Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 209694461

GI number: 209694461

Start: 988174

End: 988725

Strand: Reverse

Name: gmhB [H]

Synonym: VSAL_I0885

Alternate gene names: 209694461

Gene position: 988725-988174 (Counterclockwise)

Preceding gene: 209694465

Following gene: 209694460

Centisome position: 29.73

GC content: 40.4

Gene sequence:

>552_bases
TTGTCTAAACCAGCAATATTTATTGATAGAGATGGCGTGATTAACGTTGATCGTGGCTACGTTCATAAGCGTGATGACTT
TGAATACATTGATGGTGTGTTCGATGCTGTTAAGATATGCAAAGACATGGGCTACTTACTTGTATTAGTGACCAATCAAT
CAGGCATTGCACGTGGTATCTTTACTGAAGAGCAGTTTGAAACATTAACTGAATGGATGGATTGGAACTTTGCTGAGCAT
GACATCGATTTTGATGGCATTTACTATTGTCCGCATCACCCTGAAGCGACAGTAGAACAGTACAAAGAAGAGTGTGATTG
TCGTAAACCAAATCCTGGTATGTTCATGTCAGCTCAAAGCTTCTTAGATATCGACATGGAAAAATCTGTGATGATCGGTG
ATAAGAAAGAAGACATGATGGCAGCTCAAGTGGCTGGCGTTGGTACACGTATTCTTGTTCGTACGGGTAAACCTGTAACA
GAAGAAGGCGAAGCATTAGCAACAACGGTACTTGATAGTATTGCGGATGTGCCTAAGTTTTTATTTGCTTAA

Upstream 100 bases:

>100_bases
TTTTACGTCTAGACGGCTAAACGTATAAATAAGATGCTAATCATTTAAAAGCGTGAGATAATTTTATCATTAAGAGATTC
GACAATTAGAGGGTTTTACC

Downstream 100 bases:

>100_bases
TTAATACCGATACAATGAAATTTCAGACGCCTATAGAGAAATCTATAGGCGTTTTTTTTGATCTTTATTGGAACAAAGGT
CAAGTAATTGATTTATTAAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSKPAIFIDRDGVINVDRGYVHKRDDFEYIDGVFDAVKICKDMGYLLVLVTNQSGIARGIFTEEQFETLTEWMDWNFAEH
DIDFDGIYYCPHHPEATVEQYKEECDCRKPNPGMFMSAQSFLDIDMEKSVMIGDKKEDMMAAQVAGVGTRILVRTGKPVT
EEGEALATTVLDSIADVPKFLFA

Sequences:

>Translated_183_residues
MSKPAIFIDRDGVINVDRGYVHKRDDFEYIDGVFDAVKICKDMGYLLVLVTNQSGIARGIFTEEQFETLTEWMDWNFAEH
DIDFDGIYYCPHHPEATVEQYKEECDCRKPNPGMFMSAQSFLDIDMEKSVMIGDKKEDMMAAQVAGVGTRILVRTGKPVT
EEGEALATTVLDSIADVPKFLFA
>Mature_182_residues
SKPAIFIDRDGVINVDRGYVHKRDDFEYIDGVFDAVKICKDMGYLLVLVTNQSGIARGIFTEEQFETLTEWMDWNFAEHD
IDFDGIYYCPHHPEATVEQYKEECDCRKPNPGMFMSAQSFLDIDMEKSVMIGDKKEDMMAAQVAGVGTRILVRTGKPVTE
EGEALATTVLDSIADVPKFLFA

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=180, Percent_Identity=64.4444444444444, Blast_Score=259, Evalue=6e-71,
Organism=Escherichia coli, GI87082027, Length=150, Percent_Identity=30, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 20710; Mature: 20579

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPAIFIDRDGVINVDRGYVHKRDDFEYIDGVFDAVKICKDMGYLLVLVTNQSGIARGI
CCCCCEEEECCCEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECC
FTEEQFETLTEWMDWNFAEHDIDFDGIYYCPHHPEATVEQYKEECDCRKPNPGMFMSAQS
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECHH
FLDIDMEKSVMIGDKKEDMMAAQVAGVGTRILVRTGKPVTEEGEALATTVLDSIADVPKF
HCCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LFA
HCC
>Mature Secondary Structure 
SKPAIFIDRDGVINVDRGYVHKRDDFEYIDGVFDAVKICKDMGYLLVLVTNQSGIARGI
CCCCEEEECCCEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECC
FTEEQFETLTEWMDWNFAEHDIDFDGIYYCPHHPEATVEQYKEECDCRKPNPGMFMSAQS
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECHH
FLDIDMEKSVMIGDKKEDMMAAQVAGVGTRILVRTGKPVTEEGEALATTVLDSIADVPKF
HCCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LFA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]