Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 209694547

GI number: 209694547

Start: 1086892

End: 1088013

Strand: Reverse

Name: mrdB [H]

Synonym: VSAL_I0984

Alternate gene names: 209694547

Gene position: 1088013-1086892 (Counterclockwise)

Preceding gene: 209694548

Following gene: 209694546

Centisome position: 32.72

GC content: 41.0

Gene sequence:

>1122_bases
ATGAGAGTTGATATCGCATCAGGAAAAAATCGTGACTTTTTCCATCGAATTCATATAGATTTGCCCTTACTGCTTGGCAT
CTTATTATTAATGGCTTGTGCTCTTGTCATTATGTACAGTGCCAGCGGGCAAAGCTTATTGATGATGGATAAGCAAGCAA
TGCGAATGTTACTCTCCTTAGGCGTTATGGCTTTACTTGCCCAAATACCACCAAGAACTTATGAGGTCGCTGCACCTTAT
CTCTTTGCTATTGGTGTTATCTTATTATTAGGGGTTTTATTCTTTGGTGAATCCTCTAAAGGCGCTCAACGTTGGTTAAA
CTTAGGATTTGTTCGTTTTCAACCTTCGGAATTAATTAAGCTCGCCGTTCCCTTAATGATTGCCAGATATATAGGTAATA
AACCTCTTCCTCCAACGGTTCGTACCTTGTTTATCGCGTTATTGATGGTATTTGTTCCTACCATTATGATCGCCAAACAG
CCCGATTTAGGTACTTCTATCTTAATCGCAGCTTCAGGTGTTTTTGTTATCTTTCTAGCGGGCATTAGTTGGAAAATAAT
TACTGCCGCCGCCATTGCGGTTGGGGGGTTTATTCCTATCCTATGGTTCTTTTTGATGCGGCCTTACCAAAAAGTAAGGG
TTGAGACATTATTTAACCCAGAATCTGATCCTTTAGGCGCTGGCTATCACATTATCCAATCTAAAATTGCTATCGGTTCA
GGAGGGTTATTCGGCAAAGGGTGGTTGCATGGTACCCAGTCTCAACTCGAATTTATTCCTGAGCGCCATACTGATTTCAT
TTTTGCCGTTATCGCAGAAGAATGGGGACTCATTGGAGTCATGGTATTGCTCACGATCTATTTATTCATTATTGGCCGAG
GATTATTCTTAGCAAGCCAAGCCCAAACTGCTTTTGGACGAATGATGGGGGGCAGTGTCGTTTTAAGCTTTTTTGTTTAT
ATTTTTGTAAACATAGGCATGGTTAGTGGTATTTTGCCCGTCGTTGGCGTTCCTCTTCCCCTCGTTAGTTATGGCGGTAC
ATCAATGGTAACGTTGATGGCAGGATTTGGCATTTTAATGTCAATACACACACATAAAAAAATACACTCCAAGGCAAACT
AA

Upstream 100 bases:

>100_bases
TTGAAAATGGCGGCGGCGGTTCTAGCCAAGGCGGCCCAATTGCACGAAGTGTATTTGACCATGTGTTATTACCAGCAACA
GGAGAGGTGAGTAATAAATA

Downstream 100 bases:

>100_bases
CTCATGCGTATTCTTCTACTGGTTATTTCTCTTATTTTGGTTGGTTGTGCTTCTGAACCACCAATAAAAAATACAGATGA
GCCTAATGCAGGGCGTTATC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRVDIASGKNRDFFHRIHIDLPLLLGILLLMACALVIMYSASGQSLLMMDKQAMRMLLSLGVMALLAQIPPRTYEVAAPY
LFAIGVILLLGVLFFGESSKGAQRWLNLGFVRFQPSELIKLAVPLMIARYIGNKPLPPTVRTLFIALLMVFVPTIMIAKQ
PDLGTSILIAASGVFVIFLAGISWKIITAAAIAVGGFIPILWFFLMRPYQKVRVETLFNPESDPLGAGYHIIQSKIAIGS
GGLFGKGWLHGTQSQLEFIPERHTDFIFAVIAEEWGLIGVMVLLTIYLFIIGRGLFLASQAQTAFGRMMGGSVVLSFFVY
IFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILMSIHTHKKIHSKAN

Sequences:

>Translated_373_residues
MRVDIASGKNRDFFHRIHIDLPLLLGILLLMACALVIMYSASGQSLLMMDKQAMRMLLSLGVMALLAQIPPRTYEVAAPY
LFAIGVILLLGVLFFGESSKGAQRWLNLGFVRFQPSELIKLAVPLMIARYIGNKPLPPTVRTLFIALLMVFVPTIMIAKQ
PDLGTSILIAASGVFVIFLAGISWKIITAAAIAVGGFIPILWFFLMRPYQKVRVETLFNPESDPLGAGYHIIQSKIAIGS
GGLFGKGWLHGTQSQLEFIPERHTDFIFAVIAEEWGLIGVMVLLTIYLFIIGRGLFLASQAQTAFGRMMGGSVVLSFFVY
IFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILMSIHTHKKIHSKAN
>Mature_373_residues
MRVDIASGKNRDFFHRIHIDLPLLLGILLLMACALVIMYSASGQSLLMMDKQAMRMLLSLGVMALLAQIPPRTYEVAAPY
LFAIGVILLLGVLFFGESSKGAQRWLNLGFVRFQPSELIKLAVPLMIARYIGNKPLPPTVRTLFIALLMVFVPTIMIAKQ
PDLGTSILIAASGVFVIFLAGISWKIITAAAIAVGGFIPILWFFLMRPYQKVRVETLFNPESDPLGAGYHIIQSKIAIGS
GGLFGKGWLHGTQSQLEFIPERHTDFIFAVIAEEWGLIGVMVLLTIYLFIIGRGLFLASQAQTAFGRMMGGSVVLSFFVY
IFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILMSIHTHKKIHSKAN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=364, Percent_Identity=61.2637362637363, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1786277, Length=376, Percent_Identity=31.6489361702128, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40731; Mature: 40731

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVDIASGKNRDFFHRIHIDLPLLLGILLLMACALVIMYSASGQSLLMMDKQAMRMLLSL
CEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
GVMALLAQIPPRTYEVAAPYLFAIGVILLLGVLFFGESSKGAQRWLNLGFVRFQPSELIK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEEECHHHHHH
LAVPLMIARYIGNKPLPPTVRTLFIALLMVFVPTIMIAKQPDLGTSILIAASGVFVIFLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
GISWKIITAAAIAVGGFIPILWFFLMRPYQKVRVETLFNPESDPLGAGYHIIQSKIAIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHEECC
GGLFGKGWLHGTQSQLEFIPERHTDFIFAVIAEEWGLIGVMVLLTIYLFIIGRGLFLASQ
CCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHH
AQTAFGRMMGGSVVLSFFVYIFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHH
SIHTHKKIHSKAN
HHHHHHHHHCCCC
>Mature Secondary Structure
MRVDIASGKNRDFFHRIHIDLPLLLGILLLMACALVIMYSASGQSLLMMDKQAMRMLLSL
CEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
GVMALLAQIPPRTYEVAAPYLFAIGVILLLGVLFFGESSKGAQRWLNLGFVRFQPSELIK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEEECHHHHHH
LAVPLMIARYIGNKPLPPTVRTLFIALLMVFVPTIMIAKQPDLGTSILIAASGVFVIFLA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
GISWKIITAAAIAVGGFIPILWFFLMRPYQKVRVETLFNPESDPLGAGYHIIQSKIAIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHEECC
GGLFGKGWLHGTQSQLEFIPERHTDFIFAVIAEEWGLIGVMVLLTIYLFIIGRGLFLASQ
CCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHH
AQTAFGRMMGGSVVLSFFVYIFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHH
SIHTHKKIHSKAN
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]