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The map label for this gene is prkA [H]

Identifier: 209695645

GI number: 209695645

Start: 2374331

End: 2376265

Strand: Reverse

Name: prkA [H]

Synonym: VSAL_I2208

Alternate gene names: 209695645

Gene position: 2376265-2374331 (Counterclockwise)

Preceding gene: 209695646

Following gene: 209695644

Centisome position: 71.46

GC content: 39.07

Gene sequence:

>1935_bases
ATGAGTATTTTTGACCACTATCAAGCCCGTTACGAAGCGGCAAAAGATGAAGAGCTTTCACTGCAAGATTTCTTATCACT
ATGTAGTCAGGACAAAAGTGCTTATGCCAATGCAGCAGAAAGACTTTTATTGGCCATTGGTGAGCCCGAAGTCATTGACA
CAGCTCTTGATCCTCAGCTTAGTCGTATATTCTCAAACCGAGTAATTTCTCGCTATGAGACATTCAAAGACTTCTATGGC
ATGGAAGAGCCAATTGAACAAATCGTGTCTTACCTAAAGCATGCTTCTCAAGGCTTAGAAGAGCGCAAACAAATCCTTTA
CTTACTCGGCCCTGTTGGTGGTGGTAAATCATCACTTGCCGAAAAACTAAAAAGTCTCATGCAACAATTGCCAATTTATG
TATTAAGTGCAAATGGCGTTCGTAGTCCTGTAAATGACCATCCTTTCTGCTTATTTGACGTAGCCGAAGATGGGGAACTA
TTAAAAAAAGAATATGGCATTGAGAAGCGAAACCTACGTTCTATTATGTCCCCTTGGGCTGCAAAAAGGTTGCACGAATT
TGGCGGTGACATCACGCAATTTAAAGTGATTAAAGTAAACCCTTCTATTCTTGACCAAATCGGTATTGCTAAAACTGAAC
CAGGTGATGAAAACAACCAAGACATCTCTTCTCTGGTCGGTAAAGTAGACATCCGCCAATTAGAGCATTTCGCCCAAGAT
GACCCCGATGCTTATAGCTATTCAGGATCACTCTGTAAAGCCAACCAAGGTTTAATGGAATTTGTCGAAATGTTTAAAGC
GCCAATTAAAGTGCTACACCCTCTTCTAACGGCAACACAAGAAGGGAACTTTAATGGAACAGAAGGCTTATCAGCATTAC
CTTTTGACGGCATGATTTTAGCTCACTCAAACGAATCAGAATGGCAAACATTCCGAAACAACAAAAACAACGAAGCTTTT
TTAGATCGAGTTTATATCGTTAAAGTCCCATATTGTTTACGTGTTTCTGAAGAAATAAAAATATACCAAAAGCTGCTAGA
ACACAGTGAGTTATCTCAAGCACCTTGCTCACCAAGCACCCTTGGCATCCTAGCTCAATTCACCATACTTTCACGCCTAA
AAGATCCTGAGAATTCATCTCTATTCTCTAAAATGCGTGTTTATGATGGGGAAACATTGAAAGACACGGATCCAAAAGCA
AAAAGCTATCAAGAATATAAAGATTTTGCTGGTGTGGATGAAGGCATGTCAGGCCTATCCACTCGATTCGCTTTCAAAAT
TCTGTCACGCGTATTTAACTTTGACCAAACCGAAGTCGCAGCAAACCCCGTTCACCTTTTTTATGTCATTGAACAACAAA
TTGAACGAGAACAATTCGCTCAAGATGTTGCCGATAAATACACCGAATTTGTGAAAGGTTTTCTTGTACCAAAATACGTT
GAGTTTATTGGTAAAGAAATTCAAACCGCTTACTTAGAATCTTATTCAGAATACGGACAAAACATCTTTGATCGTTACGT
CACTTATGCCGATTTTTGGATCCAAGATCAAGAGTATCGAGATCCAGATACTGGTCAGTTATTTGATCGCTCAGCATTGA
ACGATGAGCTAGAAAAAATAGAAAAAACCGCAGGGATAAGTAATCCTAAAGATTTCCGAAATGAAATTGTTAACTTTGTT
CTTAGAGCAAAAGCCAATAATAACGGCCACAACCCTAAATGGACCAGTTATGAAAAGCTGCGTGTTGTTATTGAGAAAAA
AATGTTCTCAAACACAGAAGACTTACTGCCAGTAATTTCTTTTAACGCGAAAACATCAACAGATGATCAGAAAAAACACG
ATGATTTTGTCGCTCGTATGATGGAAAAAGGGTATACCAAAAAACAAGTTCGTTTACTTGCTGAGTGGTACCTACGCGTT
CGTAAATCTTCATAA

Upstream 100 bases:

>100_bases
ATTTTTATTCTATTTTCGGTTTTTTCTTGGACAAAATAAGGGTTTAGTTACTAACCTTAAGATGTGTAATAAAAAAAACG
GATGACAAGAGGAAATGGAT

Downstream 100 bases:

