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The map label for this gene is dinB [H]

Identifier: 209694524

GI number: 209694524

Start: 1053775

End: 1054689

Strand: Direct

Name: dinB [H]

Synonym: VSAL_I0957

Alternate gene names: 209694524

Gene position: 1053775-1054689 (Clockwise)

Preceding gene: 209694523

Following gene: 209694525

Centisome position: 31.69

GC content: 39.02

Gene sequence:

>915_bases
GTGCGTAAAATCATTCATATTGATATGGATTGTTTCTATGCAGCGGTTGAAATGCGAGATAATCCTGTATTACGTGACGT
TCCTTTGGCCGTTGGTGGAAGTGAAAGACAGCGTGGTGTATTAAGTACGTGTAACTATCAAGCTAGGAAGTTTGGTCTTC
ATTCTGCAATGCCAACAGGACGTGCGTTATCCCTTTGTCCTCACTTAGTGGTTGTACCTGGTCGCATGCAGGTCTACAAG
CAAGTCTCTCATCATATACACCGTATATTTCGTCGCTATACCGATAAAATAGAACCACTCTCTTTAGATGAAGCTTATCT
CGATGTTAGTGAATGTACGTTGTTGCATGGTTCGGCGACATTGATAGCTCAACAAATACGTAGAGACATATTTAATGAAC
TGCAATTAACCGCATCAGCAGGAATTGCCCCTCTTAAATTTTTAGCTAAAATCGCTTCTGATTTAAATAAACCTGATGGT
CAGTATGTGATTACTCCGAATATGGTTATGGATGAAATTGACTCATTACCATTGGAGAAAATACCAGGGGTCGGAAAAGT
AAGCTTAGAGCGGTTACATCGATCAGGACTGCATACTTGCAAGGACGTCCAACAGTTTGACCAACGTGAATTATTATTGT
TATTTGGAAAAATGGGGGCTTCATTATGGAAGCGATCTCATGGAATTGATGAAAGAGAAGTGATTACAGAGCGTAATCGA
AAGTCCGTAGGCGTAGAAAGAACATTTTCTCATAATATCAGCATGTTTGAAGAATGCTGGGAAGTCATTAAAACACGCTT
GTATCCTGAATTAGAGTCGAGACTAATAAAAGCAAATGGTGATAATTATATTGCTAAGCAAGGTATTAAAATTAAGTTCG
CAGACTTCCAACATTTTCCTAATGCATGTTTTTAG

Upstream 100 bases:

>100_bases
ATTGTAAAAAAATCATTTCATCGCTATTATTTAACTGTGTATTTATACAGTTGATGTGAGTGTTGAGATTGAAAACGTGG
AATTAGAAGCAGATAAAAAG

Downstream 100 bases:

>100_bases
CTGATTTATTGTCAATGAATAACAGTATGTAAGTAATTATAATAATTAGCGCATAATGTACTAATAGTGTGTTTAATTCT
TAATTAACCTATTGTATGGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRKIIHIDMDCFYAAVEMRDNPVLRDVPLAVGGSERQRGVLSTCNYQARKFGLHSAMPTGRALSLCPHLVVVPGRMQVYK
QVSHHIHRIFRRYTDKIEPLSLDEAYLDVSECTLLHGSATLIAQQIRRDIFNELQLTASAGIAPLKFLAKIASDLNKPDG
QYVITPNMVMDEIDSLPLEKIPGVGKVSLERLHRSGLHTCKDVQQFDQRELLLLFGKMGASLWKRSHGIDEREVITERNR
KSVGVERTFSHNISMFEECWEVIKTRLYPELESRLIKANGDNYIAKQGIKIKFADFQHFPNACF

Sequences:

>Translated_304_residues
MRKIIHIDMDCFYAAVEMRDNPVLRDVPLAVGGSERQRGVLSTCNYQARKFGLHSAMPTGRALSLCPHLVVVPGRMQVYK
QVSHHIHRIFRRYTDKIEPLSLDEAYLDVSECTLLHGSATLIAQQIRRDIFNELQLTASAGIAPLKFLAKIASDLNKPDG
QYVITPNMVMDEIDSLPLEKIPGVGKVSLERLHRSGLHTCKDVQQFDQRELLLLFGKMGASLWKRSHGIDEREVITERNR
KSVGVERTFSHNISMFEECWEVIKTRLYPELESRLIKANGDNYIAKQGIKIKFADFQHFPNACF
>Mature_304_residues
MRKIIHIDMDCFYAAVEMRDNPVLRDVPLAVGGSERQRGVLSTCNYQARKFGLHSAMPTGRALSLCPHLVVVPGRMQVYK
QVSHHIHRIFRRYTDKIEPLSLDEAYLDVSECTLLHGSATLIAQQIRRDIFNELQLTASAGIAPLKFLAKIASDLNKPDG
QYVITPNMVMDEIDSLPLEKIPGVGKVSLERLHRSGLHTCKDVQQFDQRELLLLFGKMGASLWKRSHGIDEREVITERNR
KSVGVERTFSHNISMFEECWEVIKTRLYPELESRLIKANGDNYIAKQGIKIKFADFQHFPNACF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=326, Percent_Identity=30.3680981595092, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7706681, Length=327, Percent_Identity=29.6636085626911, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI154350220, Length=290, Percent_Identity=31.7241379310345, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=50, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI5729982, Length=356, Percent_Identity=26.9662921348315, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1786425, Length=298, Percent_Identity=66.1073825503356, Blast_Score=403, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI193205700, Length=307, Percent_Identity=31.5960912052117, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17537959, Length=288, Percent_Identity=29.1666666666667, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115534089, Length=127, Percent_Identity=37.7952755905512, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193205702, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=326, Percent_Identity=27.9141104294479, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=28.9752650176678, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=28.9752650176678, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=34.7457627118644, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 34661; Mature: 34661

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCFYAAVEMRDNPVLRDVPLAVGGSERQRGVLSTCNYQARKFGLHSAMPTG
CCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHCCHHHHHHHHHHCCCCC
RALSLCPHLVVVPGRMQVYKQVSHHIHRIFRRYTDKIEPLSLDEAYLDVSECTLLHGSAT
CHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCHHH
LIAQQIRRDIFNELQLTASAGIAPLKFLAKIASDLNKPDGQYVITPNMVMDEIDSLPLEK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCHHH
IPGVGKVSLERLHRSGLHTCKDVQQFDQRELLLLFGKMGASLWKRSHGIDEREVITERNR
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
KSVGVERTFSHNISMFEECWEVIKTRLYPELESRLIKANGDNYIAKQGIKIKFADFQHFP
HHCCCHHHHHCCHHHHHHHHHHHHHHCCHHHHHHEECCCCCCEEECCCCEEEEECHHCCC
NACF
CCCC
>Mature Secondary Structure
MRKIIHIDMDCFYAAVEMRDNPVLRDVPLAVGGSERQRGVLSTCNYQARKFGLHSAMPTG
CCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHCCHHHHHHHHHHCCCCC
RALSLCPHLVVVPGRMQVYKQVSHHIHRIFRRYTDKIEPLSLDEAYLDVSECTLLHGSAT
CHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCHHH
LIAQQIRRDIFNELQLTASAGIAPLKFLAKIASDLNKPDGQYVITPNMVMDEIDSLPLEK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCHHH
IPGVGKVSLERLHRSGLHTCKDVQQFDQRELLLLFGKMGASLWKRSHGIDEREVITERNR
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
KSVGVERTFSHNISMFEECWEVIKTRLYPELESRLIKANGDNYIAKQGIKIKFADFQHFP
HHCCCHHHHHCCHHHHHHHHHHHHHHCCHHHHHHEECCCCCCEEECCCCEEEEECHHCCC
NACF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA