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The map label for this gene is queC

Identifier: 209695424

GI number: 209695424

Start: 2108585

End: 2109268

Strand: Reverse

Name: queC

Synonym: VSAL_I1965

Alternate gene names: 209695424

Gene position: 2109268-2108585 (Counterclockwise)

Preceding gene: 209695425

Following gene: 209695422

Centisome position: 63.43

GC content: 37.13

Gene sequence:

>684_bases
ATGTCTACAGCTATTGTTGTTTTTAGTGGCGGTCAAGATTCGACCACTTGTTTAATTCAAGCACTTACCCATTATGATCA
TGTTCATTGTATTACTTTTGATTATGGCCAACGTCATAATCAAGAAATTGAAGTAGCTAAATCTGTCGCTTTAGACTTAG
GGGCAACCTCTCACAAAGTCATGGATGTGGGTTTATTAAATGAATTGGCCGTCAGTTCGTTAACTCGCGATAACATACCG
GTTTCTCATGAACTGCAAGAGAATGGTTTACCGAATTCATTTGTTCCTGGTCGTAATATTTTATTTTTAACTCTTGCTGG
TATTTATGCATACCAATTAGGTGCAGAAAGCGTTATCACGGGCGTATGTGAAACTGACTTTTCTGGTTACCCTGATTGTC
GAGATGAATTTGTAAAATCGATTAATCAATCTCTTGTATTAGGAATGGATCGTAAACTAAAAATCGATACTCCTTTAATG
TGGCTAAATAAAGCGGAAACGTGGGCATTAGCCGATAAGTACGGCAAGTTAGATTATGTTCGTAATCAAACATTAACGTG
CTATAACGGCGTTATTGGTGATGGCTGTGGTGATTGCCCATCATGTGACTTACGCAAAAATGGTTTAGACGACTATTTAG
CAAATAAAGAATCAGTAATGGCTGACTTAGAGTCAAAAATTTAA

Upstream 100 bases:

>100_bases
CGAGTAAACCCCATAATCAAAGCCATCATTAACGTGATGGCTTTTTTATCTATTCTTCCTTACTATGCTCACTAATTACA
AAACTTGGAGTTAATGACCT

Downstream 100 bases:

>100_bases
TACTGATGTTTGCTTTATTCATGCATAAAAAAACCGCAAAGTAATCGTATTACTTTGCGGTTTTTTATATCAATCACATC
TATGTACTTAGTGTGATATT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSTAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKVMDVGLLNELAVSSLTRDNIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLM
WLNKAETWALADKYGKLDYVRNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI

Sequences:

>Translated_227_residues
MSTAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKVMDVGLLNELAVSSLTRDNIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLM
WLNKAETWALADKYGKLDYVRNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI
>Mature_226_residues
STAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKVMDVGLLNELAVSSLTRDNIPV
SHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLMW
LNKAETWALADKYGKLDYVRNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=70.4845814977974, Blast_Score=350, Evalue=5e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ALISL (B6EH68)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263353.1
- GeneID:   6987477
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1965
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   PRK11106
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24950; Mature: 24818

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKV
CCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHH
MDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVIT
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHH
GVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLMWLNKAETWALADKYGKLDYV
HHHCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEECCCEEEECCCCHHHHHHHHCCHHHH
RNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
STAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKV
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHH
MDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVIT
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHH
GVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLMWLNKAETWALADKYGKLDYV
HHHCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEECCCEEEECCCCHHHHHHHHCCHHHH
RNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA