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The map label for this gene is kcsA [H]

Identifier: 209696087

GI number: 209696087

Start: 2901363

End: 2902124

Strand: Direct

Name: kcsA [H]

Synonym: VSAL_I2679

Alternate gene names: 209696087

Gene position: 2901363-2902124 (Clockwise)

Preceding gene: 209696083

Following gene: 209696089

Centisome position: 87.25

GC content: 37.4

Gene sequence:

>762_bases
ATGAATCATACCAAAATTGACCTTAAACCCATGAGCTTAATGTCACTGATACTGTCGTTTTTATCATTAATTGTGATCTC
AAGCTTGCTGTTTCTACCACTAAATAGTGCCAGTAAAGCAATGTTGATTGGTATCGACACCACCATCTGTGCCTTGTTTC
TTCTGCAATTAAGTATTGATTTACTTAGAAGTCAAGATCGTCGTCAATATATGAAAGATCATTGGATCGATTTTATTGCC
AGTATTCCGATCATTGAACCCATTCGATATGCCCGAATTTTTCATATTTTAAGAATATGCCGACTTTTCCGATCCAGTCA
ATCCGTCTTAAAACAGATTAAGAAAAACCGAAAAGAAGCCACTATTGCTTCTATTCTTGTGTTGATGGTGACATTAATTT
CGCTTGGCTCTGTCTTTATGCTTGTATTTGAAGGGCAAAACCCGAATGCAAACATACAAACCGCAGGAGATGCGATATGG
TGGGCTTTTGTGACAATATCAACCGTCGGTTATGGTGATCATTATCCTATTACTGTTGCGGGAAAAATACTGGCCGTTTT
TATCATCATTTCAGGCGTTGGGATCTTTGGTATGATTTCAGGTTTAATTACCTCCATAATTACAGAGCCTGAAAAAGTCA
GAGAAAAGCATATGCACGAGCAAGAGCAAATAGTACGAAGCCAAAAGCTTGATTTGCTCCTCCAGCAACAAACCGAAATT
TTAGAACGACTTAATCAAATCGAAAATAACAAAGAGAAGTAA

Upstream 100 bases:

>100_bases
TCATTCCTTTAAGTCTCTGATTATTTAGTGCATCATGGAGCAAGCTGTGCAAGCCTATGTGCACATTTTTTATATCTACT
GAGATACATATAAATTTAAC

Downstream 100 bases:

>100_bases
GCACACTTCTCTTTATATTTCATGACAGCTTAAGACAATAAATAGATCGTATTTTTATTGCCAATAAGGAGGGTACGCTA
ACCCAGCCCGTCGTGTTTGT

Product: ion transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNHTKIDLKPMSLMSLILSFLSLIVISSLLFLPLNSASKAMLIGIDTTICALFLLQLSIDLLRSQDRRQYMKDHWIDFIA
SIPIIEPIRYARIFHILRICRLFRSSQSVLKQIKKNRKEATIASILVLMVTLISLGSVFMLVFEGQNPNANIQTAGDAIW
WAFVTISTVGYGDHYPITVAGKILAVFIIISGVGIFGMISGLITSIITEPEKVREKHMHEQEQIVRSQKLDLLLQQQTEI
LERLNQIENNKEK

Sequences:

>Translated_253_residues
MNHTKIDLKPMSLMSLILSFLSLIVISSLLFLPLNSASKAMLIGIDTTICALFLLQLSIDLLRSQDRRQYMKDHWIDFIA
SIPIIEPIRYARIFHILRICRLFRSSQSVLKQIKKNRKEATIASILVLMVTLISLGSVFMLVFEGQNPNANIQTAGDAIW
WAFVTISTVGYGDHYPITVAGKILAVFIIISGVGIFGMISGLITSIITEPEKVREKHMHEQEQIVRSQKLDLLLQQQTEI
LERLNQIENNKEK
>Mature_253_residues
MNHTKIDLKPMSLMSLILSFLSLIVISSLLFLPLNSASKAMLIGIDTTICALFLLQLSIDLLRSQDRRQYMKDHWIDFIA
SIPIIEPIRYARIFHILRICRLFRSSQSVLKQIKKNRKEATIASILVLMVTLISLGSVFMLVFEGQNPNANIQTAGDAIW
WAFVTISTVGYGDHYPITVAGKILAVFIIISGVGIFGMISGLITSIITEPEKVREKHMHEQEQIVRSQKLDLLLQQQTEI
LERLNQIENNKEK

Specific function: Acts as a potassium ion channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI88758565, Length=113, Percent_Identity=33.6283185840708, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4504817, Length=113, Percent_Identity=35.3982300884956, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI119395748, Length=113, Percent_Identity=32.7433628318584, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI26051262, Length=138, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051260, Length=138, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051266, Length=138, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051264, Length=138, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4504821, Length=113, Percent_Identity=34.5132743362832, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI25952087, Length=113, Percent_Identity=35.3982300884956, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI25952108, Length=177, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI26051268, Length=140, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27436974, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031819, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147242, Length=135, Percent_Identity=32.5925925925926, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147238, Length=135, Percent_Identity=32.5925925925926, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994134, Length=125, Percent_Identity=30.4, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206869, Length=134, Percent_Identity=29.1044776119403, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25148255, Length=134, Percent_Identity=29.1044776119403, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24642916, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24642914, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45555859, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45549143, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221330119, Length=152, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24642910, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281363095, Length=152, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221330117, Length=152, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363097, Length=152, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 28704; Mature: 28704

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHTKIDLKPMSLMSLILSFLSLIVISSLLFLPLNSASKAMLIGIDTTICALFLLQLSID
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHH
LLRSQDRRQYMKDHWIDFIASIPIIEPIRYARIFHILRICRLFRSSQSVLKQIKKNRKEA
HHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIASILVLMVTLISLGSVFMLVFEGQNPNANIQTAGDAIWWAFVTISTVGYGDHYPITVA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCHHHH
GKILAVFIIISGVGIFGMISGLITSIITEPEKVREKHMHEQEQIVRSQKLDLLLQQQTEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LERLNQIENNKEK
HHHHHHHHCCCCC
>Mature Secondary Structure
MNHTKIDLKPMSLMSLILSFLSLIVISSLLFLPLNSASKAMLIGIDTTICALFLLQLSID
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHH
LLRSQDRRQYMKDHWIDFIASIPIIEPIRYARIFHILRICRLFRSSQSVLKQIKKNRKEA
HHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIASILVLMVTLISLGSVFMLVFEGQNPNANIQTAGDAIWWAFVTISTVGYGDHYPITVA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCHHHH
GKILAVFIIISGVGIFGMISGLITSIITEPEKVREKHMHEQEQIVRSQKLDLLLQQQTEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LERLNQIENNKEK
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]