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The map label for this gene is fadE [H]

Identifier: 209695820

GI number: 209695820

Start: 2563944

End: 2566391

Strand: Direct

Name: fadE [H]

Synonym: VSAL_I2395

Alternate gene names: 209695820

Gene position: 2563944-2566391 (Clockwise)

Preceding gene: 209695819

Following gene: 209695824

Centisome position: 77.11

GC content: 42.2

Gene sequence:

>2448_bases
ATGGCCCTCACACTACTAACAACATTAATTGCACTTGCTGCATTAAGTTATCATCGACAATCATTACAAACTGCTACGCT
AGTAACGGCAGCAATTTTGGCGGTGAGTACCGGATTAGGTTATGCCGGCGTTATCACTTGGGCTATTTTTTTAGCAATCG
CGGTACCTCTAAACATCCCTTCAATTAGGCAATCTCTGTTTAGTAATAAAGCCTTATCGATGTTTAAAGGTGTTATGCCT
GAAATGTCAAAAACAGAAAAAGATGCCATTGAAGCGGGTACGGTTTGGTGGGAAGCAGAGCTGTTTAAGGGAAATCCTGA
TTGGAAATTCCTTCATAATATTCCTAAAAATACACTATCCGATGAAGAACAAGCATTCATGGATGGCCCAGTAAACGAAG
TGTGCCGCATGATCAATGATTATGAAGTCACTCATGAGCTTGCTGATTTGCCACCAGAAGTATGGCAATACCTGAAAGAT
AACAAATTCTTTGCCATGATCATTAAGAAAAAATACGGTGGTTTAGAATTCTCAGCTTATGCACAATCTTCTGTTCTACA
AAAATTGACCAGTGTTTCTGGTGTTTTATCTATTACGGTTGGGGTTCCGAATTCATTAGGTCCAGGCGAACTTCTTCAAC
ATTACGGTACTGAAGATCAAAAAAATCATTATTTACCTAGCTTAGCCGAAGGTAAGGAAATCCCATGTTTTGCACTAACT
AGCCCAGAAGCGGGCTCCGATGCAGGGTCAATTCCTGATTTTGGTATCGTGACAAAAGGCATGTGGGAAGGTAAAGAAGT
ACTAGGTATGCGCCTTACTTGGAATAAGCGTTACATTACCCTAGCCCCTGTCGCTACCGTTTTAGGTTTGGCGTTTAAAT
TACAAGATCCTGATGGTTTATTAGGCGATAAGAAAAACCTAGGCATTACTTGTGCTCTTATTCCAACAAACTTAGAAGGC
GTTAAAATTGGACGCCGCCATTTCCCTATGAATGTTCCATTTCAAAATGGTCCAACACAAGGTGACGATTTATTTGTTCC
ACTTGATTACATCATCGGTGGTGAAAAAATGGCAGGTCACGGTTGGCGCATGCTGGTTGAATGTCTGTCTGTGGGTCGAG
GAATCACCTTACCATCCAATGCAACGGGTGGCGCAAAAACGGCCGCACTCGCTACGGGAGCTTATGCACGAATTCGTCGC
CAATTCAAATTACCCATTGGTAAAATGGAAGGGATTGAAGAGCCATTAGCGCGTATGGCTGGTAATGCTTACATGATGGA
CGCAGCAAGTGCGCTAACGGTTGCTGGTATTGTGCAAGGCGAGAAGCCATCGGTTATCTCTGCCATTGTAAAATATCACT
GTACCCACCGTGCACAACGTATTGCCATTGATGGTATGGACATCGCTGGTGGTAAAGGGATCTGTCTAGGCAGTTCTAAT
TTCTTGGCGCGCAGTTATCAAGGTTCACCAATCGCCATTACCGTTGAAGGCGCAAACATACTAACCCGTTCAATGATTAT
CTACGGTCAAGGTGCTATTCGCTGCCACCCTTATGTTCTTGAAGAAATGGACGCGGCCTACTTAGAAGATAAGCAAGCGT
CTCTTGATAAATTCGATGCTGCTGTCTTTGGTCATATTGGCTTTGGGATCAGTAATTTTGTACGCAGTTTATGGTTTGGC
CTAACCGATGGTCGTGGTTCAAAAACCGCCTTTAACGATGAAACCAAACGTTATTACCAACAAGTAAATCGTTATAGTAC
GAACTTAGCATTACTATCTGATGTATCAATGGCTGTTCTTGGCGGCAGTTTGAAGCGCCGTGAACGCATGTCAGCACGTC
TAGGTGACATTTTAAGTCAACTGTATCTAACAACGTCAGTACTTAAGCGTTTTGATGATGAAGGTCGTCAGAAGGAAGAT
TTACCATTAGTACATTGGAGCGTGCAAGATTCGTTACATCAAGCAGAGCAAGCGATTGATGGGTTATTAAGTAATTTCCC
AAATCAATTTATCGCCAAAGCAATGCGTTTAATCCTGCTTCCAACCGGGCTTCGTCGTCAACGCCCAAGTGATAAACTGG
ATCATAAATTAGCTCGAATTCTTCAAGAGCCATCAGGAGTCCGTAGTCGAATTGGTCGAGGTCTGTTCTTAGAGGCGAGT
CGCTTTAATCCGGTAGGTAAAATGGAAGAAGCACTGATTGATATCTTAACCGCAGAACCAATTTATGATCGTGTATGTAA
AGAATCAAAACAACGTCTACCCTTCATGCAATTAGATCGTGTTGCAAAAATCGGTTTAGAGTTAAATATTATTTCAGATA
AAGAAGCCCTACTACTTCGTAAAGCAGAGAAAAGTCGACTAGCGACGATTAGTGTTGAAGATTTTGACCCAAGTGAGCTT
ATCGTAAAGCCAGAAGTTAATCATTTTGAACACAGTAAAATTGCTTAG

Upstream 100 bases:

>100_bases
CTTATCAGAAAGAGCTTTAAACAAACAATAACATTACGACCGAGTATCGTAATCAATTCTGTTCCTACAAACAGAAACAG
CGCCGGAAAAGGAGAATCAC

Downstream 100 bases:

>100_bases
TTAATTCTCTTATCTAAAACATAAAAAAGGCCAGAACATGAACTGTTCTGGCCTTTTTATTTTCTATATACATCTTATTT
ATTTAAGGCTGACGACTAAC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MALTLLTTLIALAALSYHRQSLQTATLVTAAILAVSTGLGYAGVITWAIFLAIAVPLNIPSIRQSLFSNKALSMFKGVMP
EMSKTEKDAIEAGTVWWEAELFKGNPDWKFLHNIPKNTLSDEEQAFMDGPVNEVCRMINDYEVTHELADLPPEVWQYLKD
NKFFAMIIKKKYGGLEFSAYAQSSVLQKLTSVSGVLSITVGVPNSLGPGELLQHYGTEDQKNHYLPSLAEGKEIPCFALT
SPEAGSDAGSIPDFGIVTKGMWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLQDPDGLLGDKKNLGITCALIPTNLEG
VKIGRRHFPMNVPFQNGPTQGDDLFVPLDYIIGGEKMAGHGWRMLVECLSVGRGITLPSNATGGAKTAALATGAYARIRR
QFKLPIGKMEGIEEPLARMAGNAYMMDAASALTVAGIVQGEKPSVISAIVKYHCTHRAQRIAIDGMDIAGGKGICLGSSN
FLARSYQGSPIAITVEGANILTRSMIIYGQGAIRCHPYVLEEMDAAYLEDKQASLDKFDAAVFGHIGFGISNFVRSLWFG
LTDGRGSKTAFNDETKRYYQQVNRYSTNLALLSDVSMAVLGGSLKRRERMSARLGDILSQLYLTTSVLKRFDDEGRQKED
LPLVHWSVQDSLHQAEQAIDGLLSNFPNQFIAKAMRLILLPTGLRRQRPSDKLDHKLARILQEPSGVRSRIGRGLFLEAS
RFNPVGKMEEALIDILTAEPIYDRVCKESKQRLPFMQLDRVAKIGLELNIISDKEALLLRKAEKSRLATISVEDFDPSEL
IVKPEVNHFEHSKIA

Sequences:

