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The map label for this gene is fadH [H]

Identifier: 209695597

GI number: 209695597

Start: 2314770

End: 2316773

Strand: Reverse

Name: fadH [H]

Synonym: VSAL_I2156

Alternate gene names: 209695597

Gene position: 2316773-2314770 (Counterclockwise)

Preceding gene: 209695600

Following gene: 209695596

Centisome position: 69.67

GC content: 41.52

Gene sequence:

>2004_bases
ATGACGTACCCACACCTATTTCAACCATTAGACTTGGGTTTTACCCAATTAAAAAATCGAGTATTAATGGGCTCGATGCA
TACGGGTTTAGAAGAAAGTAACGATGGCTTTAAAAAACTATCCTCTTTTTATGCAGCACGAGCGAAAGGGGGCGTTGGTT
TGATTGTTACTGGTGGGTTTGCACCAAACTTTAGAGGTAGATTAACCCCATTTAGCGCCCAATTTAGTTCTGCTAGAGCA
GCAGAAAAACATAAAGCACTCACATCTGCTGTACATGACAACGGTGGGAAAATTGCTCTGCAATTACTTCATGCTGGGCG
TTATGCAATGCATCCCCTCGCGTTAAGTGCTTCAGATATACGCTCTCCAATTGGTATGTTTACGCCCTCTCAAATGAGTG
AGCGCCAAATTCATAAGACGATAGGTGATTTTGCAAACAGTGCCCATTACGCTAAACAAGCCAATTATGATGGTATTGAA
GTGATGGGATCTGAAGGCTATCTCATTAATCAATTTATCTGTGCTCGTACAAATATGCGTTATGACGACTGGGGCGGAAA
TTATCACAATAGAATGCGTTTCCCCTTAGAAATAATTAAAGCGATACGAGAAAAAGTAGGAGCGGATTTTATTATTATTT
TCCGTTTATCAATGCTTGATTTGGTAGAGCAAGGCAGCACATTTGAAGAGGTTGTTGAGTTAGCTCAAGCCTTAGAAAAA
GCGGGCGTGACTATTTTAAATACTGGTATTGGGTGGCATGAAACTCGAATACCAACGATATCGACACAAGTGCCAAGAGC
GGCGTTTAGTTGGGTGACTGAAAAACTAAAAAATAAAGTATCTATTCCGTTGATCACCTGCAATCGAATTAACACACCGG
AAGTAGCCGAAAATATATTGGCTTCAGGTCAAGCCGACATGGTTTCTATGGCGCGTCCATTTCTGGCTGATGCAGAGTTC
GTCAATAAAGCAGAACAAGATAAGGCCGACTTAATTAATACGTGCATTGGCTGTAATCAGGCATGTTTGGACCATGTGTT
TAAAGCAAAACGAGCCACGTGCTTAGTGAATCCCCAAGCCTGCTATGAAACGGAATTAGTGTTAGATCCCATTACCTCAA
AAAGAAATATTGCCATTATTGGGGCTGGCATGGCAGGGCTATCTTGTGCCACTTCAGCGGCTGAACGTGGTTATAACGTG
ACATTATTTGAACGAAATGACCGTATTGGTGGGCAGTTTAACTTAGCAATGGAAATCCCTGGCAAAGAAGAGTTTAAAGA
AACAATTCGTTATTTCTCGAACAAGGTAAGCCATGAAAATATTACATTAAAATTGAATCATACCGTTACGATGGAAGAGT
TGAGTAAATTTGATGATGTCGTGGTGGCGACAGGGGTTAAACCTAGAGCGCCGACTCTTGAAGGAAGTGATCACCCTAAA
GTCATCGATTACCAAACTTACATTAAAACTAAGCCACACTTGGGACAGAAAGTTGCCGTAATTGGCGCTGGTGGTATTGG
TATTGATGTCGCAACGATGATTACCGAGCCTGAAAATCAGACGCTAGACAGTTGGTTGCAAGAGTGGAATATTGATAAAA
ACATTGAATTTGAAGGCGGACTTAAACCTCAACAAACGGATAAAACAACGCGTGAAGTCTGGTTGATGCAACGTCGTAGT
GGCAGTGTTGGTAAAGGGCCAGGGAAAACGACAGGTTGGATTCACAAACGCACGTTAGAGAAACGGGGTGTGAATATGTT
GGCGGGCGTTGAATATCTGAAAGTGAATGATGAAGGTTTATATATTCGACATAATGATGAAGTGAAATTATTAGACGTTG
ACCAAGTATTAATGTGTGCAGGGCAAGTTTCGGTCAACGAATTGGTTGATACATTAATTAAAGCAAACATTACACATCAT
GTTATTGGTGGTGCAGAGCATGCCGGTGAGCTAGACGCTAAACGAGCTATTCGTCAAGGTGTTGAGTTGGCTGCAAATTT
ATAA

Upstream 100 bases:

>100_bases
AATAATGATGGATGTTGCATATTTGTAAATTCATCATTGTGTGTCCAGTAAATAATTACTATTCTGGTCTGACCACAATA
ACAATAAGCGATGGATTGCC

Downstream 100 bases:

>100_bases
TAGCGATTAGATTGACTAGAAAACTTGATAACTGTCTATTCGTACAGGTATAGTGCTGATGTTATTCACAACATCAGCAC
TTTTTTATGTCACGATTATT

Product: 2,4-dienoyl-CoA reductase [NADPH]

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MTYPHLFQPLDLGFTQLKNRVLMGSMHTGLEESNDGFKKLSSFYAARAKGGVGLIVTGGFAPNFRGRLTPFSAQFSSARA
AEKHKALTSAVHDNGGKIALQLLHAGRYAMHPLALSASDIRSPIGMFTPSQMSERQIHKTIGDFANSAHYAKQANYDGIE
VMGSEGYLINQFICARTNMRYDDWGGNYHNRMRFPLEIIKAIREKVGADFIIIFRLSMLDLVEQGSTFEEVVELAQALEK
AGVTILNTGIGWHETRIPTISTQVPRAAFSWVTEKLKNKVSIPLITCNRINTPEVAENILASGQADMVSMARPFLADAEF
VNKAEQDKADLINTCIGCNQACLDHVFKAKRATCLVNPQACYETELVLDPITSKRNIAIIGAGMAGLSCATSAAERGYNV
TLFERNDRIGGQFNLAMEIPGKEEFKETIRYFSNKVSHENITLKLNHTVTMEELSKFDDVVVATGVKPRAPTLEGSDHPK
VIDYQTYIKTKPHLGQKVAVIGAGGIGIDVATMITEPENQTLDSWLQEWNIDKNIEFEGGLKPQQTDKTTREVWLMQRRS
GSVGKGPGKTTGWIHKRTLEKRGVNMLAGVEYLKVNDEGLYIRHNDEVKLLDVDQVLMCAGQVSVNELVDTLIKANITHH
VIGGAEHAGELDAKRAIRQGVELAANL

Sequences:

>Translated_667_residues
MTYPHLFQPLDLGFTQLKNRVLMGSMHTGLEESNDGFKKLSSFYAARAKGGVGLIVTGGFAPNFRGRLTPFSAQFSSARA
AEKHKALTSAVHDNGGKIALQLLHAGRYAMHPLALSASDIRSPIGMFTPSQMSERQIHKTIGDFANSAHYAKQANYDGIE
VMGSEGYLINQFICARTNMRYDDWGGNYHNRMRFPLEIIKAIREKVGADFIIIFRLSMLDLVEQGSTFEEVVELAQALEK
AGVTILNTGIGWHETRIPTISTQVPRAAFSWVTEKLKNKVSIPLITCNRINTPEVAENILASGQADMVSMARPFLADAEF
VNKAEQDKADLINTCIGCNQACLDHVFKAKRATCLVNPQACYETELVLDPITSKRNIAIIGAGMAGLSCATSAAERGYNV
TLFERNDRIGGQFNLAMEIPGKEEFKETIRYFSNKVSHENITLKLNHTVTMEELSKFDDVVVATGVKPRAPTLEGSDHPK
VIDYQTYIKTKPHLGQKVAVIGAGGIGIDVATMITEPENQTLDSWLQEWNIDKNIEFEGGLKPQQTDKTTREVWLMQRRS
GSVGKGPGKTTGWIHKRTLEKRGVNMLAGVEYLKVNDEGLYIRHNDEVKLLDVDQVLMCAGQVSVNELVDTLIKANITHH
VIGGAEHAGELDAKRAIRQGVELAANL
>Mature_666_residues
TYPHLFQPLDLGFTQLKNRVLMGSMHTGLEESNDGFKKLSSFYAARAKGGVGLIVTGGFAPNFRGRLTPFSAQFSSARAA
EKHKALTSAVHDNGGKIALQLLHAGRYAMHPLALSASDIRSPIGMFTPSQMSERQIHKTIGDFANSAHYAKQANYDGIEV
MGSEGYLINQFICARTNMRYDDWGGNYHNRMRFPLEIIKAIREKVGADFIIIFRLSMLDLVEQGSTFEEVVELAQALEKA
GVTILNTGIGWHETRIPTISTQVPRAAFSWVTEKLKNKVSIPLITCNRINTPEVAENILASGQADMVSMARPFLADAEFV
NKAEQDKADLINTCIGCNQACLDHVFKAKRATCLVNPQACYETELVLDPITSKRNIAIIGAGMAGLSCATSAAERGYNVT
LFERNDRIGGQFNLAMEIPGKEEFKETIRYFSNKVSHENITLKLNHTVTMEELSKFDDVVVATGVKPRAPTLEGSDHPKV
IDYQTYIKTKPHLGQKVAVIGAGGIGIDVATMITEPENQTLDSWLQEWNIDKNIEFEGGLKPQQTDKTTREVWLMQRRSG
SVGKGPGKTTGWIHKRTLEKRGVNMLAGVEYLKVNDEGLYIRHNDEVKLLDVDQVLMCAGQVSVNELVDTLIKANITHHV
IGGAEHAGELDAKRAIRQGVELAANL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=669, Percent_Identity=55.1569506726457, Blast_Score=786, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=357, Percent_Identity=26.3305322128852, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=264, Percent_Identity=28.030303030303, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=249, Percent_Identity=29.3172690763052, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=232, Percent_Identity=27.1551724137931, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=277, Percent_Identity=26.7148014440433, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=27.6595744680851, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=242, Percent_Identity=26.4462809917355, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73558; Mature: 73427

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPHLFQPLDLGFTQLKNRVLMGSMHTGLEESNDGFKKLSSFYAARAKGGVGLIVTGGF
CCCCCCCCCHHCCHHHHHCCEEECHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
APNFRGRLTPFSAQFSSARAAEKHKALTSAVHDNGGKIALQLLHAGRYAMHPLALSASDI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCEECHHHH
RSPIGMFTPSQMSERQIHKTIGDFANSAHYAKQANYDGIEVMGSEGYLINQFICARTNMR
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCC
YDDWGGNYHNRMRFPLEIIKAIREKVGADFIIIFRLSMLDLVEQGSTFEEVVELAQALEK
CCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGVTILNTGIGWHETRIPTISTQVPRAAFSWVTEKLKNKVSIPLITCNRINTPEVAENIL
CCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADAEFVNKAEQDKADLINTCIGCNQACLDHVFKAKRATCLVNPQA
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCHH
CYETELVLDPITSKRNIAIIGAGMAGLSCATSAAERGYNVTLFERNDRIGGQFNLAMEIP
HCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECC
GKEEFKETIRYFSNKVSHENITLKLNHTVTMEELSKFDDVVVATGVKPRAPTLEGSDHPK
CHHHHHHHHHHHHHCCCCCEEEEEEECEEEHHHHHHHCCEEEECCCCCCCCCCCCCCCCC
VIDYQTYIKTKPHLGQKVAVIGAGGIGIDVATMITEPENQTLDSWLQEWNIDKNIEFEGG
EEEEHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCC
LKPQQTDKTTREVWLMQRRSGSVGKGPGKTTGWIHKRTLEKRGVNMLAGVEYLKVNDEGL
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEECCCEE
YIRHNDEVKLLDVDQVLMCAGQVSVNELVDTLIKANITHHVIGGAEHAGELDAKRAIRQG
EEEECCCEEEEEHHHHHHHCCCCCHHHHHHHHHHCCCHHEECCCCHHCCHHHHHHHHHHH
VELAANL
HHHHCCC
>Mature Secondary Structure 
TYPHLFQPLDLGFTQLKNRVLMGSMHTGLEESNDGFKKLSSFYAARAKGGVGLIVTGGF
CCCCCCCCHHCCHHHHHCCEEECHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
APNFRGRLTPFSAQFSSARAAEKHKALTSAVHDNGGKIALQLLHAGRYAMHPLALSASDI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCEECHHHH
RSPIGMFTPSQMSERQIHKTIGDFANSAHYAKQANYDGIEVMGSEGYLINQFICARTNMR
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCC
YDDWGGNYHNRMRFPLEIIKAIREKVGADFIIIFRLSMLDLVEQGSTFEEVVELAQALEK
CCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGVTILNTGIGWHETRIPTISTQVPRAAFSWVTEKLKNKVSIPLITCNRINTPEVAENIL
CCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADAEFVNKAEQDKADLINTCIGCNQACLDHVFKAKRATCLVNPQA
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCHH
CYETELVLDPITSKRNIAIIGAGMAGLSCATSAAERGYNVTLFERNDRIGGQFNLAMEIP
HCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECC
GKEEFKETIRYFSNKVSHENITLKLNHTVTMEELSKFDDVVVATGVKPRAPTLEGSDHPK
CHHHHHHHHHHHHHCCCCCEEEEEEECEEEHHHHHHHCCEEEECCCCCCCCCCCCCCCCC
VIDYQTYIKTKPHLGQKVAVIGAGGIGIDVATMITEPENQTLDSWLQEWNIDKNIEFEGG
EEEEHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCC
LKPQQTDKTTREVWLMQRRSGSVGKGPGKTTGWIHKRTLEKRGVNMLAGVEYLKVNDEGL
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEECCCEE
YIRHNDEVKLLDVDQVLMCAGQVSVNELVDTLIKANITHHVIGGAEHAGELDAKRAIRQG
EEEECCCEEEEEHHHHHHHCCCCCHHHHHHHHHHCCCHHEECCCCHHCCHHHHHHHHHHH
VELAANL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]