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The map label for this gene is pheS [H]

Identifier: 209554440

GI number: 209554440

Start: 554636

End: 555637

Strand: Reverse

Name: pheS [H]

Synonym: UUR10_0502

Alternate gene names: 209554440

Gene position: 555637-554636 (Counterclockwise)

Preceding gene: 209554194

Following gene: 209554347

Centisome position: 63.54

GC content: 27.05

Gene sequence:

>1002_bases
ATGGATATTGCTAATCTAATTCAAAATTTAAAACAAACCTTACAAAATGCAAGTAATGAACGTCATTTGATTGAACTAAA
AAATATTTTTGTAAAACAACATTTATTACCACTATATGATGAACTAAAAAAAAGTGATAACAAAAAAGAAATGGGTTTGT
TAATTAATGAATTTAAGCAACAAATTGAATTAATTACAAACCAAGCTTTAGTGGAATTAAACAATAAAAGCGATCAAATT
GATTTAAAAAAATGAGCAAATAAAACTTTATTTACTCCCTTTATTAAAAATGGGCATCATCACATTATTAATAACATTAT
TGATGATATTGCCCAATTTTTTAAAAAACTAAACTTTGAGATTGTAAGTGGCCCAGAAGTTGTTTCACCAGTTTATAATT
TTGATCATTTAAATATTGATGAAAATCACCCAGCAAGAGCAACTGCTGATTCTTTTTTTATTAATTCTGTACAAATGTTA
CGTACTCATTGTACAACCACAACTGCTCAAGTTTTAGAAAACAATCCTCACAAAGACATTCGCATTATGTCTTTTGGTAA
TGTTTATCGAAAAGATGATGATGATGCAACTCATAGTCATCAATTTAACCAAGTTGATTTTGTATGAGTTAAAGAAGGTT
TAACCGTTGCTAATTTAAAATGATTAATTGATAGTTTAATTAAATATTTATTTGGTCAGAATTTAAAAACACGCTATCGC
TTAAGTTTTTTTCCATTTACTGAACCTTCGTTTGAGGTTGATGTTCAATGTTTTAAATGCGATTTAAAAGGATGTGCTGT
TTGTAAAAAAAGCACATGAATTGAAATCATGGGAACAGGGATGTTACATGAAAACGTTTTAAAAGCTGCTAATATTAATG
ATATTAAAACAGGAATGGCTTTTGGTGTGGGTATTGATCGGATTGCTATGTTAAAGTATGAAATTGATGATATTCGTTAT
TTATATTCAAACAACTTTAAATTTAATGCCCAAATTAAATAA

Upstream 100 bases:

>100_bases
AGTTAAAAACTGGTTCCGTAATTTTCAAAAAAATAATAAAGTTCAAAAAACAGATAAACAAGAACAAGAAGATCTTAAAA
AAGAAAGCGAGTAAATATTT

Downstream 100 bases:

>100_bases
ATTCCTAAATTCAATGAAAGAGTAAAAAAAAGATGATTTTAAGTTTAAATTTATTGCATAAGATTAGTCCAAAACTAAAA
AAGATTTCTTTAAATGAATT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDIANLIQNLKQTLQNASNERHLIELKNIFVKQHLLPLYDELKKSDNKKEMGLLINEFKQQIELITNQALVELNNKSDQI
DLKKWANKTLFTPFIKNGHHHIINNIIDDIAQFFKKLNFEIVSGPEVVSPVYNFDHLNIDENHPARATADSFFINSVQML
RTHCTTTTAQVLENNPHKDIRIMSFGNVYRKDDDDATHSHQFNQVDFVWVKEGLTVANLKWLIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKSTWIEIMGTGMLHENVLKAANINDIKTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK

Sequences:

>Translated_333_residues
MDIANLIQNLKQTLQNASNERHLIELKNIFVKQHLLPLYDELKKSDNKKEMGLLINEFKQQIELITNQALVELNNKSDQI
DLKK*ANKTLFTPFIKNGHHHIINNIIDDIAQFFKKLNFEIVSGPEVVSPVYNFDHLNIDENHPARATADSFFINSVQML
RTHCTTTTAQVLENNPHKDIRIMSFGNVYRKDDDDATHSHQFNQVDFV*VKEGLTVANLK*LIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKST*IEIMGTGMLHENVLKAANINDIKTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK
>Mature_333_residues
MDIANLIQNLKQTLQNASNERHLIELKNIFVKQHLLPLYDELKKSDNKKEMGLLINEFKQQIELITNQALVELNNKSDQI
DLKK*ANKTLFTPFIKNGHHHIINNIIDDIAQFFKKLNFEIVSGPEVVSPVYNFDHLNIDENHPARATADSFFINSVQML
RTHCTTTTAQVLENNPHKDIRIMSFGNVYRKDDDDATHSHQFNQVDFV*VKEGLTVANLK*LIDSLIKYLFGQNLKTRYR
LSFFPFTEPSFEVDVQCFKCDLKGCAVCKKST*IEIMGTGMLHENVLKAANINDIKTGMAFGVGIDRIAMLKYEIDDIRY
LYSNNFKFNAQIK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=310, Percent_Identity=27.0967741935484, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI4758340, Length=280, Percent_Identity=25.7142857142857, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1788007, Length=336, Percent_Identity=32.1428571428571, Blast_Score=181, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI32566635, Length=274, Percent_Identity=27.007299270073, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325304, Length=166, Percent_Identity=31.9277108433735, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137424, Length=252, Percent_Identity=28.1746031746032, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR022911
- InterPro:   IPR002319 [H]

Pfam domain/function: PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37789; Mature: 37789

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIANLIQNLKQTLQNASNERHLIELKNIFVKQHLLPLYDELKKSDNKKEMGLLINEFKQ
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QIELITNQALVELNNKSDQIDLKKANKTLFTPFIKNGHHHIINNIIDDIAQFFKKLNFEI
HHHHHHHHHHEEECCCCCEEEHHHCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VSGPEVVSPVYNFDHLNIDENHPARATADSFFINSVQMLRTHCTTTTAQVLENNPHKDIR
ECCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IMSFGNVYRKDDDDATHSHQFNQVDFVVKEGLTVANLKLIDSLIKYLFGQNLKTRYRLSF
EEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
FPFTEPSFEVDVQCFKCDLKGCAVCKKSTIEIMGTGMLHENVLKAANINDIKTGMAFGVG
ECCCCCCCEEEEEEEEECCCHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCC
IDRIAMLKYEIDDIRYLYSNNFKFNAQIK
HHHHEEEEEEHHHHHEEECCCEEEEEEEC
>Mature Secondary Structure
MDIANLIQNLKQTLQNASNERHLIELKNIFVKQHLLPLYDELKKSDNKKEMGLLINEFKQ
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QIELITNQALVELNNKSDQIDLKKANKTLFTPFIKNGHHHIINNIIDDIAQFFKKLNFEI
HHHHHHHHHHEEECCCCCEEEHHHCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VSGPEVVSPVYNFDHLNIDENHPARATADSFFINSVQMLRTHCTTTTAQVLENNPHKDIR
ECCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IMSFGNVYRKDDDDATHSHQFNQVDFVVKEGLTVANLKLIDSLIKYLFGQNLKTRYRLSF
EEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
FPFTEPSFEVDVQCFKCDLKGCAVCKKSTIEIMGTGMLHENVLKAANINDIKTGMAFGVG
ECCCCCCCEEEEEEEEECCCHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCC
IDRIAMLKYEIDDIRYLYSNNFKFNAQIK
HHHHEEEEEEHHHHHEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA