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The map label for this gene is lldR [H]

Identifier: 209551920

GI number: 209551920

Start: 4518490

End: 4519167

Strand: Reverse

Name: lldR [H]

Synonym: Rleg2_4353

Alternate gene names: 209551920

Gene position: 4519167-4518490 (Counterclockwise)

Preceding gene: 209551922

Following gene: 209551919

Centisome position: 99.59

GC content: 66.37

Gene sequence:

>678_bases
ATGCGCGCAATCAGCAGGACCAATCTCGCCGATGAGGCCATCGAGGCGATCCGCAGCGATATCCTCGGCAAACGCTGGGC
GGTCGGGGAAAAATTGCCGAACGAGGCCTCGCTGTCGGCCATGCTCTCGGTGAGCCGCGGCACGGTGCGCGAGGCGGTGC
GGGTTCTCGTCTCCCAGGGTTATCTCGAAACCCGGCAGGGTTCGGGAACCTATGTGCGCGCGACCAGCGATGCCGGCCGG
CCGCTGACCATGGCCCGGCGCGCCAGCCTGCGCGACCAGTTCGAGGCGCGCCTGGCGCTCGACGTCGAGGCGGCCCGGCT
GACGGCGATCCGCAAGAGCCCGGAGACGGTGGCCGGGCTTCGCCGACTGCTTGCCGAACGCGGCAGTTACGACGGCGGCG
ATCAGGCTGCCTTTATCGAACGCGACCTTGCCTTCCACAAGGCCGTCATCGCCGCTTCCGGCAATCGGGCGATGATCGAG
ATCTACGATTTCTTCTCGGCCTCGATCGCCGACACCATCGCGGCGACGCTCGGCAAGGATATTCCCGAACCGGATATGCA
GGCGCATGCCGATATTGTCGACGCCATCGAAACCGGCGATCCCGACCAAGCGGATGCGGCGGTGCGCCGCTTCATGGCGC
CGCTTCTTGCCGTCCTCGACCGGATGATCCTGTCATGA

Upstream 100 bases:

>100_bases
CCGAGGCGGCCCTTTTTTATTGCCTTGATTTCAGGACCGTTGACGGATCATCGAAATCGCACTACTCATAAAGTCATCTG
ATGACTTTATGAGTAGTGCG

Downstream 100 bases:

>100_bases
ACACGCCTTCCAACGACCTCGCCGCCACGCTCGACCCATCCGACGAACTGCTTGTAGATGCCGAGGCCGGCAGCCTGCCG
CCGCCGCAGGCAACACCGGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRAISRTNLADEAIEAIRSDILGKRWAVGEKLPNEASLSAMLSVSRGTVREAVRVLVSQGYLETRQGSGTYVRATSDAGR
PLTMARRASLRDQFEARLALDVEAARLTAIRKSPETVAGLRRLLAERGSYDGGDQAAFIERDLAFHKAVIAASGNRAMIE
IYDFFSASIADTIAATLGKDIPEPDMQAHADIVDAIETGDPDQADAAVRRFMAPLLAVLDRMILS

Sequences:

>Translated_225_residues
MRAISRTNLADEAIEAIRSDILGKRWAVGEKLPNEASLSAMLSVSRGTVREAVRVLVSQGYLETRQGSGTYVRATSDAGR
PLTMARRASLRDQFEARLALDVEAARLTAIRKSPETVAGLRRLLAERGSYDGGDQAAFIERDLAFHKAVIAASGNRAMIE
IYDFFSASIADTIAATLGKDIPEPDMQAHADIVDAIETGDPDQADAAVRRFMAPLLAVLDRMILS
>Mature_225_residues
MRAISRTNLADEAIEAIRSDILGKRWAVGEKLPNEASLSAMLSVSRGTVREAVRVLVSQGYLETRQGSGTYVRATSDAGR
PLTMARRASLRDQFEARLALDVEAARLTAIRKSPETVAGLRRLLAERGSYDGGDQAAFIERDLAFHKAVIAASGNRAMIE
IYDFFSASIADTIAATLGKDIPEPDMQAHADIVDAIETGDPDQADAAVRRFMAPLLAVLDRMILS

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=221, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=27.9475982532751, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786303, Length=232, Percent_Identity=28.448275862069, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24360; Mature: 24360

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAISRTNLADEAIEAIRSDILGKRWAVGEKLPNEASLSAMLSVSRGTVREAVRVLVSQG
CCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YLETRQGSGTYVRATSDAGRPLTMARRASLRDQFEARLALDVEAARLTAIRKSPETVAGL
CHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RRLLAERGSYDGGDQAAFIERDLAFHKAVIAASGNRAMIEIYDFFSASIADTIAATLGKD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCC
IPEPDMQAHADIVDAIETGDPDQADAAVRRFMAPLLAVLDRMILS
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAISRTNLADEAIEAIRSDILGKRWAVGEKLPNEASLSAMLSVSRGTVREAVRVLVSQG
CCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YLETRQGSGTYVRATSDAGRPLTMARRASLRDQFEARLALDVEAARLTAIRKSPETVAGL
CHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RRLLAERGSYDGGDQAAFIERDLAFHKAVIAASGNRAMIEIYDFFSASIADTIAATLGKD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCC
IPEPDMQAHADIVDAIETGDPDQADAAVRRFMAPLLAVLDRMILS
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]