Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 209551648

GI number: 209551648

Start: 4252561

End: 4254441

Strand: Reverse

Name: dnaX [H]

Synonym: Rleg2_4077

Alternate gene names: 209551648

Gene position: 4254441-4252561 (Counterclockwise)

Preceding gene: 209551654

Following gene: 209551647

Centisome position: 93.75

GC content: 65.39

Gene sequence:

>1881_bases
ATGAGCGACACCGAGCGACAATCAAAAGATGCCGCCTCGACGGGCACCGGGTACCGGGTGCTGGCTCGCAAATACCGCCC
CAAGGATTTCACGGACCTGATGGTCGGCCAGGAGCCGATGGTCCGCACGCTGACCAACGCCTTCGAAACCGGCCGCATCG
CCCAGGCCTATATGCTGACCGGCGTGCGGGGCGTCGGCAAGACGACGACGGCGCGCATCCTGGCGCGGGCGCTGAATTAC
AAGACATCCGATGTCGACAAGCCGACGATCGACCTTCGCACGCCTGGCGAACACTGCCAGGCGATCATGGAAGGCCGGCA
TGTCGACGTGATCGAAATGGATGCCGCCTCCCATACCGGCATCGACGATATAAGAGAGATCATCGAGCAGGTGCGCTACC
GGCCGGTTTCGGCGCGCTACAAGGTCTATATCATCGACGAAGTGCACATGCTGTCGACGCAGGCCTTCAACGGCCTGTTG
AAGACGCTGGAAGAGCCGCCGGAGCATGTGAAGTTCATCTTCGCCACCACCGAAATCCGCAAAGTGCCGATCACCGTGCT
GTCGCGCTGCCAGCGTTTCGACCTGCGCCGCATCAGCGCGTCGGATCTCGTCGGGCTGTTTTCGACAATCGCCGCCAAGG
AAGGCATCGAGGCCGAACCGGACGCGCTGGCGATGATCGCACGTGCCGCCGAAGGCTCGGCGCGCGACGGGCTGTCGCTG
CTCGATCAGGCGATCGCCCATGGCGCAGGCGCCGTCCAGGCGGAAGCCGTGCGCGGAATGCTCGGCCTTGCCGACCGCGC
CCGGATCGTCGATCTCTTCCAGCATGTCGTCAAGGGTGACGTGGCAGCAGCCCTCGGCGAATTCCAGAGCCAGTACGAGG
CCGGCGCCAATCCGGTGGTGGTGCTGACCGATCTTGCCGATTTCACCCATTTGGTGACGCGGCTGAAATATGTGCCGGAT
GCGGCGAACGATCCCTCGCTCAGCGAAGTCGAGCGCACCAAGGCCGCGGAATTCGCCAAGGGCGTCGCCGTCACGACGCT
GTCGCGCATCTGGCAGATGCTGCTGAAGGGCATTCCGGAAACGGAAGGCTCGTCGCGGACGGCGGGTGCGGCCGAAATGG
TGCTGATCCGCCTCGCGCATGCCGCGCATCTGCCGGCGCCCGAGGATGCGGCGCGGCGGCTTGGCGAATTTTCCGGCGAC
AATGCCGGCCCGCGGCCCGCCTCCTCGCCATCAGGCAATGGCGGCGGCAGCGGCACGCGTGTTCCCTATCAAAGCAGTGT
CGCCGCACGCGCGCCGGAAATCGCACCCGGCAAGCCGCAGGCGTCCGCGCCGGTGGCGATGCTGCGCGCCGTGCCGAGCA
GCCAGCCCGAGACGCTGCCTGTCGGACGGATCGAGACGAAACCGGTCGAGACACCGAAGCCGCTCGTCCCGGTCAATTCG
GTCAGCGATATCGTCGAGCTCGCCGCCGAGAAGCGGGACGTCAAGCTGAAGGCGCTGGTGCGCAACTTCGTGCGCCCTGT
CCGCATCGAGCCCGGCCGGCTTGATGTGAACCTTACCGAGGGCGCACCAGGCACGCTGCTGAACGAGCTTGCCGTCAAGC
TCAAGGAATGGACGGGCATCCATTGGATCGTCAGCACCAGCCGCGAAGAAGGCGGGCCGACGATGGTCGAGGCGGAAGCC
AAGGCTCAGCAACAACGCGTCAGCGATGCACGCCAAGACCCTGATGTCGCGGCGATCCTTGCGCAGTTTCCGGGCGCCAA
GATCATCGACGTGCGCGTAAGGGCGCCGACGCCGGAGGAGGAAGCCGAAGAGGCGATCCCGCCTGCCGCCGCCGAATCGG
AAGATGGTGATATCCTGCCCGGCGACGACATAGAATTCTGA

Upstream 100 bases:

>100_bases
CCGGAAGGAAGCAGCCCTAACGAGCCCGGCACGGGTCATCGTGCCAGCCTCCCACCTTCTCTCCACGAAGTGCCCGACGA
TCCGGGCGACAAGCAGGGCG

Downstream 100 bases:

>100_bases
TTTCAAGAAGGAGCGAGACGATGCGCGACATCATGGGCATGATGGGCAAAGTCAAGGAAATGCAGGCCAAGATGGAGCAG
ATGCAGGCGGAGATCGCCGA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MSDTERQSKDAASTGTGYRVLARKYRPKDFTDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNY
KTSDVDKPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLL
KTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFSTIAAKEGIEAEPDALAMIARAAEGSARDGLSL
LDQAIAHGAGAVQAEAVRGMLGLADRARIVDLFQHVVKGDVAAALGEFQSQYEAGANPVVVLTDLADFTHLVTRLKYVPD
AANDPSLSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLGEFSGD
NAGPRPASSPSGNGGGSGTRVPYQSSVAARAPEIAPGKPQASAPVAMLRAVPSSQPETLPVGRIETKPVETPKPLVPVNS
VSDIVELAAEKRDVKLKALVRNFVRPVRIEPGRLDVNLTEGAPGTLLNELAVKLKEWTGIHWIVSTSREEGGPTMVEAEA
KAQQQRVSDARQDPDVAAILAQFPGAKIIDVRVRAPTPEEEAEEAIPPAAAESEDGDILPGDDIEF

Sequences:

>Translated_626_residues
MSDTERQSKDAASTGTGYRVLARKYRPKDFTDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNY
KTSDVDKPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLL
KTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFSTIAAKEGIEAEPDALAMIARAAEGSARDGLSL
LDQAIAHGAGAVQAEAVRGMLGLADRARIVDLFQHVVKGDVAAALGEFQSQYEAGANPVVVLTDLADFTHLVTRLKYVPD
AANDPSLSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLGEFSGD
NAGPRPASSPSGNGGGSGTRVPYQSSVAARAPEIAPGKPQASAPVAMLRAVPSSQPETLPVGRIETKPVETPKPLVPVNS
VSDIVELAAEKRDVKLKALVRNFVRPVRIEPGRLDVNLTEGAPGTLLNELAVKLKEWTGIHWIVSTSREEGGPTMVEAEA
KAQQQRVSDARQDPDVAAILAQFPGAKIIDVRVRAPTPEEEAEEAIPPAAAESEDGDILPGDDIEF
>Mature_625_residues
SDTERQSKDAASTGTGYRVLARKYRPKDFTDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYK
TSDVDKPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLK
TLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISASDLVGLFSTIAAKEGIEAEPDALAMIARAAEGSARDGLSLL
DQAIAHGAGAVQAEAVRGMLGLADRARIVDLFQHVVKGDVAAALGEFQSQYEAGANPVVVLTDLADFTHLVTRLKYVPDA
ANDPSLSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPETEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLGEFSGDN
AGPRPASSPSGNGGGSGTRVPYQSSVAARAPEIAPGKPQASAPVAMLRAVPSSQPETLPVGRIETKPVETPKPLVPVNSV
SDIVELAAEKRDVKLKALVRNFVRPVRIEPGRLDVNLTEGAPGTLLNELAVKLKEWTGIHWIVSTSREEGGPTMVEAEAK
AQQQRVSDARQDPDVAAILAQFPGAKIIDVRVRAPTPEEEAEEAIPPAAAESEDGDILPGDDIEF

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=374, Percent_Identity=41.1764705882353, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=25.9414225941423, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322528, Length=319, Percent_Identity=21.0031347962382, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647857, Length=288, Percent_Identity=26.0416666666667, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 67369; Mature: 67238

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTERQSKDAASTGTGYRVLARKYRPKDFTDLMVGQEPMVRTLTNAFETGRIAQAYMLT
CCCCHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
GVRGVGKTTTARILARALNYKTSDVDKPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCC
IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR
HHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHH
KVPITVLSRCQRFDLRRISASDLVGLFSTIAAKEGIEAEPDALAMIARAAEGSARDGLSL
HCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHH
LDQAIAHGAGAVQAEAVRGMLGLADRARIVDLFQHVVKGDVAAALGEFQSQYEAGANPVV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLTDLADFTHLVTRLKYVPDAANDPSLSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPE
EEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
TEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLGEFSGDNAGPRPASSPSGNGGGSGTR
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
VPYQSSVAARAPEIAPGKPQASAPVAMLRAVPSSQPETLPVGRIETKPVETPKPLVPVNS
CCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
VSDIVELAAEKRDVKLKALVRNFVRPVRIEPGRLDVNLTEGAPGTLLNELAVKLKEWTGI
HHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCE
HWIVSTSREEGGPTMVEAEAKAQQQRVSDARQDPDVAAILAQFPGAKIIDVRVRAPTPEE
EEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCHH
EAEEAIPPAAAESEDGDILPGDDIEF
HHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDTERQSKDAASTGTGYRVLARKYRPKDFTDLMVGQEPMVRTLTNAFETGRIAQAYMLT
CCCHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
GVRGVGKTTTARILARALNYKTSDVDKPTIDLRTPGEHCQAIMEGRHVDVIEMDAASHTG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCC
IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR
HHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHH
KVPITVLSRCQRFDLRRISASDLVGLFSTIAAKEGIEAEPDALAMIARAAEGSARDGLSL
HCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHH
LDQAIAHGAGAVQAEAVRGMLGLADRARIVDLFQHVVKGDVAAALGEFQSQYEAGANPVV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLTDLADFTHLVTRLKYVPDAANDPSLSEVERTKAAEFAKGVAVTTLSRIWQMLLKGIPE
EEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
TEGSSRTAGAAEMVLIRLAHAAHLPAPEDAARRLGEFSGDNAGPRPASSPSGNGGGSGTR
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
VPYQSSVAARAPEIAPGKPQASAPVAMLRAVPSSQPETLPVGRIETKPVETPKPLVPVNS
CCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
VSDIVELAAEKRDVKLKALVRNFVRPVRIEPGRLDVNLTEGAPGTLLNELAVKLKEWTGI
HHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCE
HWIVSTSREEGGPTMVEAEAKAQQQRVSDARQDPDVAAILAQFPGAKIIDVRVRAPTPEE
EEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCHH
EAEEAIPPAAAESEDGDILPGDDIEF
HHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]