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The map label for this gene is grpE [H]

Identifier: 209554195

GI number: 209554195

Start: 500308

End: 500964

Strand: Reverse

Name: grpE [H]

Synonym: UUR10_0450

Alternate gene names: 209554195

Gene position: 500964-500308 (Counterclockwise)

Preceding gene: 209554560

Following gene: 209554408

Centisome position: 57.29

GC content: 24.05

Gene sequence:

>657_bases
ATGAGTAAAAATAATGAAAATATCAAACACCAAAATGAAGGCAAACTTCATGACCAAGTTGATAAAAAAGAAACTAAAAA
TCATGCTAAACAAGAATTTAAATACAAAGAATTGTATGAACATGAACTAAAAAAGAATAAGGAATTACAAAACGTTAATG
AATTATTAATAAACAAAAATCAACAATTAGAAATACAAATTAATCAATTAAATCAAGATTTTGTTAAACAATTAGAAACT
AAAACAAAACAAGCTCAAGAAATTTTAGAGCAAAAAGTTAATGAACTTGAAGCTCGTCATGAAACAAAAGTAAATGATGC
TGTTTTTAAAATCTTTAAATTTAAAATGGAACCATTATTAGATGCAATTAATCATTTTACAAAGATTGTTAACCAAAACT
ATGATGATCCTAAAATTCAAGCTTTTATCGAAGGTTTTAAAATGTTCTCTCAAAACATGATTGATGGTTTAGAAAATTTA
AAAATCACAAAAATATCACCCCAAATTAATGACATGTTAAATGATGATACAATGGAAGTTTTTGAAGTTGTTCAAAATAC
TAATAAACCTTCAATGCATGTTACTGAAGTCATAAGTGATGGTTTTAAATATAATGATAAAGTCATTAAATTCGCAGTTG
TTAAAGTTGCTAAATAA

Upstream 100 bases:

>100_bases
TAACTAAAGAAGAAATTGCTTATTTAAAAAATATTAGTGCTCGTACCAACCAAAGTGTTGAGTATTATAAAAATAAATTA
TTAAAAGAGGTTAATAAATA

Downstream 100 bases:

>100_bases
TTAAAAGTGATAAGTGGTTAACACCTATCACTTTTTTATTGCTTGTGTGTTAAAAAATTATTAATTGAAGATAATTAATT
ACATTTAATTAATTAAAATT

Product: co-chaperone GrpE

Products: NA

Alternate protein names: HSP-70 cofactor [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSKNNENIKHQNEGKLHDQVDKKETKNHAKQEFKYKELYEHELKKNKELQNVNELLINKNQQLEIQINQLNQDFVKQLET
KTKQAQEILEQKVNELEARHETKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLENL
KITKISPQINDMLNDDTMEVFEVVQNTNKPSMHVTEVISDGFKYNDKVIKFAVVKVAK

Sequences:

>Translated_218_residues
MSKNNENIKHQNEGKLHDQVDKKETKNHAKQEFKYKELYEHELKKNKELQNVNELLINKNQQLEIQINQLNQDFVKQLET
KTKQAQEILEQKVNELEARHETKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLENL
KITKISPQINDMLNDDTMEVFEVVQNTNKPSMHVTEVISDGFKYNDKVIKFAVVKVAK
>Mature_217_residues
SKNNENIKHQNEGKLHDQVDKKETKNHAKQEFKYKELYEHELKKNKELQNVNELLINKNQQLEIQINQLNQDFVKQLETK
TKQAQEILEQKVNELEARHETKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLENLK
ITKISPQINDMLNDDTMEVFEVVQNTNKPSMHVTEVISDGFKYNDKVIKFAVVKVAK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK and grpE. It is the nucleotide exchange factor for dnaK and may function as a thermosensor. Unfolded

COG id: COG0576

COG function: function code O; Molecular chaperone GrpE (heat shock protein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000740
- InterPro:   IPR009012 [H]

Pfam domain/function: PF01025 GrpE [H]

EC number: NA

Molecular weight: Translated: 25693; Mature: 25561

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNNENIKHQNEGKLHDQVDKKETKNHAKQEFKYKELYEHELKKNKELQNVNELLINKN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
QQLEIQINQLNQDFVKQLETKTKQAQEILEQKVNELEARHETKVNDAVFKIFKFKMEPLL
CEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLENLKITKISPQINDMLNDDTMEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHCCCHHHHH
FEVVQNTNKPSMHVTEVISDGFKYNDKVIKFAVVKVAK
HHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SKNNENIKHQNEGKLHDQVDKKETKNHAKQEFKYKELYEHELKKNKELQNVNELLINKN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
QQLEIQINQLNQDFVKQLETKTKQAQEILEQKVNELEARHETKVNDAVFKIFKFKMEPLL
CEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLENLKITKISPQINDMLNDDTMEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHCCCHHHHH
FEVVQNTNKPSMHVTEVISDGFKYNDKVIKFAVVKVAK
HHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA