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The map label for this gene is rpiA

Identifier: 209695960

GI number: 209695960

Start: 2722637

End: 2723293

Strand: Direct

Name: rpiA

Synonym: VSAL_I2542

Alternate gene names: 209695960

Gene position: 2722637-2723293 (Clockwise)

Preceding gene: 209695959

Following gene: 209695961

Centisome position: 81.88

GC content: 41.25

Gene sequence:

>657_bases
ATGACTCAAGACGAGATGAAAAAAGCAGCCGGTTGGGCAGCGTTAGAATACGTAGAAGTTGGCAGCATTGTTGGTGTAGG
TACAGGATCAACAGTAAATCATTTCATCGACGCACTTGCGACAATGAAAGATGACATTAAAGGTGCGGTATCAAGTTCAG
TTGCTTCAACAGAAAAACTAAAAGAACTCGGTATTGAAGTTTTTGATTGTAACGATGTTGCTGGTCTTGATGTTTATGTC
GATGGCGCGGATGAAATCAATGGTCTGAACGAGATGATTAAAGGTGGTGGTGCAGCCCTTACTCGTGAAAAAATCGTTGC
TGCAATTTCTGATAAGTTTATTTGTATTGTTGATAACACAAAACAAGTCGACATATTAGGTGAGTTTCCTCTTCCTGTTG
AAGTCATTCCAATGGCACGCTCTTATGTTGCTCGTGAACTGGTTAAGTTAGGTGGTGATCCTGCCTACCGTGAAGGCGTT
GTTACTGATAATGGTAATATGATCTTAGACGTTCACAACATGAAAATCACCAATGCGAAAGAGCTTGAAGATAAAATTAA
TGCCCTTCCTGGTGTTGTGACGGTTGGTTTATTTGCTCACCGTGGCGCCGATGTTTTATTGGTTGGCGCTCCTGATGGCG
TAAAAAAATTCGTTTAA

Upstream 100 bases:

>100_bases
TTTACTCTTTCTAGACTTATTTTTTCTGACGAAGAAAAATCTGTACGTTATAATCACGCCGCTTTCATATTGAACACTAT
TATTTCATTAGGAGAATGTC

Downstream 100 bases:

>100_bases
TACGATGATTCCCCTTCTTATCTCTGTAAATTGAGAGATAAAAATGTCATTTGATTACAAACGGTGCTCATTAGCACCGT
TTTTTATTAACTAACCTGAA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDEMKKAAGWAALEYVEVGSIVGVGTGSTVNHFIDALATMKDDIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYV
DGADEINGLNEMIKGGGAALTREKIVAAISDKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARELVKLGGDPAYREGV
VTDNGNMILDVHNMKITNAKELEDKINALPGVVTVGLFAHRGADVLLVGAPDGVKKFV

Sequences:

>Translated_218_residues
MTQDEMKKAAGWAALEYVEVGSIVGVGTGSTVNHFIDALATMKDDIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYV
DGADEINGLNEMIKGGGAALTREKIVAAISDKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARELVKLGGDPAYREGV
VTDNGNMILDVHNMKITNAKELEDKINALPGVVTVGLFAHRGADVLLVGAPDGVKKFV
>Mature_217_residues
TQDEMKKAAGWAALEYVEVGSIVGVGTGSTVNHFIDALATMKDDIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYVD
GADEINGLNEMIKGGGAALTREKIVAAISDKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARELVKLGGDPAYREGVV
TDNGNMILDVHNMKITNAKELEDKINALPGVVTVGLFAHRGADVLLVGAPDGVKKFV

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=35.7142857142857, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789280, Length=218, Percent_Identity=74.3119266055046, Blast_Score=330, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=35.981308411215, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=29.7777777777778, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364072, Length=201, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_ALISL (B6EKP6)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263890.1
- ProteinModelPortal:   B6EKP6
- GeneID:   6987808
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2542
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23077; Mature: 22946

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALEYVEVGSIVGVGTGSTVNHFIDALATMKDDIKGAVSSSVASTEKL
CCHHHHHHHHCHHHHHHEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELGIEVFDCNDVAGLDVYVDGADEINGLNEMIKGGGAALTREKIVAAISDKFICIVDNT
HHCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
KQVDILGEFPLPVEVIPMARSYVARELVKLGGDPAYREGVVTDNGNMILDVHNMKITNAK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEEECEEECCHH
ELEDKINALPGVVTVGLFAHRGADVLLVGAPDGVKKFV
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCHHHHCC
>Mature Secondary Structure 
TQDEMKKAAGWAALEYVEVGSIVGVGTGSTVNHFIDALATMKDDIKGAVSSSVASTEKL
CHHHHHHHHCHHHHHHEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELGIEVFDCNDVAGLDVYVDGADEINGLNEMIKGGGAALTREKIVAAISDKFICIVDNT
HHCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
KQVDILGEFPLPVEVIPMARSYVARELVKLGGDPAYREGVVTDNGNMILDVHNMKITNAK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEEECEEECCHH
ELEDKINALPGVVTVGLFAHRGADVLLVGAPDGVKKFV
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA