Click here to switch to the map view.

The map label for this gene is phnW [H]

Identifier: 209695290

GI number: 209695290

Start: 1939747

End: 1940967

Strand: Reverse

Name: phnW [H]

Synonym: VSAL_I1817

Alternate gene names: 209695290

Gene position: 1940967-1939747 (Counterclockwise)

Preceding gene: 209695293

Following gene: 209695289

Centisome position: 58.37

GC content: 35.05

Gene sequence:

>1221_bases
TTGTCGTTATCTGGAGATATTGCATTGAATAAATATTTATTATTAACCCCAGGTCCGGTCAACGTAGCTAACAATGTTCG
AATGGCGATTGCTAAAGAAGACATTTGTCATCGCGAAGTTGATTTTGATTTACTGTTGGCAGGTATTGAACAAAAATTGC
TTAACGTTTTTGAAATAAAAGCCGTTGATGATTATAGAGCGGTTGTTATTACCGGCTCAGGAACCGCAGCAAATGAAGCC
ATGCTTTCTTCTGTTGTTGGTGACAAAAAAATTCTTGTTCTTTCTAACGGAGAGTTTGGGGATCGTTTACATGAAATATC
TAAAATCCACAATCAGAACACTTCTGTACTTGAATTTCCATGGGGACAGAGCTTAGATATTAATATTATTTCTGATTATT
TAGAGCACAATTCTATTGATGTAATAGCAATGGTTCATCATGAAACAAGCTCAGGTATTCTCAATTCTTTAGAGCAAATT
GGCACACTAGCAAAAATACATAATGCCAAATTCATCGTCGATTGTGTCAGCAGCGCTGGTGCTGAAGCCATCGATGTGAA
ACGAAATAATATCGATTTCTTCTCAAGTTCAAGCTCTAAAGCCTTAGGCTCATACCCTGGTTTATCATTCGTTATAGGTA
AAACCACTGAATTCGAAAAGTTAAAAAATTATCCGATAAAAACGGCATACCTGAATTTATATAAATTTTATACTTTCCTT
AAAACCGTATCACAAACACCTAACACACCTGCTGTACCATTATTTTTTGCACTTGATCAAGCATTAAGCAACATACTCGA
ACAAGGGGTAGCAAATCGCTACGCAGACCTACGAAGTAAAGCGAATTTTTTACGCAGCGGTATGCAAAAACTAGGATTCA
ATTTTTTACTCCATGAACGTGATATGTGCTCAATATTAACCTCAGTTTATGTACCTGCGGATATTGACGTAGATGTGCTT
CGCCAAAAACTTCGAGATAAATCCATTATTATTTATGAGGGTAAAGGATGCTTTAAACATAAAGTATTTCAAGTAGGCAA
TATTGGAGAGATTTCTTTTGAAGATATTCAATTCTTCTTAGATATACAAAAAGAAATCTTACAAAGCAGCAATATACTCG
AAAGTCATAAGCTAATTTCATTGCCAAAAATACGTCCTTTAATCAATAAAACGAAATCCATATTAACCCCTTCTCCATTA
GTTGCTGTGAGCATAGTATAA

Upstream 100 bases:

>100_bases
TTAATTTGTTGTTTATCTAACGGAAGAAAAATGCATCACCTTTTGCATCTTCAATAAGCGCTAAACATAATTAACATTAC
CGATAATATCAACATAACTG

Downstream 100 bases:

>100_bases
ATGAATATTTCAAATGAAAAATTAACCAAATTATGGGCAACTAAAAATAAGGACGACGAATGGTGGTCATCTTTTGTGAC
TTCACCATTAGCTATTTTTG

Product: aminotransferase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSLSGDIALNKYLLLTPGPVNVANNVRMAIAKEDICHREVDFDLLLAGIEQKLLNVFEIKAVDDYRAVVITGSGTAANEA
MLSSVVGDKKILVLSNGEFGDRLHEISKIHNQNTSVLEFPWGQSLDINIISDYLEHNSIDVIAMVHHETSSGILNSLEQI
GTLAKIHNAKFIVDCVSSAGAEAIDVKRNNIDFFSSSSSKALGSYPGLSFVIGKTTEFEKLKNYPIKTAYLNLYKFYTFL
KTVSQTPNTPAVPLFFALDQALSNILEQGVANRYADLRSKANFLRSGMQKLGFNFLLHERDMCSILTSVYVPADIDVDVL
RQKLRDKSIIIYEGKGCFKHKVFQVGNIGEISFEDIQFFLDIQKEILQSSNILESHKLISLPKIRPLINKTKSILTPSPL
VAVSIV

Sequences:

>Translated_406_residues
MSLSGDIALNKYLLLTPGPVNVANNVRMAIAKEDICHREVDFDLLLAGIEQKLLNVFEIKAVDDYRAVVITGSGTAANEA
MLSSVVGDKKILVLSNGEFGDRLHEISKIHNQNTSVLEFPWGQSLDINIISDYLEHNSIDVIAMVHHETSSGILNSLEQI
GTLAKIHNAKFIVDCVSSAGAEAIDVKRNNIDFFSSSSSKALGSYPGLSFVIGKTTEFEKLKNYPIKTAYLNLYKFYTFL
KTVSQTPNTPAVPLFFALDQALSNILEQGVANRYADLRSKANFLRSGMQKLGFNFLLHERDMCSILTSVYVPADIDVDVL
RQKLRDKSIIIYEGKGCFKHKVFQVGNIGEISFEDIQFFLDIQKEILQSSNILESHKLISLPKIRPLINKTKSILTPSPL
VAVSIV
>Mature_405_residues
SLSGDIALNKYLLLTPGPVNVANNVRMAIAKEDICHREVDFDLLLAGIEQKLLNVFEIKAVDDYRAVVITGSGTAANEAM
LSSVVGDKKILVLSNGEFGDRLHEISKIHNQNTSVLEFPWGQSLDINIISDYLEHNSIDVIAMVHHETSSGILNSLEQIG
TLAKIHNAKFIVDCVSSAGAEAIDVKRNNIDFFSSSSSKALGSYPGLSFVIGKTTEFEKLKNYPIKTAYLNLYKFYTFLK
TVSQTPNTPAVPLFFALDQALSNILEQGVANRYADLRSKANFLRSGMQKLGFNFLLHERDMCSILTSVYVPADIDVDVLR
QKLRDKSIIIYEGKGCFKHKVFQVGNIGEISFEDIQFFLDIQKEILQSSNILESHKLISLPKIRPLINKTKSILTPSPLV
AVSIV

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=355, Percent_Identity=27.3239436619718, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17536281, Length=351, Percent_Identity=23.3618233618234, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321079, Length=345, Percent_Identity=25.2173913043478, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17530823, Length=370, Percent_Identity=23.2432432432432, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 45014; Mature: 44883

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSGDIALNKYLLLTPGPVNVANNVRMAIAKEDICHREVDFDLLLAGIEQKLLNVFEIK
CCCCCCEEECEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
AVDDYRAVVITGSGTAANEAMLSSVVGDKKILVLSNGEFGDRLHEISKIHNQNTSVLEFP
EECCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECC
WGQSLDINIISDYLEHNSIDVIAMVHHETSSGILNSLEQIGTLAKIHNAKFIVDCVSSAG
CCCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCC
AEAIDVKRNNIDFFSSSSSKALGSYPGLSFVIGKTTEFEKLKNYPIKTAYLNLYKFYTFL
CCEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHH
KTVSQTPNTPAVPLFFALDQALSNILEQGVANRYADLRSKANFLRSGMQKLGFNFLLHER
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DMCSILTSVYVPADIDVDVLRQKLRDKSIIIYEGKGCFKHKVFQVGNIGEISFEDIQFFL
HHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHEECCCCCCCCHHHHHHHH
DIQKEILQSSNILESHKLISLPKIRPLINKTKSILTPSPLVAVSIV
HHHHHHHHHCCCHHHCCEECCCCHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
SLSGDIALNKYLLLTPGPVNVANNVRMAIAKEDICHREVDFDLLLAGIEQKLLNVFEIK
CCCCCEEECEEEEEECCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
AVDDYRAVVITGSGTAANEAMLSSVVGDKKILVLSNGEFGDRLHEISKIHNQNTSVLEFP
EECCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECC
WGQSLDINIISDYLEHNSIDVIAMVHHETSSGILNSLEQIGTLAKIHNAKFIVDCVSSAG
CCCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCC
AEAIDVKRNNIDFFSSSSSKALGSYPGLSFVIGKTTEFEKLKNYPIKTAYLNLYKFYTFL
CCEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHH
KTVSQTPNTPAVPLFFALDQALSNILEQGVANRYADLRSKANFLRSGMQKLGFNFLLHER
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DMCSILTSVYVPADIDVDVLRQKLRDKSIIIYEGKGCFKHKVFQVGNIGEISFEDIQFFL
HHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHEECCCCCCCCHHHHHHHH
DIQKEILQSSNILESHKLISLPKIRPLINKTKSILTPSPLVAVSIV
HHHHHHHHHCCCHHHCCEECCCCHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA