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The map label for this gene is cheB [H]

Identifier: 209695718

GI number: 209695718

Start: 2458713

End: 2459855

Strand: Reverse

Name: cheB [H]

Synonym: VSAL_I2286

Alternate gene names: 209695718

Gene position: 2459855-2458713 (Counterclockwise)

Preceding gene: 209695719

Following gene: 209695717

Centisome position: 73.98

GC content: 43.74

Gene sequence:

>1143_bases
ATGGCAATAAAAGTATTAGTTGTTGATGATTCAAGCTTTTTTCGACGTCGAGTGAGTGAAATTATCAACTCAGATCCACG
CCTTGAAGTCATCGATGTAGCAACAAACGGCAAAGAAGCCGTTGAAAAAGCACAATCTTTAAAGCCAGATGTTATCACCA
TGGATATAGAGATGCCTGTTATGGACGGTATCTCAGCAGTTCGAGAAATCATGAAAGTGTGCCCAACACCAACTTTGATG
TTTTCTTCGTTAACTCATGATGGTGCAAAAGCGACATTAGATGCGTTAGATGCGGGTGCATTGGATTTCTTACCAAAGAA
ATTTGAAGATATCGCCCGTAATCGTGATGAGGCGGTTTCATTGCTTCAACAGCGCATTGTTGAGATTGCACGTAAGAAAT
TGTTTATGCGTCGACCTGCTTTAGCTACTCAAGTGACTAAAACTGAGCCTAGAGCAGCGGCAACAACAAGAGTAACTGCG
TCACGAATTACATCGCCAATGAGCGCTGAACCAGTAAAAGCAGTGCCAAGTGCACCTATTGGTCAACGCTTTAAAGCAAC
GGGTAAAAAATATCAGCTAACCGCAATAGGGACTTCAACCGGAGGCCCTGTGGCATTACAAAAGATATTAACGGCACTTC
CTGCTAATTACCCACATCCGATTATTTTAGTTCAGCATATGCCAGCAACGTTTACTGCTGCGTTTGCCGCTCGATTAAAT
AACTTATGTAAGATCCAAGTGAAAGAAGCGCAAGATGGCGATATTTTAAAGCCGGGTTGTGCGTATTTGGCTCCAGGTGG
CTTACAAATGATGATTGATGGTCGTCCTGGTTCTTCTCGTTTGAAGATCCTTGATGGTGGTGAACGCATGAATTACAAAC
CATGTGTTGATGTGACTTTTGGCTCCGCCGCGAAAGTGTATGGCGATAAAGTATTGTCTATGATCTTAACGGGTATGGGA
GCGGATGGTCGTGAAGGCTGTCGTATGCTTAAAGCTGCTGGCGCAACCATTTGGTCTCAAGATGAGCAAAGTTGTGTTGT
CTATGGCATGCCACAAGCCGTCGATAAAGCCGGTTTGTCTTCAGAAAGTTTGCCGATAGAACGTGTCGCTGAACGAATGC
TTGTTGAAGTTGGATTAAAGTAG

Upstream 100 bases:

>100_bases
TGCAACCATCACTTCAGATGGTCACATCGCACTTATTCTTGATGTTCCAAACTTGCTTAAGCGTTATGCAGTACGTATGC
ATTAATGCACAAGGATTGAC

Downstream 100 bases:

>100_bases
GAAAACCGAATGATTGTCTGGAGCATAGCAAACCAGAAAGGTGGTGTGGGTAAAACAACCACAACAATTACACTGGCTGG
TTTATTAAATGAACGTGGTA

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MAIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVATNGKEAVEKAQSLKPDVITMDIEMPVMDGISAVREIMKVCPTPTLM
FSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVSLLQQRIVEIARKKLFMRRPALATQVTKTEPRAAATTRVTA
SRITSPMSAEPVKAVPSAPIGQRFKATGKKYQLTAIGTSTGGPVALQKILTALPANYPHPIILVQHMPATFTAAFAARLN
NLCKIQVKEAQDGDILKPGCAYLAPGGLQMMIDGRPGSSRLKILDGGERMNYKPCVDVTFGSAAKVYGDKVLSMILTGMG
ADGREGCRMLKAAGATIWSQDEQSCVVYGMPQAVDKAGLSSESLPIERVAERMLVEVGLK

Sequences:

>Translated_380_residues
MAIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVATNGKEAVEKAQSLKPDVITMDIEMPVMDGISAVREIMKVCPTPTLM
FSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVSLLQQRIVEIARKKLFMRRPALATQVTKTEPRAAATTRVTA
SRITSPMSAEPVKAVPSAPIGQRFKATGKKYQLTAIGTSTGGPVALQKILTALPANYPHPIILVQHMPATFTAAFAARLN
NLCKIQVKEAQDGDILKPGCAYLAPGGLQMMIDGRPGSSRLKILDGGERMNYKPCVDVTFGSAAKVYGDKVLSMILTGMG
ADGREGCRMLKAAGATIWSQDEQSCVVYGMPQAVDKAGLSSESLPIERVAERMLVEVGLK
>Mature_379_residues
AIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVATNGKEAVEKAQSLKPDVITMDIEMPVMDGISAVREIMKVCPTPTLMF
SSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVSLLQQRIVEIARKKLFMRRPALATQVTKTEPRAAATTRVTAS
RITSPMSAEPVKAVPSAPIGQRFKATGKKYQLTAIGTSTGGPVALQKILTALPANYPHPIILVQHMPATFTAAFAARLNN
LCKIQVKEAQDGDILKPGCAYLAPGGLQMMIDGRPGSSRLKILDGGERMNYKPCVDVTFGSAAKVYGDKVLSMILTGMGA
DGREGCRMLKAAGATIWSQDEQSCVVYGMPQAVDKAGLSSESLPIERVAERMLVEVGLK

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=375, Percent_Identity=35.7333333333333, Blast_Score=224, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 40959; Mature: 40828

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVATNGKEAVEKAQSLKPDVITMDIEMPV
CEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCH
MDGISAVREIMKVCPTPTLMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVS
HHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LLQQRIVEIARKKLFMRRPALATQVTKTEPRAAATTRVTASRITSPMSAEPVKAVPSAPI
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GQRFKATGKKYQLTAIGTSTGGPVALQKILTALPANYPHPIILVQHMPATFTAAFAARLN
CCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHC
NLCKIQVKEAQDGDILKPGCAYLAPGGLQMMIDGRPGSSRLKILDGGERMNYKPCVDVTF
CEEEEEEECCCCCCCCCCCCHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEC
GSAAKVYGDKVLSMILTGMGADGREGCRMLKAAGATIWSQDEQSCVVYGMPQAVDKAGLS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHCCCC
SESLPIERVAERMLVEVGLK
CCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVATNGKEAVEKAQSLKPDVITMDIEMPV
EEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCH
MDGISAVREIMKVCPTPTLMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVS
HHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LLQQRIVEIARKKLFMRRPALATQVTKTEPRAAATTRVTASRITSPMSAEPVKAVPSAPI
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GQRFKATGKKYQLTAIGTSTGGPVALQKILTALPANYPHPIILVQHMPATFTAAFAARLN
CCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHC
NLCKIQVKEAQDGDILKPGCAYLAPGGLQMMIDGRPGSSRLKILDGGERMNYKPCVDVTF
CEEEEEEECCCCCCCCCCCCHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEC
GSAAKVYGDKVLSMILTGMGADGREGCRMLKAAGATIWSQDEQSCVVYGMPQAVDKAGLS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHCCCC
SESLPIERVAERMLVEVGLK
CCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA