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The map label for this gene is ycfH [C]

Identifier: 209695683

GI number: 209695683

Start: 2417190

End: 2417960

Strand: Direct

Name: ycfH [C]

Synonym: VSAL_I2247

Alternate gene names: 209695683

Gene position: 2417190-2417960 (Clockwise)

Preceding gene: 209695682

Following gene: 209695684

Centisome position: 72.69

GC content: 37.74

Gene sequence:

>771_bases
GTGTTAATTGATTCACACTGTCACCTTGATAAATTAAATTATGATGATCTGCATGTTAGTGTCGGTGATGTTATAGAAAA
AGCAAAACAACGTGGGGTTAGTCAGTTTTTAACGGTAGGCGTTACGCTTGATGCTTTTCCAAATATGATGGAAATGATTG
AAGACCATCCAGAAGTTCATGCTTCTTGTGGCATCCACCCACTTGATGTTGAATCTAATTTCGACTTAGCGCTTTTCCGT
GAGTACGCATCAAATAAAAGAGTGATTGCGATTGGTGAAACAGGGCTTGATTACTTTTATCAGCCAGAAACAGCAGAAAG
ACAGCGTGACTTGTTTACCCAACAAGTAGATGTTGCTGTTGAATATAATAAACCTCTTATTATCCATACTCGCCAAGCAA
GAGAAGACACATTAGCGATTTTAAAAAATGGTCATGCTGAAAAGTGTGGTGGGGTGATACATTGTTTTACTGAAGATTGG
GCATTTGCTCAAGCGGCAATTGAACTTGGGTTTTATATCTCTATTTCTGGGATTGTTACTTTTAATAAAGCTTCTGAATT
AAAAGATATAGTGCGTCGCTTACCTCTGGATAGGTTATTAGTTGAAACGGATTCTCCGTATTTAGCACCGGTACCTTACC
GTGGTAAAGAAAACCAACCTGCCTATGTGAAAGAAGTCGCAGAGTATATTGCGCTGTTAAAATCGACTTCAGTTGAAGAC
GTTGCGGAAAACACGACAAATAATTTTAAAAATCTTTTTTTGAAACGATAA

Upstream 100 bases:

>100_bases
TTATCATTAAATGAGTTGCGACAACAGTTAAATAGTCATCCTGGATTGAATAAAGAATTATTAATTACTCAATGGTTATT
TGAGTTTATTGGAGCGTAAT

Downstream 100 bases:

>100_bases
ATAGCATTTGTTGATAAAGCAATCAAAAGGGAGGGAATTACCTCTCTTTTTTTTTGTAAATTGATTTAATACAGGTTTAT
GTAACTATTTTACTAAGTAA

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLIDSHCHLDKLNYDDLHVSVGDVIEKAKQRGVSQFLTVGVTLDAFPNMMEMIEDHPEVHASCGIHPLDVESNFDLALFR
EYASNKRVIAIGETGLDYFYQPETAERQRDLFTQQVDVAVEYNKPLIIHTRQAREDTLAILKNGHAEKCGGVIHCFTEDW
AFAQAAIELGFYISISGIVTFNKASELKDIVRRLPLDRLLVETDSPYLAPVPYRGKENQPAYVKEVAEYIALLKSTSVED
VAENTTNNFKNLFLKR

Sequences:

>Translated_256_residues
MLIDSHCHLDKLNYDDLHVSVGDVIEKAKQRGVSQFLTVGVTLDAFPNMMEMIEDHPEVHASCGIHPLDVESNFDLALFR
EYASNKRVIAIGETGLDYFYQPETAERQRDLFTQQVDVAVEYNKPLIIHTRQAREDTLAILKNGHAEKCGGVIHCFTEDW
AFAQAAIELGFYISISGIVTFNKASELKDIVRRLPLDRLLVETDSPYLAPVPYRGKENQPAYVKEVAEYIALLKSTSVED
VAENTTNNFKNLFLKR
>Mature_256_residues
MLIDSHCHLDKLNYDDLHVSVGDVIEKAKQRGVSQFLTVGVTLDAFPNMMEMIEDHPEVHASCGIHPLDVESNFDLALFR
EYASNKRVIAIGETGLDYFYQPETAERQRDLFTQQVDVAVEYNKPLIIHTRQAREDTLAILKNGHAEKCGGVIHCFTEDW
AFAQAAIELGFYISISGIVTFNKASELKDIVRRLPLDRLLVETDSPYLAPVPYRGKENQPAYVKEVAEYIALLKSTSVED
VAENTTNNFKNLFLKR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=32.3420074349442, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=32.7137546468402, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=32.1167883211679, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=30.5019305019305, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI225903424, Length=227, Percent_Identity=29.5154185022026, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=30.1310043668122, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI14042943, Length=271, Percent_Identity=24.7232472324723, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=22.8915662650602, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787342, Length=253, Percent_Identity=53.7549407114625, Blast_Score=286, Evalue=7e-79,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=30.1158301158301, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI48994985, Length=239, Percent_Identity=31.3807531380753, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=28.4132841328413, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.4339622641509, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=297, Percent_Identity=27.6094276094276, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330018, Length=279, Percent_Identity=30.4659498207885, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586117, Length=279, Percent_Identity=30.4659498207885, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648690, Length=271, Percent_Identity=29.520295202952, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28977; Mature: 28977

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHCHLDKLNYDDLHVSVGDVIEKAKQRGVSQFLTVGVTLDAFPNMMEMIEDHPEVH
CEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHCEEHHHHHHHHHHHHCCCCHH
ASCGIHPLDVESNFDLALFREYASNKRVIAIGETGLDYFYQPETAERQRDLFTQQVDVAV
HHCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHEEEE
EYNKPLIIHTRQAREDTLAILKNGHAEKCGGVIHCFTEDWAFAQAAIELGFYISISGIVT
ECCCCEEEEECCCCHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHCEEEEEEEEEE
FNKASELKDIVRRLPLDRLLVETDSPYLAPVPYRGKENQPAYVKEVAEYIALLKSTSVED
ECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VAENTTNNFKNLFLKR
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIDSHCHLDKLNYDDLHVSVGDVIEKAKQRGVSQFLTVGVTLDAFPNMMEMIEDHPEVH
CEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHCEEHHHHHHHHHHHHCCCCHH
ASCGIHPLDVESNFDLALFREYASNKRVIAIGETGLDYFYQPETAERQRDLFTQQVDVAV
HHCCCEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHEEEE
EYNKPLIIHTRQAREDTLAILKNGHAEKCGGVIHCFTEDWAFAQAAIELGFYISISGIVT
ECCCCEEEEECCCCHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHCEEEEEEEEEE
FNKASELKDIVRRLPLDRLLVETDSPYLAPVPYRGKENQPAYVKEVAEYIALLKSTSVED
ECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VAENTTNNFKNLFLKR
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]