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The map label for this gene is udk

Identifier: 209695664

GI number: 209695664

Start: 2395269

End: 2395916

Strand: Direct

Name: udk

Synonym: VSAL_I2228

Alternate gene names: 209695664

Gene position: 2395269-2395916 (Clockwise)

Preceding gene: 209695663

Following gene: 209695665

Centisome position: 72.03

GC content: 38.43

Gene sequence:

>648_bases
ATGTCAGAGAACAGTAATCATCACTGTATTATCGTAGGTATTGCAGGGGCATCCGCTTCAGGCAAAAGTCTGATTGCTTC
TACTATTTATAATGAACTACGAGCAAAAGTTGGCGACCACCAAATTGGCGTAATAACTGAAGACAGTTACTACAAGGACC
AAAGCCACCTGACCATGGAAGAAAGAGTCAAAACTAATTATGATCACCCAAATGCATTAGATCATCGATTATTGAGTGAA
CATCTTGAACAATTGATGCGTGGTGAAGCTGTTAACATCCCAACATACAGCTATACAGAGCACACTCGAACATCAGATGT
TGAAGTAATGACACCTAAAAAGGTTATTATTCTTGAAGGTATTTTATTACTAACTGATCCTAGATTACGTAATTTGATGC
ATGCAAGTGTGTTTATGGATACGCCATTAGATATTTGTTTATTACGTCGTGCTAAGCGTGATGTTGAAGAACGTGGTCGT
TCAATGGAATCGGTATTTGAACAATACCAGAAGACTGTCCGCCCAATGTTCATGCAATTTATTGATCCATCAAAGCAACA
TGCCGATATTATTGTCCCTCGTGGCGGTAAAAACCGTATCGCTATTGATGTACTAAAAGCGCATATTTCAAGATTATTGA
AAGCGTAA

Upstream 100 bases:

>100_bases
AGTTAAATTATGAGTGGAAAGTCTTATTTTTAGTCCTTATAATTGAGCGGTTTTATTTAATAAATCTTATCGTATCTCGC
TACACTTTTAGGTATCTTTT

Downstream 100 bases:

>100_bases
ATAATAATAGTTATTAGAACTGGTCGACATTATGTCGGCCTTTTTTTTGTCTCATGCTCTGTAAATTGTCTATATTTAGG
TATATAACTATAAATAACTC

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHRLLSE
HLEQLMRGEAVNIPTYSYTEHTRTSDVEVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRAKRDVEERGR
SMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA

Sequences:

>Translated_215_residues
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHRLLSE
HLEQLMRGEAVNIPTYSYTEHTRTSDVEVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRAKRDVEERGR
SMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
>Mature_214_residues
SENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHRLLSEH
LEQLMRGEAVNIPTYSYTEHTRTSDVEVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRAKRDVEERGRS
MESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI301129207, Length=200, Percent_Identity=39, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI57863312, Length=200, Percent_Identity=39, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI18699734, Length=214, Percent_Identity=35.0467289719626, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=34.7222222222222, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI209863022, Length=153, Percent_Identity=32.0261437908497, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI87082034, Length=211, Percent_Identity=72.0379146919431, Blast_Score=328, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=40.0966183574879, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=40.0966183574879, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71981181, Length=214, Percent_Identity=33.1775700934579, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24649624, Length=213, Percent_Identity=38.4976525821596, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI221458995, Length=214, Percent_Identity=38.3177570093458, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28573516, Length=202, Percent_Identity=37.6237623762376, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28573514, Length=202, Percent_Identity=37.6237623762376, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28573512, Length=202, Percent_Identity=37.6237623762376, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45550449, Length=202, Percent_Identity=37.6237623762376, Blast_Score=150, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_ALISL (B6EIY7)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263593.1
- ProteinModelPortal:   B6EIY7
- GeneID:   6987663
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2228
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24491; Mature: 24359

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTME
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
ERVKTNYDHPNALDHRLLSEHLEQLMRGEAVNIPTYSYTEHTRTSDVEVMTPKKVIILEG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECC
ILLLTDPRLRNLMHASVFMDTPLDICLLRRAKRDVEERGRSMESVFEQYQKTVRPMFMQF
HHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTME
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
ERVKTNYDHPNALDHRLLSEHLEQLMRGEAVNIPTYSYTEHTRTSDVEVMTPKKVIILEG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECC
ILLLTDPRLRNLMHASVFMDTPLDICLLRRAKRDVEERGRSMESVFEQYQKTVRPMFMQF
HHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA