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The map label for this gene is pheC [H]

Identifier: 209695039

GI number: 209695039

Start: 1634685

End: 1635446

Strand: Reverse

Name: pheC [H]

Synonym: VSAL_I1534

Alternate gene names: 209695039

Gene position: 1635446-1634685 (Counterclockwise)

Preceding gene: 209695042

Following gene: 209695031

Centisome position: 49.18

GC content: 38.19

Gene sequence:

>762_bases
ATGCAAAAGAAACTATTATGCCTTTCAGTATTGCTTGCTGCTTCATGTTCAGCACAAGCAGATAGATTAGATGACATTCA
AGAATCCGGCGTCATTCGTGTCGGCACAACGGGCGACTATAAACCCTTCTCTTCCTTCGATGGAAAAAACTATACAGGGT
ATGACATTGATGTTGCTAAACACATCGCAGATCAATTAGGTGTAAAGCTTGAATTAGTTAAAACGTCTTGGAAAAACCTT
ATTCCAGATCTAAATGCAGATAAATATGACATTGCAATGGGTGGAATAACACGAAAAATGCAACGCCAATTACACGCAGA
ACAAACTCAAGGTTATATGACGTTTGGAAAGTGCTTTCTTGTTGCTAAAGGAAAAGCCGACGCATTCAATACCATCGATA
AAGTGAACATGAAAGAAGTACGTGTTGGCATCAATATTGGTGGTACCAATGAAATTTTTGCAGACGCTCATCTACAAAAT
GCGACCTTTACACGTTATGAGAATAATCTTGATGTCCCACAAGCCGTCGCCACTGGTAAAGTTGATGTCATGGTAACCGA
AACACCTGAAGCATTATTTTATCAAGCAACCGATAAACGATTGGAAGCCGCGCGTTGTGAGACCCCATTTACTAAAAGCC
AATTCGGCTATCTTGTCCCTAAAGGAGAGCAAGAACTCTTAAATACGGTTAATTTCATTATGGATGAAATGAAATTAAAA
AATATTGATGAACAGTTTATGAAAAACAACTCATTAAGATAA

Upstream 100 bases:

>100_bases
TAAAATATGTTTTTTTATGGTTACTGACTGAATGGTTTGATGTGTTACTTTAACAAAAGGTGATAGATTTGTTATCTAAC
TTAATCAATAAAAATATCTT

Downstream 100 bases:

>100_bases
CGTCACGCTATAAATATTTGCCTTAATTCTCTTAATTATGATTAGCAGACTTACTGGAGGTGAGTGTTTTACCTCCTTTT
GACCTCAATTCAATTTCCAT

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQKKLLCLSVLLAASCSAQADRLDDIQESGVIRVGTTGDYKPFSSFDGKNYTGYDIDVAKHIADQLGVKLELVKTSWKNL
IPDLNADKYDIAMGGITRKMQRQLHAEQTQGYMTFGKCFLVAKGKADAFNTIDKVNMKEVRVGINIGGTNEIFADAHLQN
ATFTRYENNLDVPQAVATGKVDVMVTETPEALFYQATDKRLEAARCETPFTKSQFGYLVPKGEQELLNTVNFIMDEMKLK
NIDEQFMKNNSLR

Sequences:

>Translated_253_residues
MQKKLLCLSVLLAASCSAQADRLDDIQESGVIRVGTTGDYKPFSSFDGKNYTGYDIDVAKHIADQLGVKLELVKTSWKNL
IPDLNADKYDIAMGGITRKMQRQLHAEQTQGYMTFGKCFLVAKGKADAFNTIDKVNMKEVRVGINIGGTNEIFADAHLQN
ATFTRYENNLDVPQAVATGKVDVMVTETPEALFYQATDKRLEAARCETPFTKSQFGYLVPKGEQELLNTVNFIMDEMKLK
NIDEQFMKNNSLR
>Mature_253_residues
MQKKLLCLSVLLAASCSAQADRLDDIQESGVIRVGTTGDYKPFSSFDGKNYTGYDIDVAKHIADQLGVKLELVKTSWKNL
IPDLNADKYDIAMGGITRKMQRQLHAEQTQGYMTFGKCFLVAKGKADAFNTIDKVNMKEVRVGINIGGTNEIFADAHLQN
ATFTRYENNLDVPQAVATGKVDVMVTETPEALFYQATDKRLEAARCETPFTKSQFGYLVPKGEQELLNTVNFIMDEMKLK
NIDEQFMKNNSLR

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=239, Percent_Identity=26.3598326359833, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787031, Length=231, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788649, Length=190, Percent_Identity=27.8947368421053, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28301; Mature: 28301

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKLLCLSVLLAASCSAQADRLDDIQESGVIRVGTTGDYKPFSSFDGKNYTGYDIDVAK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
HIADQLGVKLELVKTSWKNLIPDLNADKYDIAMGGITRKMQRQLHAEQTQGYMTFGKCFL
HHHHHHCCEEEEHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEE
VAKGKADAFNTIDKVNMKEVRVGINIGGTNEIFADAHLQNATFTRYENNLDVPQAVATGK
EECCCCCHHHHHHHCCHHHEEEEEEECCCCCEEECCCCCCCEEEEECCCCCCCHHHHCCC
VDVMVTETPEALFYQATDKRLEAARCETPFTKSQFGYLVPKGEQELLNTVNFIMDEMKLK
EEEEEECCCHHEEEHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHH
NIDEQFMKNNSLR
CHHHHHHHCCCCC
>Mature Secondary Structure
MQKKLLCLSVLLAASCSAQADRLDDIQESGVIRVGTTGDYKPFSSFDGKNYTGYDIDVAK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
HIADQLGVKLELVKTSWKNLIPDLNADKYDIAMGGITRKMQRQLHAEQTQGYMTFGKCFL
HHHHHHCCEEEEHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEE
VAKGKADAFNTIDKVNMKEVRVGINIGGTNEIFADAHLQNATFTRYENNLDVPQAVATGK
EECCCCCHHHHHHHCCHHHEEEEEEECCCCCEEECCCCCCCEEEEECCCCCCCHHHHCCC
VDVMVTETPEALFYQATDKRLEAARCETPFTKSQFGYLVPKGEQELLNTVNFIMDEMKLK
EEEEEECCCHHEEEHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHH
NIDEQFMKNNSLR
CHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]