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The map label for this gene is yfbQ [H]

Identifier: 209694655

GI number: 209694655

Start: 1192485

End: 1193699

Strand: Reverse

Name: yfbQ [H]

Synonym: VSAL_I1097

Alternate gene names: 209694655

Gene position: 1193699-1192485 (Counterclockwise)

Preceding gene: 209694663

Following gene: 209694652

Centisome position: 35.9

GC content: 40.99

Gene sequence:

>1215_bases
ATGCAAAATATTGCAATGTCATCAAAACTTAGCAGTGTATGCTACGACATTCGCGGTCCTGTTCTTAAACATGCTAAAAG
AATGGAAGAAGAAGGGCAGAAAATTCTTAAACTAAACATTGGGAATCCCGCCCAGTTTGGTTTTGACGCCCCTGAAGAAA
TCCTTGTTGATGTAATTAAAAACCTACCAACCTCACAAGGTTACGGTGACTCAAAAGGCATTTATTCAGCGCGTAAAGCG
GTTGTACAACACTATCAACGTCGTGGTTTATTAGATCTTGACGTCGAAGATGTGTACATCGGTAACGGGGCTTCTGAATT
AATCGTAATGGCAATGCAAGCGTTACTTAACAATGGCGACGAAATGCTGGTTCCTGCTCCTGACTATCCTTTATGGACTG
CGGCAGTATCGTTATCTGGTGGTAATCCTGTTCATTACTTATGTGATGAAGGTGCTGATTGGTACCCAGATCTTGACGAC
ATCAAAAAGAAAATCACACCGAACACCAAAGGGATTGTATTAATTAACCCAAACAATCCAACCGGTGCGGTATACAGCCG
TGACTTCTTATTGCAAATAGTCGAAATTGCTCGTCAAAACAATTTGATCATTTTTGCTGATGAAATTTATGACAAAGTTC
TTTATGACGGCGCAATTCACACGACATTGGCGACACTAGCACCCGATTTACTTACCGTAACATTTAACGGTTTATCTAAA
GCTTATCGTGTTTGTGGTTTCCGTGGTGGCTGGATGTTCTTGAATGGCCCTAAAGATCATGCTCAAGGGTATATTGCAGG
TCTTGATATGTTGGCTTCAATGCGCTTATGTGCCAACGTACCAATGCAGCATGCTATTCAAACCGCATTGGGTGGTTATC
AAAGTATTAATGAACTTCTGCTTCCGGGTGGTCGTTTATTGGAGCAACGTGATAAAGCGTATGAATTAATCACACAAATT
CCAGGCGTGAGTTGTGTTAAGCCAAAGGGCGCAATGTACTTGTTTCCTAAACTTGATCCTAAGATGTATAAAATTAAAGA
TGACCAAAAATTCGTACTGGATTTCTTGATCAAAGAAAAAGTATTACTCGTTCAAGGTACCGGTTTTAACTGGCCAACAC
CTGATCACTTCCGTATCGTTACACTGCCTCGCGTAGATGACTTAGAAGTTGCGATCGGACGCTTAGAGCGTTTCTTACAT
ACTTATAAGCAATAA

Upstream 100 bases:

>100_bases
AGCCATTTTTACACGATTTTTTTCTAAAAATTGTTTCTCAGTCTATAAGAAATAGTGTAATTTGGGCTTATATCGTTTTT
TATATCAACAAGGTTAAACC

Downstream 100 bases:

>100_bases
TAAATACGTACTAAACAAACGAAGGTCTGCATAATTGCAGACCTTTTTTTTATTCAAAAAAAATAACTCAACGCTCTCGC
ACAAAATGATTCTGAACGAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQNIAMSSKLSSVCYDIRGPVLKHAKRMEEEGQKILKLNIGNPAQFGFDAPEEILVDVIKNLPTSQGYGDSKGIYSARKA
VVQHYQRRGLLDLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVSLSGGNPVHYLCDEGADWYPDLDD
IKKKITPNTKGIVLINPNNPTGAVYSRDFLLQIVEIARQNNLIIFADEIYDKVLYDGAIHTTLATLAPDLLTVTFNGLSK
AYRVCGFRGGWMFLNGPKDHAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELLLPGGRLLEQRDKAYELITQI
PGVSCVKPKGAMYLFPKLDPKMYKIKDDQKFVLDFLIKEKVLLVQGTGFNWPTPDHFRIVTLPRVDDLEVAIGRLERFLH
TYKQ

Sequences:

>Translated_404_residues
MQNIAMSSKLSSVCYDIRGPVLKHAKRMEEEGQKILKLNIGNPAQFGFDAPEEILVDVIKNLPTSQGYGDSKGIYSARKA
VVQHYQRRGLLDLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVSLSGGNPVHYLCDEGADWYPDLDD
IKKKITPNTKGIVLINPNNPTGAVYSRDFLLQIVEIARQNNLIIFADEIYDKVLYDGAIHTTLATLAPDLLTVTFNGLSK
AYRVCGFRGGWMFLNGPKDHAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELLLPGGRLLEQRDKAYELITQI
PGVSCVKPKGAMYLFPKLDPKMYKIKDDQKFVLDFLIKEKVLLVQGTGFNWPTPDHFRIVTLPRVDDLEVAIGRLERFLH
TYKQ
>Mature_404_residues
MQNIAMSSKLSSVCYDIRGPVLKHAKRMEEEGQKILKLNIGNPAQFGFDAPEEILVDVIKNLPTSQGYGDSKGIYSARKA
VVQHYQRRGLLDLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVSLSGGNPVHYLCDEGADWYPDLDD
IKKKITPNTKGIVLINPNNPTGAVYSRDFLLQIVEIARQNNLIIFADEIYDKVLYDGAIHTTLATLAPDLLTVTFNGLSK
AYRVCGFRGGWMFLNGPKDHAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELLLPGGRLLEQRDKAYELITQI
PGVSCVKPKGAMYLFPKLDPKMYKIKDDQKFVLDFLIKEKVLLVQGTGFNWPTPDHFRIVTLPRVDDLEVAIGRLERFLH
TYKQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=467, Percent_Identity=25.9100642398287, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=26.6304347826087, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=28.6842105263158, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=24.8888888888889, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI95147551, Length=183, Percent_Identity=28.9617486338798, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169881279, Length=183, Percent_Identity=28.9617486338798, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713256, Length=313, Percent_Identity=24.2811501597444, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56713254, Length=313, Percent_Identity=24.2811501597444, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881281, Length=271, Percent_Identity=24.7232472324723, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=76.2376237623762, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=27.3684210526316, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786816, Length=240, Percent_Identity=22.9166666666667, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=30.0268096514745, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=469, Percent_Identity=26.226012793177, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981215, Length=297, Percent_Identity=27.9461279461279, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=172, Percent_Identity=34.3023255813954, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=172, Percent_Identity=34.3023255813954, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=165, Percent_Identity=29.6969696969697, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=469, Percent_Identity=26.6524520255864, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=460, Percent_Identity=26.0869565217391, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=354, Percent_Identity=25.9887005649718, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=27.0053475935829, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24641770, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641760, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641768, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641766, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641764, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI45551451, Length=468, Percent_Identity=25.6410256410256, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28573069, Length=269, Percent_Identity=27.5092936802974, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646114, Length=269, Percent_Identity=27.5092936802974, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573067, Length=269, Percent_Identity=27.5092936802974, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573065, Length=269, Percent_Identity=27.5092936802974, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45018; Mature: 45018

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIAMSSKLSSVCYDIRGPVLKHAKRMEEEGQKILKLNIGNPAQFGFDAPEEILVDVIK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYGDSKGIYSARKAVVQHYQRRGLLDLDVEDVYIGNGASELIVMAMQALLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSGGNPVHYLCDEGADWYPDLDDIKKKITPNTKGIVLINPNNP
EEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLQIVEIARQNNLIIFADEIYDKVLYDGAIHTTLATLAPDLLTVTFNGLSK
CCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHEEEEHHHHHH
AYRVCGFRGGWMFLNGPKDHAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELL
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDKAYELITQIPGVSCVKPKGAMYLFPKLDPKMYKIKDDQKFVLDFLIKEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCC
VLLVQGTGFNWPTPDHFRIVTLPRVDDLEVAIGRLERFLHTYKQ
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNIAMSSKLSSVCYDIRGPVLKHAKRMEEEGQKILKLNIGNPAQFGFDAPEEILVDVIK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYGDSKGIYSARKAVVQHYQRRGLLDLDVEDVYIGNGASELIVMAMQALLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSGGNPVHYLCDEGADWYPDLDDIKKKITPNTKGIVLINPNNP
EEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLQIVEIARQNNLIIFADEIYDKVLYDGAIHTTLATLAPDLLTVTFNGLSK
CCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHEEEEHHHHHH
AYRVCGFRGGWMFLNGPKDHAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELL
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDKAYELITQIPGVSCVKPKGAMYLFPKLDPKMYKIKDDQKFVLDFLIKEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCC
VLLVQGTGFNWPTPDHFRIVTLPRVDDLEVAIGRLERFLHTYKQ
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]