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The map label for this gene is ppnK [H]

Identifier: 209695894

GI number: 209695894

Start: 2649080

End: 2649973

Strand: Direct

Name: ppnK [H]

Synonym: VSAL_I2474

Alternate gene names: 209695894

Gene position: 2649080-2649973 (Clockwise)

Preceding gene: 209695889

Following gene: 209695895

Centisome position: 79.67

GC content: 39.6

Gene sequence:

>894_bases
ATGATGGATATGAAAACAGCTTTTAACGTTATAGCAATCATTGGTAAACCTAGAGACCCTAATGCCATAAAAACGCATTT
AGCCTTATACGATTGGCTTACTGAGCTAAATTATACGGTTTTATTGGATGAGCGTTTACGTGAAGCTCTGCCTACTATAC
CTGATGAATGCTTTAACCATCTTCCTAAACTTGGTGAGTTAGCCGATCTTGCAATTGTTGTTGGTGGTGATGGGAACATG
CTCGGCGCGGCACGTGTATTATCACGCTTTGATATTTCCGTTATTGGCGTAAATAGAGGGAACCTTGGGTTTTTAACCGA
TCTTGACCCTGATAATTTTAAAGAGCCATTAACTGAAGTATTAAATGGCGAATTCATAAAAGAAGAACGTTTCTTACTTG
AATCTGAAGTTCACCGCCATGGACAATTAAAAAGTCACAATTCAGCGTTTAATGAAGTTGTCCTTCACCCTGGACAAGTG
GCACATATGATTGAATTTGAAGTCTATATTGATGATAGCTTTGCGTTCTCTCAACGCTCTGATGGCTTGATTATTTCAAC
CCCAACAGGATCAACCGCTTATTCTTTGTCTGGCGGTGGTCCAATCCTTTCTCCTAATTTAAATGCCATTTCAATTGTTC
CTATGTTTCCACATACGCTTTCAAGTCGACCTTTAGTCGTTGAGGGAGGCCGCCATATTAAATTATTAGTTTCCCCAGAT
AATCGCAGTTCACTTGAAGTCAGTTGTGATGGACAAGTCTCTTTACCAGTTAGCCCAGGTGACGAAGTTCATATTTTCCA
AAGCCCAGGCAAGTTGCAACTTATCCACCCCAAAGATTATATCTACTATCATGTACTTAGAAATAAGTTAGGCTGGTCTA
GTAAGCTTTTCTAA

Upstream 100 bases:

>100_bases
CTACAAGCAAATTAAAACTTTGTCATTATTATGGGGACTAAATAAAGCGATTCAAGCATAATAGTATTAATTGTAACATT
TGTTCCCCATTTAATGATGG

Downstream 100 bases:

>100_bases
AAACCATAATCTTAAATCATAAGCGATTCACAAAAAATTCAAATAAACTTTACTGTATAAAGAAACAGTATATACTGTTT
CTTTATACAGTACTTTAGTG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MMDMKTAFNVIAIIGKPRDPNAIKTHLALYDWLTELNYTVLLDERLREALPTIPDECFNHLPKLGELADLAIVVGGDGNM
LGAARVLSRFDISVIGVNRGNLGFLTDLDPDNFKEPLTEVLNGEFIKEERFLLESEVHRHGQLKSHNSAFNEVVLHPGQV
AHMIEFEVYIDDSFAFSQRSDGLIISTPTGSTAYSLSGGGPILSPNLNAISIVPMFPHTLSSRPLVVEGGRHIKLLVSPD
NRSSLEVSCDGQVSLPVSPGDEVHIFQSPGKLQLIHPKDYIYYHVLRNKLGWSSKLF

Sequences:

>Translated_297_residues
MMDMKTAFNVIAIIGKPRDPNAIKTHLALYDWLTELNYTVLLDERLREALPTIPDECFNHLPKLGELADLAIVVGGDGNM
LGAARVLSRFDISVIGVNRGNLGFLTDLDPDNFKEPLTEVLNGEFIKEERFLLESEVHRHGQLKSHNSAFNEVVLHPGQV
AHMIEFEVYIDDSFAFSQRSDGLIISTPTGSTAYSLSGGGPILSPNLNAISIVPMFPHTLSSRPLVVEGGRHIKLLVSPD
NRSSLEVSCDGQVSLPVSPGDEVHIFQSPGKLQLIHPKDYIYYHVLRNKLGWSSKLF
>Mature_297_residues
MMDMKTAFNVIAIIGKPRDPNAIKTHLALYDWLTELNYTVLLDERLREALPTIPDECFNHLPKLGELADLAIVVGGDGNM
LGAARVLSRFDISVIGVNRGNLGFLTDLDPDNFKEPLTEVLNGEFIKEERFLLESEVHRHGQLKSHNSAFNEVVLHPGQV
AHMIEFEVYIDDSFAFSQRSDGLIISTPTGSTAYSLSGGGPILSPNLNAISIVPMFPHTLSSRPLVVEGGRHIKLLVSPD
NRSSLEVSCDGQVSLPVSPGDEVHIFQSPGKLQLIHPKDYIYYHVLRNKLGWSSKLF

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=324, Percent_Identity=28.3950617283951, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1788968, Length=294, Percent_Identity=58.843537414966, Blast_Score=355, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=32.6446280991736, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322509, Length=241, Percent_Identity=30.7053941908714, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325068, Length=219, Percent_Identity=31.9634703196347, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573826, Length=317, Percent_Identity=30.5993690851735, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573830, Length=322, Percent_Identity=30.1242236024845, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573828, Length=318, Percent_Identity=30.5031446540881, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161077047, Length=318, Percent_Identity=30.5031446540881, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573832, Length=322, Percent_Identity=30.1242236024845, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24653424, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20129957, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363321, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363323, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24653422, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32863; Mature: 32863

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDMKTAFNVIAIIGKPRDPNAIKTHLALYDWLTELNYTVLLDERLREALPTIPDECFNH
CCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCHHHHHHH
LPKLGELADLAIVVGGDGNMLGAARVLSRFDISVIGVNRGNLGFLTDLDPDNFKEPLTEV
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCHHHHHHHHH
LNGEFIKEERFLLESEVHRHGQLKSHNSAFNEVVLHPGQVAHMIEFEVYIDDSFAFSQRS
HCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCEEEEEEEEEEECCCEEECCCC
DGLIISTPTGSTAYSLSGGGPILSPNLNAISIVPMFPHTLSSRPLVVEGGRHIKLLVSPD
CCEEEECCCCCEEEEECCCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCEEEEEECCC
NRSSLEVSCDGQVSLPVSPGDEVHIFQSPGKLQLIHPKDYIYYHVLRNKLGWSSKLF
CCCEEEEEECCEEEEECCCCCCEEEEECCCCEEEECCCHHEEEEEHHHCCCCCCCCC
>Mature Secondary Structure
MMDMKTAFNVIAIIGKPRDPNAIKTHLALYDWLTELNYTVLLDERLREALPTIPDECFNH
CCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCHHHHHHH
LPKLGELADLAIVVGGDGNMLGAARVLSRFDISVIGVNRGNLGFLTDLDPDNFKEPLTEV
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCHHHHHHHHH
LNGEFIKEERFLLESEVHRHGQLKSHNSAFNEVVLHPGQVAHMIEFEVYIDDSFAFSQRS
HCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCEEEEEEEEEEECCCEEECCCC
DGLIISTPTGSTAYSLSGGGPILSPNLNAISIVPMFPHTLSSRPLVVEGGRHIKLLVSPD
CCEEEECCCCCEEEEECCCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCEEEEEECCC
NRSSLEVSCDGQVSLPVSPGDEVHIFQSPGKLQLIHPKDYIYYHVLRNKLGWSSKLF
CCCEEEEEECCEEEEECCCCCCEEEEECCCCEEEECCCHHEEEEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA