BacMap

Definition	Aliivibrio salmonicida LFI1238 chromosome 1, complete genome.
Accession	NC_011312
Length	3,325,165

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The map label for this gene is fabG [H]

Identifier: 209695534

GI number: 209695534

Start: 2240661

End: 2241386

Strand: Reverse

Name: fabG [H]

Synonym: VSAL_I2090

Alternate gene names: 209695534

Gene position: 2241386-2240661 (Counterclockwise)

Preceding gene: 209695535

Following gene: 209695533

Centisome position: 67.41

GC content: 44.35

Gene sequence:

>726_bases
ATGATAAGACAAGTATTAGTGACCGGAGCAAGTAAAGGTATTGGTCGCGCAATTTCAGAGCAGTTAGCAAAAGATGGTTT
TCATGTGGTGGTTCACTATATGAGTGACAAAGCAGGCGCAGAGAAAACAATCGAGACGATTGAAGCGAATGGCGGTTCAG
GCCGTTTAATTCAGTTTGATATTAGTGATCGTGTTCAGTGTCGACTCATGCTTGAACACGATATCGAAGTGAATGGTGCG
TATTACGGTGTCGTAAGTAATGCGGGCATTACTCGCGATACGGCTTTTCCTGCAATGACAGAGGGAGAGTGGGACAGCGT
TATTCACACTAACTTAGACAGCTTTTATAATGTACTTCACCCTTGTGTTATGCCAATGGTGAGAACACGTAAAGGCGGTC
GTATCGTTACGTTAGCGTCAGTCTCAGGCATTGTTGGTAATCGTGGGCAAACCAATTACAGTGCGGCTAAAGCGGGTGTG
ATTGGTGCAACCAAATCATTAGCACTTGAGTTAGCAAAACGAAAAATCACGGTAAATTGTGTGGCTCCAGGGCTTATCGA
TACAGGAATGGTCGATGAACATGTAAAAGAACACGCCTTACCACAAGTTCCATTACGTCGTATGGGTGAACCTGAAGAGG
TTGCCGGTCTAGTGAGTTATTTGATGTCGGATGTCGCGGGTTATGTTACTCGCCAAGTCATTTCAATTAATGGTGGTTTA
GTATGA

Upstream 100 bases:

>100_bases
ATAACGGTCAGCAATTGGCATCAAGCCAATTAAATGTATTTGTACCGACAGAAGATAAATTAGAAGAGCTCTTAGCGCCA
AAGCAGTAGTAGAGGAAATC

Downstream 100 bases:

>100_bases
GTCGTCGTGTTGTTGTAACCGGAATGTCAGGGGTAACTGCACTTGGCAGTGATTGGAATACGGTAGGCGAAAATCTTCGT
AAGTGTGAAAATGCGACCCA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIRQVLVTGASKGIGRAISEQLAKDGFHVVVHYMSDKAGAEKTIETIEANGGSGRLIQFDISDRVQCRLMLEHDIEVNGA
YYGVVSNAGITRDTAFPAMTEGEWDSVIHTNLDSFYNVLHPCVMPMVRTRKGGRIVTLASVSGIVGNRGQTNYSAAKAGV
IGATKSLALELAKRKITVNCVAPGLIDTGMVDEHVKEHALPQVPLRRMGEPEEVAGLVSYLMSDVAGYVTRQVISINGGL
V

Sequences:

>Translated_241_residues
MIRQVLVTGASKGIGRAISEQLAKDGFHVVVHYMSDKAGAEKTIETIEANGGSGRLIQFDISDRVQCRLMLEHDIEVNGA
YYGVVSNAGITRDTAFPAMTEGEWDSVIHTNLDSFYNVLHPCVMPMVRTRKGGRIVTLASVSGIVGNRGQTNYSAAKAGV
IGATKSLALELAKRKITVNCVAPGLIDTGMVDEHVKEHALPQVPLRRMGEPEEVAGLVSYLMSDVAGYVTRQVISINGGL
V
>Mature_241_residues
MIRQVLVTGASKGIGRAISEQLAKDGFHVVVHYMSDKAGAEKTIETIEANGGSGRLIQFDISDRVQCRLMLEHDIEVNGA
YYGVVSNAGITRDTAFPAMTEGEWDSVIHTNLDSFYNVLHPCVMPMVRTRKGGRIVTLASVSGIVGNRGQTNYSAAKAGV
IGATKSLALELAKRKITVNCVAPGLIDTGMVDEHVKEHALPQVPLRRMGEPEEVAGLVSYLMSDVAGYVTRQVISINGGL
V

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=37.7510040160643, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.2314049586777, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=33.1967213114754, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4504505, Length=227, Percent_Identity=33.920704845815, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.1204819277108, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI66933014, Length=149, Percent_Identity=33.5570469798658, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI59889578, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=211, Percent_Identity=29.3838862559242, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=42.8571428571429, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=34.4262295081967, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.6, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=34.412955465587, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=27.8688524590164, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=27.8008298755187, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=25.8196721311475, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=28.1512605042017, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.9352226720648, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=29.3436293436293, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=29.0983606557377, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=27.5590551181102, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=235, Percent_Identity=28.0851063829787, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=37.603305785124, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=38.4297520661157, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=33.59375, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17568967, Length=230, Percent_Identity=33.0434782608696, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=31.0483870967742, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=30.9803921568627, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=31.7708333333333, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=26.8, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=256, Percent_Identity=26.953125, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=26.4227642276423, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=26.6129032258064, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=206, Percent_Identity=26.2135922330097, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=26.2745098039216, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=33.1983805668016, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=27.9569892473118, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=210, Percent_Identity=24.2857142857143, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=35.7723577235772, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=33.2, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=34.5528455284553, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=32.2314049586777, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.8548387096774, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=30.7377049180328, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859837, Length=227, Percent_Identity=28.6343612334802, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=29.6442687747036, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=37.0689655172414, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25852; Mature: 25852

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQVLVTGASKGIGRAISEQLAKDGFHVVVHYMSDKAGAEKTIETIEANGGSGRLIQFD
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEE
ISDRVQCRLMLEHDIEVNGAYYGVVSNAGITRDTAFPAMTEGEWDSVIHTNLDSFYNVLH
CCCCEEEEEEEECCEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHH
PCVMPMVRTRKGGRIVTLASVSGIVGNRGQTNYSAAKAGVIGATKSLALELAKRKITVNC
HHHHHHHHCCCCCEEEEEEEECCHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEE
VAPGLIDTGMVDEHVKEHALPQVPLRRMGEPEEVAGLVSYLMSDVAGYVTRQVISINGGL
ECCCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
V
C
>Mature Secondary Structure
MIRQVLVTGASKGIGRAISEQLAKDGFHVVVHYMSDKAGAEKTIETIEANGGSGRLIQFD
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEE
ISDRVQCRLMLEHDIEVNGAYYGVVSNAGITRDTAFPAMTEGEWDSVIHTNLDSFYNVLH
CCCCEEEEEEEECCEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHH
PCVMPMVRTRKGGRIVTLASVSGIVGNRGQTNYSAAKAGVIGATKSLALELAKRKITVNC
HHHHHHHHCCCCCEEEEEEEECCHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEE
VAPGLIDTGMVDEHVKEHALPQVPLRRMGEPEEVAGLVSYLMSDVAGYVTRQVISINGGL
ECCCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]