Click here to switch to the map view.

The map label for this gene is rrmA [H]

Identifier: 209695619

GI number: 209695619

Start: 2342095

End: 2342904

Strand: Reverse

Name: rrmA [H]

Synonym: VSAL_I2181

Alternate gene names: 209695619

Gene position: 2342904-2342095 (Counterclockwise)

Preceding gene: 209695621

Following gene: 209695618

Centisome position: 70.46

GC content: 38.52

Gene sequence:

>810_bases
ATGTCTTATCAATGCCCTTTATGCCAGCACGAATTACACGTTACGCATAATCAATATCGCTGTGAAAATAATCATCAATT
TGATAATGCAAAAGAAGGGTATGTGAATCTCATGCCTGCACATCATAAACGCTCGAAGAACCCGGGTGATAATAAAGAGA
TGATGCAAGCAAGACGTGCTTTTTTAGAAGCAGGACATTACCAACCTATGCAACAGCTGGTTGCTGATTTTTGTCAAACC
TACCTTACTGATGAATCATCTACCTTATTAGATATCGGTTGTGGTGAAGGTTATTACACTGCCGAAATTCAGAACCGCCT
TGTAGAAAGACGCGCTCAAGTATTTGGACTAGACATATCAAAAGTAGCGATTAAATTTGCCGCAAAACGTTATCCAAACT
GTCAATTTAGCGTGGCATCGAGCCATCGTTTGCCTTTCTCTGATCAAAGTTTAAATGGCATTGTTCGCATTTATGCGCCA
TGCAAAGCCGAAGAGTTACAACGTACGATTAAAGACGAGGGTTATTTGTTTACTGTAACCCCTGCAAGTCATCACTTATT
TGAGCTACGTGAAGAAGTTTATGGTGAAGTACGCTTACACGATGAAGCCGCTGAGGAAATTGAAGGCTTTGAATTGGTAA
AAGAAGAAAAGCTTACTTACGATATGTCATTAACGGGCATTGAAGCATTACATTTACTGGATATGACGCCTTTTTCATGG
AAAGCCACACCTGAATTTAAACATGATTTAGCAAATAAAACATCGTTCATCTGTAAAGCTGATTTCATGATAAGAGCTTA
TAAAAAATAA

Upstream 100 bases:

>100_bases
GATTCTAAGGTAATTATCGCTATAGAATATTTATCCGTGGCTCTTTTTATTCCGCCAATGAAGAAGTACACTTCGGCTAA
ACTAATTTCCAGGTGTTTCC

Downstream 100 bases:

>100_bases
ACCTACCAATCAATCTCAAAAATAAGAATACGAGATAACCCATTAATTTTAAATGGGTTATCTTTATAACGCACAATAAA
AATAGCTCGCAATTTAACAA

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSYQCPLCQHELHVTHNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQLVADFCQT
YLTDESSTLLDIGCGEGYYTAEIQNRLVERRAQVFGLDISKVAIKFAAKRYPNCQFSVASSHRLPFSDQSLNGIVRIYAP
CKAEELQRTIKDEGYLFTVTPASHHLFELREEVYGEVRLHDEAAEEIEGFELVKEEKLTYDMSLTGIEALHLLDMTPFSW
KATPEFKHDLANKTSFICKADFMIRAYKK

Sequences:

>Translated_269_residues
MSYQCPLCQHELHVTHNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQLVADFCQT
YLTDESSTLLDIGCGEGYYTAEIQNRLVERRAQVFGLDISKVAIKFAAKRYPNCQFSVASSHRLPFSDQSLNGIVRIYAP
CKAEELQRTIKDEGYLFTVTPASHHLFELREEVYGEVRLHDEAAEEIEGFELVKEEKLTYDMSLTGIEALHLLDMTPFSW
KATPEFKHDLANKTSFICKADFMIRAYKK
>Mature_268_residues
SYQCPLCQHELHVTHNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQLVADFCQTY
LTDESSTLLDIGCGEGYYTAEIQNRLVERRAQVFGLDISKVAIKFAAKRYPNCQFSVASSHRLPFSDQSLNGIVRIYAPC
KAEELQRTIKDEGYLFTVTPASHHLFELREEVYGEVRLHDEAAEEIEGFELVKEEKLTYDMSLTGIEALHLLDMTPFSWK
ATPEFKHDLANKTSFICKADFMIRAYKK

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=269, Percent_Identity=55.0185873605948, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 31086; Mature: 30954

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQCPLCQHELHVTHNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRA
CCCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHH
FLEAGHYQPMQQLVADFCQTYLTDESSTLLDIGCGEGYYTAEIQNRLVERRAQVFGLDIS
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCHH
KVAIKFAAKRYPNCQFSVASSHRLPFSDQSLNGIVRIYAPCKAEELQRTIKDEGYLFTVT
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEC
PASHHLFELREEVYGEVRLHDEAAEEIEGFELVKEEKLTYDMSLTGIEALHLLDMTPFSW
CCHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCC
KATPEFKHDLANKTSFICKADFMIRAYKK
CCCCHHHHHHHCCCEEEEEHHHHHEECCC
>Mature Secondary Structure 
SYQCPLCQHELHVTHNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRA
CCCCCCHHHHHHCCCCCEECCCCCCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHH
FLEAGHYQPMQQLVADFCQTYLTDESSTLLDIGCGEGYYTAEIQNRLVERRAQVFGLDIS
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCHH
KVAIKFAAKRYPNCQFSVASSHRLPFSDQSLNGIVRIYAPCKAEELQRTIKDEGYLFTVT
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEC
PASHHLFELREEVYGEVRLHDEAAEEIEGFELVKEEKLTYDMSLTGIEALHLLDMTPFSW
CCHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCC
KATPEFKHDLANKTSFICKADFMIRAYKK
CCCCHHHHHHHCCCEEEEEHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]