>Translated_815_residues
MALTLLTTLIALAALSYHRQSLQTATLVTAAILAVSTGLGYAGVITWAIFLAIAVPLNIPSIRQSLFSNKALSMFKGVMP
EMSKTEKDAIEAGTVWWEAELFKGNPDWKFLHNIPKNTLSDEEQAFMDGPVNEVCRMINDYEVTHELADLPPEVWQYLKD
NKFFAMIIKKKYGGLEFSAYAQSSVLQKLTSVSGVLSITVGVPNSLGPGELLQHYGTEDQKNHYLPSLAEGKEIPCFALT
SPEAGSDAGSIPDFGIVTKGMWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLQDPDGLLGDKKNLGITCALIPTNLEG
VKIGRRHFPMNVPFQNGPTQGDDLFVPLDYIIGGEKMAGHGWRMLVECLSVGRGITLPSNATGGAKTAALATGAYARIRR
QFKLPIGKMEGIEEPLARMAGNAYMMDAASALTVAGIVQGEKPSVISAIVKYHCTHRAQRIAIDGMDIAGGKGICLGSSN
FLARSYQGSPIAITVEGANILTRSMIIYGQGAIRCHPYVLEEMDAAYLEDKQASLDKFDAAVFGHIGFGISNFVRSLWFG
LTDGRGSKTAFNDETKRYYQQVNRYSTNLALLSDVSMAVLGGSLKRRERMSARLGDILSQLYLTTSVLKRFDDEGRQKED
LPLVHWSVQDSLHQAEQAIDGLLSNFPNQFIAKAMRLILLPTGLRRQRPSDKLDHKLARILQEPSGVRSRIGRGLFLEAS
RFNPVGKMEEALIDILTAEPIYDRVCKESKQRLPFMQLDRVAKIGLELNIISDKEALLLRKAEKSRLATISVEDFDPSEL
IVKPEVNHFEHSKIA
>Mature_814_residues
ALTLLTTLIALAALSYHRQSLQTATLVTAAILAVSTGLGYAGVITWAIFLAIAVPLNIPSIRQSLFSNKALSMFKGVMPE
MSKTEKDAIEAGTVWWEAELFKGNPDWKFLHNIPKNTLSDEEQAFMDGPVNEVCRMINDYEVTHELADLPPEVWQYLKDN
KFFAMIIKKKYGGLEFSAYAQSSVLQKLTSVSGVLSITVGVPNSLGPGELLQHYGTEDQKNHYLPSLAEGKEIPCFALTS
PEAGSDAGSIPDFGIVTKGMWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLQDPDGLLGDKKNLGITCALIPTNLEGV
KIGRRHFPMNVPFQNGPTQGDDLFVPLDYIIGGEKMAGHGWRMLVECLSVGRGITLPSNATGGAKTAALATGAYARIRRQ
FKLPIGKMEGIEEPLARMAGNAYMMDAASALTVAGIVQGEKPSVISAIVKYHCTHRAQRIAIDGMDIAGGKGICLGSSNF
LARSYQGSPIAITVEGANILTRSMIIYGQGAIRCHPYVLEEMDAAYLEDKQASLDKFDAAVFGHIGFGISNFVRSLWFGL
TDGRGSKTAFNDETKRYYQQVNRYSTNLALLSDVSMAVLGGSLKRRERMSARLGDILSQLYLTTSVLKRFDDEGRQKEDL
PLVHWSVQDSLHQAEQAIDGLLSNFPNQFIAKAMRLILLPTGLRRQRPSDKLDHKLARILQEPSGVRSRIGRGLFLEASR
FNPVGKMEEALIDILTAEPIYDRVCKESKQRLPFMQLDRVAKIGLELNIISDKEALLLRKAEKSRLATISVEDFDPSELI
VKPEVNHFEHSKIA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=547, Percent_Identity=25.9597806215722, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI4557235, Length=403, Percent_Identity=25.3101736972705, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI76496475, Length=382, Percent_Identity=25.6544502617801, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=25.8152173913043, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI226958412, Length=327, Percent_Identity=24.4648318042813, Blast_Score=68, Evalue=5e-11,
Organism=Homo sapiens, GI226958414, Length=327, Percent_Identity=24.4648318042813, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87081702, Length=807, Percent_Identity=67.2862453531598, Blast_Score=1134, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985184, Length=539, Percent_Identity=24.6753246753247, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=358, Percent_Identity=24.5810055865922, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=335, Percent_Identity=25.3731343283582, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=312, Percent_Identity=27.2435897435897, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=325, Percent_Identity=24, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534353, Length=310, Percent_Identity=25.4838709677419, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=26.5714285714286, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646207, Length=299, Percent_Identity=27.0903010033445, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920834, Length=311, Percent_Identity=29.5819935691318, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356377, Length=391, Percent_Identity=24.0409207161125, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=328, Percent_Identity=26.219512195122, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89612; Mature: 89480

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLLTTLIALAALSYHRQSLQTATLVTAAILAVSTGLGYAGVITWAIFLAIAVPLNIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCH
SIRQSLFSNKALSMFKGVMPEMSKTEKDAIEAGTVWWEAELFKGNPDWKFLHNIPKNTLS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHCCCCCCC
DEEQAFMDGPVNEVCRMINDYEVTHELADLPPEVWQYLKDNKFFAMIIKKKYGGLEFSAY
CHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEHHCCCCEEHHH
AQSSVLQKLTSVSGVLSITVGVPNSLGPGELLQHYGTEDQKNHYLPSLAEGKEIPCFALT
HHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
SPEAGSDAGSIPDFGIVTKGMWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLQDPDGL
CCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCEEEHHHHHHHHHHHEEECCCCCC
LGDKKNLGITCALIPTNLEGVKIGRRHFPMNVPFQNGPTQGDDLFVPLDYIIGGEKMAGH
CCCCCCCCEEEEEECCCCCCEEECHHCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCC
GWRMLVECLSVGRGITLPSNATGGAKTAALATGAYARIRRQFKLPIGKMEGIEEPLARMA
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHC
GNAYMMDAASALTVAGIVQGEKPSVISAIVKYHCTHRAQRIAIDGMDIAGGKGICLGSSN
CCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECCCEECCCCEEEECCCC
FLARSYQGSPIAITVEGANILTRSMIIYGQGAIRCHPYVLEEMDAAYLEDKQASLDKFDA
HHHCCCCCCCEEEEEECCHHHHHEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
AVFGHIGFGISNFVRSLWFGLTDGRGSKTAFNDETKRYYQQVNRYSTNLALLSDVSMAVL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GGSLKRRERMSARLGDILSQLYLTTSVLKRFDDEGRQKEDLPLVHWSVQDSLHQAEQAID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHH
GLLSNFPNQFIAKAMRLILLPTGLRRQRPSDKLDHKLARILQEPSGVRSRIGRGLFLEAS
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEC
RFNPVGKMEEALIDILTAEPIYDRVCKESKQRLPFMQLDRVAKIGLELNIISDKEALLLR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCHHHHHH
KAEKSRLATISVEDFDPSELIVKPEVNHFEHSKIA
HHCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
ALTLLTTLIALAALSYHRQSLQTATLVTAAILAVSTGLGYAGVITWAIFLAIAVPLNIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCH
SIRQSLFSNKALSMFKGVMPEMSKTEKDAIEAGTVWWEAELFKGNPDWKFLHNIPKNTLS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHCCCCCCC
DEEQAFMDGPVNEVCRMINDYEVTHELADLPPEVWQYLKDNKFFAMIIKKKYGGLEFSAY
CHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEHHCCCCEEHHH
AQSSVLQKLTSVSGVLSITVGVPNSLGPGELLQHYGTEDQKNHYLPSLAEGKEIPCFALT
HHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
SPEAGSDAGSIPDFGIVTKGMWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLQDPDGL
CCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCEEEHHHHHHHHHHHEEECCCCCC
LGDKKNLGITCALIPTNLEGVKIGRRHFPMNVPFQNGPTQGDDLFVPLDYIIGGEKMAGH
CCCCCCCCEEEEEECCCCCCEEECHHCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCC
GWRMLVECLSVGRGITLPSNATGGAKTAALATGAYARIRRQFKLPIGKMEGIEEPLARMA
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHC
GNAYMMDAASALTVAGIVQGEKPSVISAIVKYHCTHRAQRIAIDGMDIAGGKGICLGSSN
CCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECCCEECCCCEEEECCCC
FLARSYQGSPIAITVEGANILTRSMIIYGQGAIRCHPYVLEEMDAAYLEDKQASLDKFDA
HHHCCCCCCCEEEEEECCHHHHHEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
AVFGHIGFGISNFVRSLWFGLTDGRGSKTAFNDETKRYYQQVNRYSTNLALLSDVSMAVL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GGSLKRRERMSARLGDILSQLYLTTSVLKRFDDEGRQKEDLPLVHWSVQDSLHQAEQAID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHH
GLLSNFPNQFIAKAMRLILLPTGLRRQRPSDKLDHKLARILQEPSGVRSRIGRGLFLEAS
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEC
RFNPVGKMEEALIDILTAEPIYDRVCKESKQRLPFMQLDRVAKIGLELNIISDKEALLLR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCHHHHHH
KAEKSRLATISVEDFDPSELIVKPEVNHFEHSKIA
HHCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]