>100_bases
TCAACCAACAGGACGTTGCAGCCTATATCTCATAGGCTGCCCCTACCAAAATATAGGGGGACATATTATGGCTCAATTTA
TTGATCGAAGATTGAACGGA

Product: PrkA serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MSIFDHYQARYEAAKDEELSLQDFLSLCSQDKSAYANAAERLLLAIGEPEVIDTALDPQLSRIFSNRVISRYETFKDFYG
MEEPIEQIVSYLKHASQGLEERKQILYLLGPVGGGKSSLAEKLKSLMQQLPIYVLSANGVRSPVNDHPFCLFDVAEDGEL
LKKEYGIEKRNLRSIMSPWAAKRLHEFGGDITQFKVIKVNPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAF
LDRVYIVKVPYCLRVSEEIKIYQKLLEHSELSQAPCSPSTLGILAQFTILSRLKDPENSSLFSKMRVYDGETLKDTDPKA
KSYQEYKDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDVADKYTEFVKGFLVPKYV
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFV
LRAKANNNGHNPKWTSYEKLRVVIEKKMFSNTEDLLPVISFNAKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRV
RKSS

Sequences:

>Translated_644_residues
MSIFDHYQARYEAAKDEELSLQDFLSLCSQDKSAYANAAERLLLAIGEPEVIDTALDPQLSRIFSNRVISRYETFKDFYG
MEEPIEQIVSYLKHASQGLEERKQILYLLGPVGGGKSSLAEKLKSLMQQLPIYVLSANGVRSPVNDHPFCLFDVAEDGEL
LKKEYGIEKRNLRSIMSPWAAKRLHEFGGDITQFKVIKVNPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAF
LDRVYIVKVPYCLRVSEEIKIYQKLLEHSELSQAPCSPSTLGILAQFTILSRLKDPENSSLFSKMRVYDGETLKDTDPKA
KSYQEYKDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDVADKYTEFVKGFLVPKYV
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFV
LRAKANNNGHNPKWTSYEKLRVVIEKKMFSNTEDLLPVISFNAKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRV
RKSS
>Mature_643_residues
SIFDHYQARYEAAKDEELSLQDFLSLCSQDKSAYANAAERLLLAIGEPEVIDTALDPQLSRIFSNRVISRYETFKDFYGM
EEPIEQIVSYLKHASQGLEERKQILYLLGPVGGGKSSLAEKLKSLMQQLPIYVLSANGVRSPVNDHPFCLFDVAEDGELL
KKEYGIEKRNLRSIMSPWAAKRLHEFGGDITQFKVIKVNPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQDD
PDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAFL
DRVYIVKVPYCLRVSEEIKIYQKLLEHSELSQAPCSPSTLGILAQFTILSRLKDPENSSLFSKMRVYDGETLKDTDPKAK
SYQEYKDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDVADKYTEFVKGFLVPKYVE
FIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFVL
RAKANNNGHNPKWTSYEKLRVVIEKKMFSNTEDLLPVISFNAKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVR
KSS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=644, Percent_Identity=83.2298136645963, Blast_Score=1151, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73722; Mature: 73591

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFDHYQARYEAAKDEELSLQDFLSLCSQDKSAYANAAERLLLAIGEPEVIDTALDPQL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SRIFSNRVISRYETFKDFYGMEEPIEQIVSYLKHASQGLEERKQILYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQQLPIYVLSANGVRSPVNDHPFCLFDVAEDGELLKKEYGIEKRNLRSIMSPWA
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHH
AKRLHEFGGDITQFKVIKVNPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
HHHHHHHCCCEEEEEEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMIL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
AHSNESEWQTFRNNKNNEAFLDRVYIVKVPYCLRVSEEIKIYQKLLEHSELSQAPCSPST
EECCCHHHHHHHCCCCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LGILAQFTILSRLKDPENSSLFSKMRVYDGETLKDTDPKAKSYQEYKDFAGVDEGMSGLS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDVADKYTEFVKGFLVPKYV
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRSALNDELEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKTAGISNPKDFRNEIVNFVLRAKANNNGHNPKWTSYEKLRVVIEKKMFSNTEDLLPVIS
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHC
FNAKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVRKSS
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIFDHYQARYEAAKDEELSLQDFLSLCSQDKSAYANAAERLLLAIGEPEVIDTALDPQL
CHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SRIFSNRVISRYETFKDFYGMEEPIEQIVSYLKHASQGLEERKQILYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQQLPIYVLSANGVRSPVNDHPFCLFDVAEDGELLKKEYGIEKRNLRSIMSPWA
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHH
AKRLHEFGGDITQFKVIKVNPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
HHHHHHHCCCEEEEEEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMIL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
AHSNESEWQTFRNNKNNEAFLDRVYIVKVPYCLRVSEEIKIYQKLLEHSELSQAPCSPST
EECCCHHHHHHHCCCCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LGILAQFTILSRLKDPENSSLFSKMRVYDGETLKDTDPKAKSYQEYKDFAGVDEGMSGLS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDVADKYTEFVKGFLVPKYV
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRSALNDELEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKTAGISNPKDFRNEIVNFVLRAKANNNGHNPKWTSYEKLRVVIEKKMFSNTEDLLPVIS
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHC
FNAKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVRKSS
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]