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The map label for this gene is yliJ [C]

Identifier: 209551856

GI number: 209551856

Start: 4459783

End: 4460463

Strand: Reverse

Name: yliJ [C]

Synonym: Rleg2_4288

Alternate gene names: 209551856

Gene position: 4460463-4459783 (Counterclockwise)

Preceding gene: 209551858

Following gene: 209551855

Centisome position: 98.29

GC content: 61.23

Gene sequence:

>681_bases
ATGAGCAAGCTTACCCTTATCAGTCATCATCTCTGCCCCTATGTGCAGCGCGCCGCGATCGCGCTTCTCGAAAAGGGCGT
GCCGTTTGAGCGCATCAACATCGATCTTGCCAACAAGCCGGATTGGTTTTTGAAGATTTCGCCGCTCGGCAAGGTGCCGC
TGCTGCGGATCGAGGCGGAGGATGGCAGCGAAGCCGTTCTGTTCGAAAGCAGCGTGATCTGCGAATATCTGGAGGAAACG
CAAGCCGGTGCCCTGCATCCCGCCGATCCGCTGACCCGCGCCCGTCATCGCGGCTGGATGGAATTCGGCTCCTCGGTGCT
TTCCGATCTCTGGGGCTATGAAACGGCGCAGGATGAATTACAGCTGGACGCCAAGCGCAAAGCGCTGACTGCCAAATTTG
CGACGCTCGAAGGGGCGCTGGGCGACGGCCCCTATTTTGCCGGCAGCAGCTTCAGCCTGGTCGATGCCGTTTTCGCGCCG
GTCTTCCGCTATTTCGATCTCTTCGATACGCTCGGCGACAGCGGCATCTTCGACGGGCTTGAGCGAACACAACGCTGGCG
CAAGGCACTGTCTGAGCGTGCGAGCGTCCGGGCGGCCGTCGGCGCGGATTACCCGCAGCGGCTGCTGGAATTCCTCGAGA
AACACTCCTCGATCCTGCTCAGGCAAGCTGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
TTTCGGCGTTTTTTCGGACATAAATGCAGTTACATCTATCTTGAATTCCGCCGCAAGCGATATTAGATGCATCTGCATAG
ATTGTGACCAGGAGATTTCC

Downstream 100 bases:

>100_bases
AGCGCGCCCAAGCGGCCGGACCTCCATCCGGCCGCCGGCAATTCGGCGACACAACGCTTCATTTTCGCCGCAAACGGGTC
TAAGTCTGCCAGCCTCAAAG

Product: glutathione S-transferase domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSKLTLISHHLCPYVQRAAIALLEKGVPFERINIDLANKPDWFLKISPLGKVPLLRIEAEDGSEAVLFESSVICEYLEET
QAGALHPADPLTRARHRGWMEFGSSVLSDLWGYETAQDELQLDAKRKALTAKFATLEGALGDGPYFAGSSFSLVDAVFAP
VFRYFDLFDTLGDSGIFDGLERTQRWRKALSERASVRAAVGADYPQRLLEFLEKHSSILLRQAAAA

Sequences:

>Translated_226_residues
MSKLTLISHHLCPYVQRAAIALLEKGVPFERINIDLANKPDWFLKISPLGKVPLLRIEAEDGSEAVLFESSVICEYLEET
QAGALHPADPLTRARHRGWMEFGSSVLSDLWGYETAQDELQLDAKRKALTAKFATLEGALGDGPYFAGSSFSLVDAVFAP
VFRYFDLFDTLGDSGIFDGLERTQRWRKALSERASVRAAVGADYPQRLLEFLEKHSSILLRQAAAA
>Mature_225_residues
SKLTLISHHLCPYVQRAAIALLEKGVPFERINIDLANKPDWFLKISPLGKVPLLRIEAEDGSEAVLFESSVICEYLEETQ
AGALHPADPLTRARHRGWMEFGSSVLSDLWGYETAQDELQLDAKRKALTAKFATLEGALGDGPYFAGSSFSLVDAVFAPV
FRYFDLFDTLGDSGIFDGLERTQRWRKALSERASVRAAVGADYPQRLLEFLEKHSSILLRQAAAA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4758484, Length=203, Percent_Identity=29.064039408867, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI300360534, Length=197, Percent_Identity=29.4416243654822, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI300360532, Length=201, Percent_Identity=28.8557213930348, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI38016131, Length=197, Percent_Identity=29.4416243654822, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI300360569, Length=200, Percent_Identity=29.5, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI300360567, Length=199, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI300360571, Length=192, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI87081789, Length=217, Percent_Identity=30.8755760368664, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1789624, Length=162, Percent_Identity=31.4814814814815, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790018, Length=148, Percent_Identity=33.1081081081081, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193207701, Length=205, Percent_Identity=29.7560975609756, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144449, Length=117, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21355763, Length=215, Percent_Identity=30.2325581395349, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355779, Length=165, Percent_Identity=36.3636363636364, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355775, Length=105, Percent_Identity=41.9047619047619, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24660979, Length=200, Percent_Identity=28.5, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355765, Length=105, Percent_Identity=39.0476190476191, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 25089; Mature: 24958

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTLISHHLCPYVQRAAIALLEKGVPFERINIDLANKPDWFLKISPLGKVPLLRIEAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECC
DGSEAVLFESSVICEYLEETQAGALHPADPLTRARHRGWMEFGSSVLSDLWGYETAQDEL
CCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QLDAKRKALTAKFATLEGALGDGPYFAGSSFSLVDAVFAPVFRYFDLFDTLGDSGIFDGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERTQRWRKALSERASVRAAVGADYPQRLLEFLEKHSSILLRQAAAA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLTLISHHLCPYVQRAAIALLEKGVPFERINIDLANKPDWFLKISPLGKVPLLRIEAE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECC
DGSEAVLFESSVICEYLEETQAGALHPADPLTRARHRGWMEFGSSVLSDLWGYETAQDEL
CCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QLDAKRKALTAKFATLEGALGDGPYFAGSSFSLVDAVFAPVFRYFDLFDTLGDSGIFDGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERTQRWRKALSERASVRAAVGADYPQRLLEFLEKHSSILLRQAAAA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11900268 [H]