BacMap

Definition	Aliivibrio salmonicida LFI1238 chromosome 1, complete genome.
Accession	NC_011312
Length	3,325,165

Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 209694994

GI number: 209694994

Start: 1594166

End: 1594882

Strand: Reverse

Name: fabG [C]

Synonym: VSAL_I1484

Alternate gene names: 209694994

Gene position: 1594882-1594166 (Counterclockwise)

Preceding gene: 209695000

Following gene: 209694983

Centisome position: 47.96

GC content: 39.75

Gene sequence:

>717_bases
ATGGTTATGTCTAAATTGGCACTAATTACGGGAGCAAGTCGAGGTATAGGAAAAGCGATTTCTCACTACTTTGCTCAGCA
AGGTTATTCACTTATTTTAGTCTCATTAAATAAAGACAACCTCAATGCCACAAAATTAGAGTTAGAAGCCCACTACCCGT
CGAGTTGCATCGAAACCATCAGCGTCGATTTTAATAACCCCGCAGACGTTGAATCTGCCATCTCTTCAATCATTGCTGAG
CATAGCTCTATCGATGTAATGGTAAACAGCGCAGGTGTTCTCATGGCAGGACACACGAACTTAACGCTAAAGCAGCTTTC
TGAATTAATAAACGTAAATCTACTTTCTACGATTACGGCCTGTAATTTGGTTATCGAAAAAATGAAACAACAAGGCTATG
GTGAGATTTATAATATTGGATCAACCGCAGGTTTAGAACCCGTACCAAAGATCGCCGCGTACTCTGCCACAAAAGCCGCT
ATTGTGAGTTATAGCCAATCGCTTTATCACGAACTTCTTCCCTTTAATATAAAGGTATGTTGTTTATGTCCAAGCGTTGT
CGATACTGACATGACCAACGATGGCCGTATTATGAACAACCTAAAAATCGAAACTCAAGATTTAACTAAAGCCATCGATT
TTATACGCAACTTGTCGCCAAGTGCCAGTATGTCGACACTCTCTATACGTTGTAAAACCATTGATTTAGAAAAGTAA

Upstream 100 bases:

>100_bases
TGCTAAAAGTAAAGAGAAAACCAATAAATGCCAGAGAGATATTGTCTCTTTTATAAAATAGAAGAAAATGATATGGTGCA
AAAACTCATTCAACAAGGAG

Downstream 100 bases:

>100_bases
TTATTTCAATTTGGTAGAGAACATCAGATAGAATAGACAATGAAAATAATCACCGTTAACTGATTATTATTCAATCAACT
TACGCTTCATTCTCATCGCA

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MVMSKLALITGASRGIGKAISHYFAQQGYSLILVSLNKDNLNATKLELEAHYPSSCIETISVDFNNPADVESAISSIIAE
HSSIDVMVNSAGVLMAGHTNLTLKQLSELINVNLLSTITACNLVIEKMKQQGYGEIYNIGSTAGLEPVPKIAAYSATKAA
IVSYSQSLYHELLPFNIKVCCLCPSVVDTDMTNDGRIMNNLKIETQDLTKAIDFIRNLSPSASMSTLSIRCKTIDLEK

Sequences:

>Translated_238_residues
MVMSKLALITGASRGIGKAISHYFAQQGYSLILVSLNKDNLNATKLELEAHYPSSCIETISVDFNNPADVESAISSIIAE
HSSIDVMVNSAGVLMAGHTNLTLKQLSELINVNLLSTITACNLVIEKMKQQGYGEIYNIGSTAGLEPVPKIAAYSATKAA
IVSYSQSLYHELLPFNIKVCCLCPSVVDTDMTNDGRIMNNLKIETQDLTKAIDFIRNLSPSASMSTLSIRCKTIDLEK
>Mature_238_residues
MVMSKLALITGASRGIGKAISHYFAQQGYSLILVSLNKDNLNATKLELEAHYPSSCIETISVDFNNPADVESAISSIIAE
HSSIDVMVNSAGVLMAGHTNLTLKQLSELINVNLLSTITACNLVIEKMKQQGYGEIYNIGSTAGLEPVPKIAAYSATKAA
IVSYSQSLYHELLPFNIKVCCLCPSVVDTDMTNDGRIMNNLKIETQDLTKAIDFIRNLSPSASMSTLSIRCKTIDLEK

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=197, Percent_Identity=30.4568527918782, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI109715829, Length=219, Percent_Identity=30.5936073059361, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=31.7460317460317, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4557649, Length=194, Percent_Identity=31.4432989690722, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI226371731, Length=201, Percent_Identity=28.8557213930348, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=230, Percent_Identity=24.7826086956522, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705855, Length=194, Percent_Identity=30.4123711340206, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI210032110, Length=220, Percent_Identity=26.3636363636364, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=28.4974093264249, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4758504, Length=203, Percent_Identity=30.5418719211823, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI126723750, Length=233, Percent_Identity=24.8927038626609, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=237, Percent_Identity=24.4725738396624, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504503, Length=218, Percent_Identity=23.394495412844, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=193, Percent_Identity=31.0880829015544, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=27.4261603375527, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=32.4607329842932, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788459, Length=191, Percent_Identity=27.2251308900524, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=27.8884462151394, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=189, Percent_Identity=26.4550264550265, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87082160, Length=230, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786701, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=25.7894736842105, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=193, Percent_Identity=26.9430051813472, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25152911, Length=200, Percent_Identity=29, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI212646214, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532725, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=203, Percent_Identity=26.1083743842365, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=192, Percent_Identity=28.125, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17557668, Length=245, Percent_Identity=27.3469387755102, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=188, Percent_Identity=27.1276595744681, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=198, Percent_Identity=26.7676767676768, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.8943089430894, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=25.5102040816327, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=26.9430051813472, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=27.5510204081633, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557780, Length=218, Percent_Identity=24.7706422018349, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=28.1407035175879, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=26.1306532663317, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=27.4611398963731, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=26.3681592039801, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319635, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=26.5625, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=198, Percent_Identity=25.2525252525253, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21357041, Length=239, Percent_Identity=30.1255230125523, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=31.25, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=30.6878306878307, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=31.4432989690722, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=32.1243523316062, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=32.1243523316062, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=26.2886597938144, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007236, Length=237, Percent_Identity=24.4725738396624, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221331218, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24665243, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=29.4416243654822, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=29.7435897435897, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=28.921568627451, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=27.979274611399, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=191, Percent_Identity=30.3664921465969, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331216, Length=191, Percent_Identity=30.3664921465969, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641232, Length=240, Percent_Identity=22.5, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648944, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=28.0612244897959, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281364494, Length=248, Percent_Identity=26.2096774193548, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=23.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=23.5897435897436, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=24.5901639344262, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364892, Length=207, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25751; Mature: 25751

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSKLALITGASRGIGKAISHYFAQQGYSLILVSLNKDNLNATKLELEAHYPSSCIETI
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHEE
SVDFNNPADVESAISSIIAEHSSIDVMVNSAGVLMAGHTNLTLKQLSELINVNLLSTITA
EECCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCHHHHHHHH
CNLVIEKMKQQGYGEIYNIGSTAGLEPVPKIAAYSATKAAIVSYSQSLYHELLPFNIKVC
HHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
CLCPSVVDTDMTNDGRIMNNLKIETQDLTKAIDFIRNLSPSASMSTLSIRCKTIDLEK
EEECHHHCCCCCCCCEEEECCEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure
MVMSKLALITGASRGIGKAISHYFAQQGYSLILVSLNKDNLNATKLELEAHYPSSCIETI
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHEE
SVDFNNPADVESAISSIIAEHSSIDVMVNSAGVLMAGHTNLTLKQLSELINVNLLSTITA
EECCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCHHHHHHHH
CNLVIEKMKQQGYGEIYNIGSTAGLEPVPKIAAYSATKAAIVSYSQSLYHELLPFNIKVC
HHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
CLCPSVVDTDMTNDGRIMNNLKIETQDLTKAIDFIRNLSPSASMSTLSIRCKTIDLEK
EEECHHHCCCCCCCCEEEECCEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]