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The map label for this gene is glpT [H]

Identifier: 209695202

GI number: 209695202

Start: 1823160

End: 1824611

Strand: Reverse

Name: glpT [H]

Synonym: VSAL_I1713

Alternate gene names: 209695202

Gene position: 1824611-1823160 (Counterclockwise)

Preceding gene: 209695205

Following gene: 209695201

Centisome position: 54.87

GC content: 42.7

Gene sequence:

>1452_bases
ATGCGCATCACTTTCGAACGAAATGTTTTATTTGATTGTTCGAGCTTTATGTTGTTCACCATCGCAAATATAATAACGGA
GTTAACTATGTTTGGTATATTTAAACCCCAAGCGCATATAGCACGCCTCGCTTCTAATCAGATAGATGGCACCTATACTC
GCTTACGTTGGCAATTGTTCCTCAGTATTTTCGTCGGTTATGCCGGTTACTACCTAGTTCGTAAGAACTTCAGTTTAGCA
ATGCCTTATTTGATTGACCAAGGTTTTAGCCGTGGGGATCTTGGTGTTGCTTTAGCGGCGGTATCTATTGCTTATGGGCT
GTCAAAGTTCTTAATGGGCAGTGTGTCTGACCGTTCTAATCCTCGATATTTTCTCAGTGCGGGCTTATTGATGTCTGCCG
CTGTTATGTTCTGCTTTGGTTTTATGCCTTGGGCGACAAACAGTATTACGGCAATGTTCATTTTATTATTCTTGAACGGT
TGGTTTCAAGGCATGGGGTGGCCTGCATGCGGTCGAACGATGGTGCATTGGTGGTCACGTAAAGAACGTGGTGAACTGGT
TTCGGTTTGGAACGTTGCACACAATGTGGGGGGCGGGTTAATTGGTCCTCTTTTCTTATTGGGCCTTTGGGCATTTAACG
ACGATTGGCGCTCAGCATTTTATGTACCAGCCATTTTTGCCACGTTAGTTGCTGTTTTCATTTGGGCTACATTGCGTGAT
ACGCCTCAATCTTGTGGTTTACCAGCGATTGAAGAATACAAAAATGATTATCCAGATGATTACGATAAGTCTCATGAAAA
TGAGATGACAGCAAAAGAGATTTTCTTTAAATACGTGTTCAATAATAAGCTGCTTTGGTCTATCGCGATTGCAAACGCGT
TTGTTTATCTGATTCGCTACGGTGTGCTTGATTGGGCTCCTGTGTATTTAAAAGAAGCGAAAGGTTTCACCGTTGATAAA
TCATCTTGGGCGTATTTCTTATATGAGTGGGCTGGTATCCCAGGTACATTGTTATGTGGTTGGATTTCAGACAAAGTATT
TAAAGGACGTCGTGCACCTGCTGGCATCTTATTTATGGTGCTTGTAACTGCTGCGGTATTAGTTTATTGGTTTAATCCTG
CGGGAAATCCAACGATTGATATGATTGCATTAGTGGCTATTGGGTTCTTAATTTATGGCCCTGTGATGCTTATTGGCCTT
TATGCACTTGAGCTTGTTCCTAAAAAAGCAGCAGGTACTGCGGCTGGCCTTACTGGGTTGTTTGGTTATCTTGGTGGTGC
CGTTACCGCAAACATTGTATTAGGTTATACCGTAGACCACTTTGGTTGGGATGGTGGCTTTATGATTCTGGTTGCTTCTT
GTGTGTTGTCTATCATGTGCTTGTGTTACGCCTTCTTAGGAGAGCGTGCACATCATAAAGCGAAAGACAAAGAGCAAGCG
ACGATATCGTAA

Upstream 100 bases:

>100_bases
TTTTATTTGTTAGGTGTAGTTCCCCGCACGCTTACATTAAATAAACTAATTAGTCAATTTGTAATATTTGTCACAGAAAT
AGATTCGTTTGAACATCATA

Downstream 100 bases:

>100_bases
TCAAAACATCATAAATATGAAGTTATATGAGTTTAGTTTTTGTATACACAAACTGTGATTATCAGTAACTAAATTATAAT
GGCTTTCCCCCTACCGTTGT

Product: sn-glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRITFERNVLFDCSSFMLFTIANIITELTMFGIFKPQAHIARLASNQIDGTYTRLRWQLFLSIFVGYAGYYLVRKNFSLA
MPYLIDQGFSRGDLGVALAAVSIAYGLSKFLMGSVSDRSNPRYFLSAGLLMSAAVMFCFGFMPWATNSITAMFILLFLNG
WFQGMGWPACGRTMVHWWSRKERGELVSVWNVAHNVGGGLIGPLFLLGLWAFNDDWRSAFYVPAIFATLVAVFIWATLRD
TPQSCGLPAIEEYKNDYPDDYDKSHENEMTAKEIFFKYVFNNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKGFTVDK
SSWAYFLYEWAGIPGTLLCGWISDKVFKGRRAPAGILFMVLVTAAVLVYWFNPAGNPTIDMIALVAIGFLIYGPVMLIGL
YALELVPKKAAGTAAGLTGLFGYLGGAVTANIVLGYTVDHFGWDGGFMILVASCVLSIMCLCYAFLGERAHHKAKDKEQA
TIS

Sequences:

>Translated_483_residues
MRITFERNVLFDCSSFMLFTIANIITELTMFGIFKPQAHIARLASNQIDGTYTRLRWQLFLSIFVGYAGYYLVRKNFSLA
MPYLIDQGFSRGDLGVALAAVSIAYGLSKFLMGSVSDRSNPRYFLSAGLLMSAAVMFCFGFMPWATNSITAMFILLFLNG
WFQGMGWPACGRTMVHWWSRKERGELVSVWNVAHNVGGGLIGPLFLLGLWAFNDDWRSAFYVPAIFATLVAVFIWATLRD
TPQSCGLPAIEEYKNDYPDDYDKSHENEMTAKEIFFKYVFNNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKGFTVDK
SSWAYFLYEWAGIPGTLLCGWISDKVFKGRRAPAGILFMVLVTAAVLVYWFNPAGNPTIDMIALVAIGFLIYGPVMLIGL
YALELVPKKAAGTAAGLTGLFGYLGGAVTANIVLGYTVDHFGWDGGFMILVASCVLSIMCLCYAFLGERAHHKAKDKEQA
TIS
>Mature_483_residues
MRITFERNVLFDCSSFMLFTIANIITELTMFGIFKPQAHIARLASNQIDGTYTRLRWQLFLSIFVGYAGYYLVRKNFSLA
MPYLIDQGFSRGDLGVALAAVSIAYGLSKFLMGSVSDRSNPRYFLSAGLLMSAAVMFCFGFMPWATNSITAMFILLFLNG
WFQGMGWPACGRTMVHWWSRKERGELVSVWNVAHNVGGGLIGPLFLLGLWAFNDDWRSAFYVPAIFATLVAVFIWATLRD
TPQSCGLPAIEEYKNDYPDDYDKSHENEMTAKEIFFKYVFNNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKGFTVDK
SSWAYFLYEWAGIPGTLLCGWISDKVFKGRRAPAGILFMVLVTAAVLVYWFNPAGNPTIDMIALVAIGFLIYGPVMLIGL
YALELVPKKAAGTAAGLTGLFGYLGGAVTANIVLGYTVDHFGWDGGFMILVASCVLSIMCLCYAFLGERAHHKAKDKEQA
TIS

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=418, Percent_Identity=27.2727272727273, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4503847, Length=418, Percent_Identity=27.2727272727273, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI256219483, Length=418, Percent_Identity=27.2727272727273, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI256219543, Length=440, Percent_Identity=25.9090909090909, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI256219564, Length=349, Percent_Identity=24.9283667621776, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38093649, Length=465, Percent_Identity=25.5913978494624, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI223717983, Length=465, Percent_Identity=25.5913978494624, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI46361976, Length=383, Percent_Identity=26.6318537859008, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788573, Length=450, Percent_Identity=69.1111111111111, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI87082310, Length=429, Percent_Identity=36.3636363636364, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI2367259, Length=441, Percent_Identity=33.5600907029478, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1789515, Length=439, Percent_Identity=25.5125284738041, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=24.4292237442922, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87082320, Length=443, Percent_Identity=24.3792325056433, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367379, Length=310, Percent_Identity=22.9032258064516, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133930953, Length=481, Percent_Identity=22.6611226611227, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI133901854, Length=453, Percent_Identity=23.3995584988962, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI133901856, Length=453, Percent_Identity=23.3995584988962, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17542316, Length=476, Percent_Identity=23.3193277310924, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564202, Length=459, Percent_Identity=23.5294117647059, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564204, Length=391, Percent_Identity=24.0409207161125, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24656866, Length=489, Percent_Identity=22.2903885480573, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45550478, Length=489, Percent_Identity=22.2903885480573, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24656861, Length=489, Percent_Identity=22.2903885480573, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53868; Mature: 53868

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00018 EF_HAND_1 ; PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITFERNVLFDCSSFMLFTIANIITELTMFGIFKPQAHIARLASNQIDGTYTRLRWQLF
CEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHH
LSIFVGYAGYYLVRKNFSLAMPYLIDQGFSRGDLGVALAAVSIAYGLSKFLMGSVSDRSN
HHHHHHHHHHHHEECCCCHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRYFLSAGLLMSAAVMFCFGFMPWATNSITAMFILLFLNGWFQGMGWPACGRTMVHWWSR
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
KERGELVSVWNVAHNVGGGLIGPLFLLGLWAFNDDWRSAFYVPAIFATLVAVFIWATLRD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPQSCGLPAIEEYKNDYPDDYDKSHENEMTAKEIFFKYVFNNKLLWSIAIANAFVYLIRY
CHHHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GVLDWAPVYLKEAKGFTVDKSSWAYFLYEWAGIPGTLLCGWISDKVFKGRRAPAGILFMV
HHHCCCHHHHHHCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LVTAAVLVYWFNPAGNPTIDMIALVAIGFLIYGPVMLIGLYALELVPKKAAGTAAGLTGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FGYLGGAVTANIVLGYTVDHFGWDGGFMILVASCVLSIMCLCYAFLGERAHHKAKDKEQA
HHHHHHHHHHHEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TIS
CCC
>Mature Secondary Structure
MRITFERNVLFDCSSFMLFTIANIITELTMFGIFKPQAHIARLASNQIDGTYTRLRWQLF
CEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHH
LSIFVGYAGYYLVRKNFSLAMPYLIDQGFSRGDLGVALAAVSIAYGLSKFLMGSVSDRSN
HHHHHHHHHHHHEECCCCHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRYFLSAGLLMSAAVMFCFGFMPWATNSITAMFILLFLNGWFQGMGWPACGRTMVHWWSR
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
KERGELVSVWNVAHNVGGGLIGPLFLLGLWAFNDDWRSAFYVPAIFATLVAVFIWATLRD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPQSCGLPAIEEYKNDYPDDYDKSHENEMTAKEIFFKYVFNNKLLWSIAIANAFVYLIRY
CHHHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GVLDWAPVYLKEAKGFTVDKSSWAYFLYEWAGIPGTLLCGWISDKVFKGRRAPAGILFMV
HHHCCCHHHHHHCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LVTAAVLVYWFNPAGNPTIDMIALVAIGFLIYGPVMLIGLYALELVPKKAAGTAAGLTGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FGYLGGAVTANIVLGYTVDHFGWDGGFMILVASCVLSIMCLCYAFLGERAHHKAKDKEQA
HHHHHHHHHHHEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TIS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]