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The map label for this gene is murQ

Identifier: 209694801

GI number: 209694801

Start: 1369405

End: 1370307

Strand: Direct

Name: murQ

Synonym: VSAL_I1260

Alternate gene names: 209694801

Gene position: 1369405-1370307 (Clockwise)

Preceding gene: 209694799

Following gene: 209694802

Centisome position: 41.18

GC content: 43.85

Gene sequence:

>903_bases
ATGAAAATTGATCTAACCACATTGGTAACAGAAAGCCGTAATCAAGCAAGTGAGCAAATAGATGTGTTATCAACCGTAGA
AATGTTGACGGTTATTAATAAAGAAGACCAGAAAGTGGCGTTAGCCGTTGAAGCTATTTTGCCTCAAATCGCTGAAGTTG
TAGATGCAATTGCTGTGGCGTTTCAATGTGGTGGGCGTTTGATTTATATCGGTGCAGGCACATCTGGCCGCTTAGGTATT
TTGGATGCAAGTGAATGCCCTCCAACCTACGGCTCTAATCCTGACCTGGTTGTGGGTTTAATTGCTGGCGGTCATAAAGC
GATTTTAAAAGCAGTAGAAAATGCAGAAGACAACCGTGAATTAGGCGCATCAGATCTGCAAGATTTGGGATTGAACGAGA
AAGACGTGCTAGTGGGTATTGCCGCGAGTGGACGTACTCCTTATGTTCTTGGTGCGATGGCATACGCAAAATCAGTCGGT
GCAACCGTAGCAACGCTGAGTTGTAACCCAAATAGCCCAATGACAGAACTGGCAGACATCAATATGACACCAGTTGTTGG
CCCTGAAATCGTAACTGGCTCTTCTCGTATGAAAGCCGGAACGGCTCAAAAATTGGTTCTGAACATGTTAACAACCGGAG
CGATGATCCGCACTGGTAAAGTATTTGGTAACTTGATGGTTGATGTCGAAGCAACCAATGCAAAATTAGTACAGAGACAA
AAGAATATTGTTATTGAGGCTACGGGCTGTTCAGAAACGGAAGCCGCAGAGTCGTTATCTCAATGTAATAACCACTGTAA
GACAGCGATTCTTATTGTGTTGTCTGGGCTCGATGCGAAAAGTGCGACAGACAAATTGACGGAATATAATGGATTTATTC
GCGATGCACTCGCTAATAGCTAA

Upstream 100 bases:

>100_bases
AATAACTTTTGTTGTGATTTTGGTCACTAAATGGAATTTTTTATTCTTTATGATGGCAACCATTGAAATTGAGAATTTAT
CTTTTGAAGAGAACGCCATT

Downstream 100 bases:

>100_bases
CCAGACTATGCAGATCAATATGGTCTGCAATAGCCTCTAGATTGAGAAAGGAAAATGGCATGGCCAAGATAACGACATCA
ATGGTACAAGAGATATTAAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKIDLTTLVTESRNQASEQIDVLSTVEMLTVINKEDQKVALAVEAILPQIAEVVDAIAVAFQCGGRLIYIGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMAYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEIVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSETEAAESLSQCNNHCKTAILIVLSGLDAKSATDKLTEYNGFIRDALANS

Sequences:

>Translated_300_residues
MKIDLTTLVTESRNQASEQIDVLSTVEMLTVINKEDQKVALAVEAILPQIAEVVDAIAVAFQCGGRLIYIGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMAYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEIVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSETEAAESLSQCNNHCKTAILIVLSGLDAKSATDKLTEYNGFIRDALANS
>Mature_300_residues
MKIDLTTLVTESRNQASEQIDVLSTVEMLTVINKEDQKVALAVEAILPQIAEVVDAIAVAFQCGGRLIYIGAGTSGRLGI
LDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRELGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMAYAKSVG
ATVATLSCNPNSPMTELADINMTPVVGPEIVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
KNIVIEATGCSETEAAESLSQCNNHCKTAILIVLSGLDAKSATDKLTEYNGFIRDALANS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=59.3220338983051, Blast_Score=350, Evalue=7e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_ALISL (B6EJZ8)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262729.1
- ProteinModelPortal:   B6EJZ8
- GeneID:   6986942
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1260
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31365; Mature: 31365

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 85-85 ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDLTTLVTESRNQASEQIDVLSTVEMLTVINKEDQKVALAVEAILPQIAEVVDAIAVA
CEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FQCGGRLIYIGAGTSGRLGILDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRE
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCHH
LGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMAYAKSVGATVATLSCNPNSPMTELADI
CCCHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHCC
NMTPVVGPEIVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
CCCCCCCCEEECCCCHHCCCHHHHHHHHHHHCCHHEEECCEEEEEEEEEECCCHHHHHHC
KNIVIEATGCSETEAAESLSQCNNHCKTAILIVLSGLDAKSATDKLTEYNGFIRDALANS
CCEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIDLTTLVTESRNQASEQIDVLSTVEMLTVINKEDQKVALAVEAILPQIAEVVDAIAVA
CEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FQCGGRLIYIGAGTSGRLGILDASECPPTYGSNPDLVVGLIAGGHKAILKAVENAEDNRE
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCHH
LGASDLQDLGLNEKDVLVGIAASGRTPYVLGAMAYAKSVGATVATLSCNPNSPMTELADI
CCCHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHCC
NMTPVVGPEIVTGSSRMKAGTAQKLVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLVQRQ
CCCCCCCCEEECCCCHHCCCHHHHHHHHHHHCCHHEEECCEEEEEEEEEECCCHHHHHHC
KNIVIEATGCSETEAAESLSQCNNHCKTAILIVLSGLDAKSATDKLTEYNGFIRDALANS
CCEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA