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The map label for this gene is cmk

Identifier: 209695656

GI number: 209695656

Start: 2386625

End: 2387299

Strand: Direct

Name: cmk

Synonym: VSAL_I2219

Alternate gene names: 209695656

Gene position: 2386625-2387299 (Clockwise)

Preceding gene: 209695655

Following gene: 209695657

Centisome position: 71.77

GC content: 43.41

Gene sequence:

>675_bases
ATGACTATTCATTCACCAGTCGTCACTGTTGATGGTCCAAGTGGAGCAGGTAAAGGCACTCTGTGCATGTTACTTGCCGA
AAAGCTAGGTTATAATTTATTAGATTCTGGTGCGATTTATCGCGTATTAGCACTGGCTGCAATTCACCATGGTGTTGATT
TAGGTTCAGAAGAAGGACTTGTTCCTCTTGCTGCTAATCTAGACGTTCAATTTAAAGCTGAAGGTGACTTGGTTAAAGTC
ATCTTAGAAGGCGAAGACGTCTCTTCGGAACTTCGTAAAGAAGAAACTGGTATGGCGGCATCAAAAGTAGCGGCTTTACC
TCAAGTACGTGAAGCGTTATTACGTCGTCAAAGAGCCTTTGCTAGTGCCCCTGGACTTGTCGCTGATGGTCGAGATATGG
GCACTGTTGTATTTACAGGTGCAGAAGTTAAGATATTTTTAGATGCAAGTGCTGAAGAACGTGCGAATCGCCGTATGAAG
CAGTTGCAACAGAAGGGGTTAAATGTTAGATTTGACCGTCTTTTAAGCGAAATCCAAGAGCGTGATGATCGTGACCGCAA
TCGAGCTGTTGCACCATTACGTCCGGCGGAAGACGCTTTGGTACTAGATTCAACGTCAATGAATATTGATGAAGTCGTTG
CTCAGGCACTTACTTTTATTGAATCTAAGCTATAA

Upstream 100 bases:

>100_bases
CAGGGCTTTTTTAGTTTTTAAGAAACTAGAGTATATAAATAATCTGACTTGGGTATAATGCGGCGGTAGAAACCAATCAT
AATAATTAATGGAGAACTCC

Downstream 100 bases:

>100_bases
TTGAAACTTAGTTAGTTTCAAGGATGATAACTAACCTTACTATCAACCCCATGCGGTAGGATACCCATGGACGTTTAATA
ATTGAAGATCAAATTAATGA

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGLVPLAANLDVQFKAEGDLVKV
ILEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAFASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMK
QLQQKGLNVRFDRLLSEIQERDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL

Sequences:

>Translated_224_residues
MTIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGLVPLAANLDVQFKAEGDLVKV
ILEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAFASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMK
QLQQKGLNVRFDRLLSEIQERDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL
>Mature_223_residues
TIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGLVPLAANLDVQFKAEGDLVKVI
LEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAFASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMKQ
LQQKGLNVRFDRLLSEIQERDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=224, Percent_Identity=68.3035714285714, Blast_Score=311, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_ALISL (B6EIX9)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263585.1
- GeneID:   6988258
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2219
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 24191; Mature: 24060

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGL
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
VPLAANLDVQFKAEGDLVKVILEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAF
EEEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
ASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMKQLQQKGLNVRFDRLLSEIQE
HCCCCCEECCCCCCEEEEECCEEEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
RDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL
HCCCHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGL
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
VPLAANLDVQFKAEGDLVKVILEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAF
EEEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
ASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMKQLQQKGLNVRFDRLLSEIQE
HCCCCCEECCCCCCEEEEECCEEEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
RDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL
HCCCHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA