Click here to switch to the map view.

The map label for this gene is uxaC [H]

Identifier: 209551594

GI number: 209551594

Start: 4195646

End: 4197061

Strand: Reverse

Name: uxaC [H]

Synonym: Rleg2_4023

Alternate gene names: 209551594

Gene position: 4197061-4195646 (Counterclockwise)

Preceding gene: 209551596

Following gene: 209551593

Centisome position: 92.49

GC content: 66.03

Gene sequence:

>1416_bases
ATGGATGTAGGAAACGGCTTTCTTCATCCGGACCGGCTCTTTCCGGCCGACCCGGCAACGCGGACCATTGCGCGCGACCT
CTACGAGACGGTGCGCAATCTTCCGATCGTCAGCCCGCACGGGCATACCGAACCGTCCTGGTTCGCCGACGACAAGCCCT
TCGAAGACGCGGCCTCGCTGCTGGTCATTCCCGATCACTATCTCTTCCGCATGCTGCACAGCGTCGGCGTCGCCCTGGAC
GAACTCGGCGTTCCCAGGCTCGACGGCAAGCCGGTGGCCGAGGGACGGGCGATCTGGCGGACCCTTGCCAGGCATTACCA
TCTCTTCCGCGGAACGCCGTCGAGCCTCTGGGTCGACCACGCGATGTCGGCCGTGCTCGGCTGCACCGAGCCGCTGACAT
CCGACAATGCCGATGCGCTCTATGACCATATCAATGCCCAGCTTGCCCTTCCCGAATTCCGTCCGCGGGCGCTGCATCAG
CGATTCGGCATCGAAACGATCGCGACGACGGAGGGCGCGCTCGACCCGCTGGCCCATCACCAGAAGATGGCCGCCGACGG
CTGGATCGGCAAGGTCCGCACCACCTACCGGCCGGACAGCGTCACCGATCCCGACGCCATCGGCTTCCGCGACAATCTCG
TCAAGTTCGGAGAGATCACCGGCGCCGATGTGACGCGCTGGGACGGGCTGATCGAGGCGCATCGGCGCCGGCGCGCCTAT
TTCCGCCAGTTCGGCGCCACCGCGACCGATCACGGCGTGCCCACCGCCTTCACGGCCGACCTGCCGCTTGCGGAAAAGCA
GGCGCTGCTCGACAAGGCGCTGAAGGGGCCGCTTTCGCGTGAAGAGGCGGAACTCTTCCGCGGCCAGATGATGACCGAGA
TGGCCGGGCTTTCGGCCGAAGACGGCATGGTCATGCAGATCCACGCCGGCTCGCGGCGCAATACCGACAGCGGGCTCTTT
GCGACGCGCGGCCCGAATATGGGCGCCGATATCCCGACGCGCACCGACTGGGTCGGTGGGCTCAATGCGCTGCTTTCCAG
ATACGGCCATGCGCCGGGGCTGCGGGTGCTGCTCTTCACCCTCGACGAGACGACCTATGCGCGCGAGATGGCGCCGATGG
TCGGCCATTGGCCCTGCCTGATGATCGGCCCGCCCTGGTGGTTCCACGACAGCCCGCTCGGCATTCGCCGCTATCTCGAC
CAGGTGGTGGAAACGGCAGGCTTTGCCAATATGGCCGGCTTCAACGACGATACGCGGGCGCTGCTTTCGATCCCGGCTCG
GCATGACGTCTGGCGCCGCGAAGTCTGCCGCTTCCTCGCCGGGCTCGCCGCCGAGCACCGGATTTCCAAGAAGGAAGCCG
AGATCGTGGCGGGCGAACTCTCCTATGGCAATGCGAAGAAGGCCTACAAGCTGTGA

Upstream 100 bases:

>100_bases
TGGCGCGACCATGCGCAAAAACCGAACCATCTGGTTACTAAAAGACCTTGCCGCGCCTGATGTTGTGGGGTAGGCCCTTA
TCCATCAGGGAGGAATACTG

Downstream 100 bases:

>100_bases
GCGAACGACTGCAGACCCTTTCCGGCCTCGCCCCGACGGCGAAGCTTCCCGCCTATGATCGCAGCCGGCTGAAAAGCGGC
ATCCTGCATCTGGGGCCCGG

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MDVGNGFLHPDRLFPADPATRTIARDLYETVRNLPIVSPHGHTEPSWFADDKPFEDAASLLVIPDHYLFRMLHSVGVALD
ELGVPRLDGKPVAEGRAIWRTLARHYHLFRGTPSSLWVDHAMSAVLGCTEPLTSDNADALYDHINAQLALPEFRPRALHQ
RFGIETIATTEGALDPLAHHQKMAADGWIGKVRTTYRPDSVTDPDAIGFRDNLVKFGEITGADVTRWDGLIEAHRRRRAY
FRQFGATATDHGVPTAFTADLPLAEKQALLDKALKGPLSREEAELFRGQMMTEMAGLSAEDGMVMQIHAGSRRNTDSGLF
ATRGPNMGADIPTRTDWVGGLNALLSRYGHAPGLRVLLFTLDETTYAREMAPMVGHWPCLMIGPPWWFHDSPLGIRRYLD
QVVETAGFANMAGFNDDTRALLSIPARHDVWRREVCRFLAGLAAEHRISKKEAEIVAGELSYGNAKKAYKL

Sequences:

>Translated_471_residues
MDVGNGFLHPDRLFPADPATRTIARDLYETVRNLPIVSPHGHTEPSWFADDKPFEDAASLLVIPDHYLFRMLHSVGVALD
ELGVPRLDGKPVAEGRAIWRTLARHYHLFRGTPSSLWVDHAMSAVLGCTEPLTSDNADALYDHINAQLALPEFRPRALHQ
RFGIETIATTEGALDPLAHHQKMAADGWIGKVRTTYRPDSVTDPDAIGFRDNLVKFGEITGADVTRWDGLIEAHRRRRAY
FRQFGATATDHGVPTAFTADLPLAEKQALLDKALKGPLSREEAELFRGQMMTEMAGLSAEDGMVMQIHAGSRRNTDSGLF
ATRGPNMGADIPTRTDWVGGLNALLSRYGHAPGLRVLLFTLDETTYAREMAPMVGHWPCLMIGPPWWFHDSPLGIRRYLD
QVVETAGFANMAGFNDDTRALLSIPARHDVWRREVCRFLAGLAAEHRISKKEAEIVAGELSYGNAKKAYKL
>Mature_471_residues
MDVGNGFLHPDRLFPADPATRTIARDLYETVRNLPIVSPHGHTEPSWFADDKPFEDAASLLVIPDHYLFRMLHSVGVALD
ELGVPRLDGKPVAEGRAIWRTLARHYHLFRGTPSSLWVDHAMSAVLGCTEPLTSDNADALYDHINAQLALPEFRPRALHQ
RFGIETIATTEGALDPLAHHQKMAADGWIGKVRTTYRPDSVTDPDAIGFRDNLVKFGEITGADVTRWDGLIEAHRRRRAY
FRQFGATATDHGVPTAFTADLPLAEKQALLDKALKGPLSREEAELFRGQMMTEMAGLSAEDGMVMQIHAGSRRNTDSGLF
ATRGPNMGADIPTRTDWVGGLNALLSRYGHAPGLRVLLFTLDETTYAREMAPMVGHWPCLMIGPPWWFHDSPLGIRRYLD
QVVETAGFANMAGFNDDTRALLSIPARHDVWRREVCRFLAGLAAEHRISKKEAEIVAGELSYGNAKKAYKL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=430, Percent_Identity=26.9767441860465, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 52314; Mature: 52314

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGNGFLHPDRLFPADPATRTIARDLYETVRNLPIVSPHGHTEPSWFADDKPFEDAASL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHCCCCE
LVIPDHYLFRMLHSVGVALDELGVPRLDGKPVAEGRAIWRTLARHYHLFRGTPSSLWVDH
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AMSAVLGCTEPLTSDNADALYDHINAQLALPEFRPRALHQRFGIETIATTEGALDPLAHH
HHHHHHHCCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEECCCCCHHHHHHH
QKMAADGWIGKVRTTYRPDSVTDPDAIGFRDNLVKFGEITGADVTRWDGLIEAHRRRRAY
HHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FRQFGATATDHGVPTAFTADLPLAEKQALLDKALKGPLSREEAELFRGQMMTEMAGLSAE
HHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
DGMVMQIHAGSRRNTDSGLFATRGPNMGADIPTRTDWVGGLNALLSRYGHAPGLRVLLFT
CCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
LDETTYAREMAPMVGHWPCLMIGPPWWFHDSPLGIRRYLDQVVETAGFANMAGFNDDTRA
ECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHH
LLSIPARHDVWRREVCRFLAGLAAEHRISKKEAEIVAGELSYGNAKKAYKL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDVGNGFLHPDRLFPADPATRTIARDLYETVRNLPIVSPHGHTEPSWFADDKPFEDAASL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHCCCCE
LVIPDHYLFRMLHSVGVALDELGVPRLDGKPVAEGRAIWRTLARHYHLFRGTPSSLWVDH
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AMSAVLGCTEPLTSDNADALYDHINAQLALPEFRPRALHQRFGIETIATTEGALDPLAHH
HHHHHHHCCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEECCCCCHHHHHHH
QKMAADGWIGKVRTTYRPDSVTDPDAIGFRDNLVKFGEITGADVTRWDGLIEAHRRRRAY
HHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FRQFGATATDHGVPTAFTADLPLAEKQALLDKALKGPLSREEAELFRGQMMTEMAGLSAE
HHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
DGMVMQIHAGSRRNTDSGLFATRGPNMGADIPTRTDWVGGLNALLSRYGHAPGLRVLLFT
CCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
LDETTYAREMAPMVGHWPCLMIGPPWWFHDSPLGIRRYLDQVVETAGFANMAGFNDDTRA
ECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHH
LLSIPARHDVWRREVCRFLAGLAAEHRISKKEAEIVAGELSYGNAKKAYKL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA