAAGGCATCAGAACGC
GCTGCAGTGACACTGAAAAAAGCGTATGAAGCCGTTGGTTTTGTTACTCGCCCATAG

Upstream 100 bases:

>100_bases
GGATTAACGTAATTCGGCATTATTAATATCGATAGAATAACCATTAAATGATCCGATAACGGGTCATTTAATTTTTACAG
TTAAACAAGGAATCATAACC

Downstream 100 bases:

>100_bases
TTAGTCTGCCAATGAGTTAAATGAATTGCTCGTTAGCTTTTTGCTAGCGAGCAATTTTTATTTCTTCTTCTCTACTTAGC
GAATGTAGTCTTTTTTATGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLF
VQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDI
ANRFNNAYCPESPLFTVPEPYIPQVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSILKKINKAQTDAEMPPRIAHDW
ENKAGISNLMGLYSAASGQTFEEIEAQYQGVEMYGPFKKDVGEAIVTMLEPIQSEYKRIRDDRTYMDSVMKAGAEKASER
AAVTLKKAYEAVGFVTRP

Sequences:

>Translated_338_residues
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLF
VQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDI
ANRFNNAYCPESPLFTVPEPYIPQVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSILKKINKAQTDAEMPPRIAHDW
ENKAGISNLMGLYSAASGQTFEEIEAQYQGVEMYGPFKKDVGEAIVTMLEPIQSEYKRIRDDRTYMDSVMKAGAEKASER
AAVTLKKAYEAVGFVTRP
>Mature_337_residues
SKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPKKSTLFV
QSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSNDVNVGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDIA
NRFNNAYCPESPLFTVPEPYIPQVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSILKKINKAQTDAEMPPRIAHDWE
NKAGISNLMGLYSAASGQTFEEIEAQYQGVEMYGPFKKDVGEAIVTMLEPIQSEYKRIRDDRTYMDSVMKAGAEKASERA
AVTLKKAYEAVGFVTRP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=335, Percent_Identity=40, Blast_Score=265, Evalue=6e-71,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=50.8379888268156, Blast_Score=187, Evalue=8e-48,
Organism=Escherichia coli, GI1789786, Length=338, Percent_Identity=64.2011834319527, Blast_Score=458, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=34.3195266272189, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=34.3195266272189, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=39.8860398860399, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=41.4414414414414, Blast_Score=244, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37701; Mature: 37570

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEAT
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
LDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSND
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNVGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDIANRFNNAYCPESPLFTVPEP
CEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YIPQVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSILKKINKAQTDAEMPPRIAHDW
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHCC
ENKAGISNLMGLYSAASGQTFEEIEAQYQGVEMYGPFKKDVGEAIVTMLEPIQSEYKRIR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDRTYMDSVMKAGAEKASERAAVTLKKAYEAVGFVTRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDPKALHEAT
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
LDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHSND
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNVGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDIANRFNNAYCPESPLFTVPEP
CEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YIPQVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSILKKINKAQTDAEMPPRIAHDW
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHCC
ENKAGISNLMGLYSAASGQTFEEIEAQYQGVEMYGPFKKDVGEAIVTMLEPIQSEYKRIR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDRTYMDSVMKAGAEKASERAAVTLKKAYEAVGFVTRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA