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The map label for this gene is ycgM [C]

Identifier: 209551520

GI number: 209551520

Start: 4097782

End: 4098624

Strand: Direct

Name: ycgM [C]

Synonym: Rleg2_3949

Alternate gene names: 209551520

Gene position: 4097782-4098624 (Clockwise)

Preceding gene: 209551517

Following gene: 209551521

Centisome position: 90.3

GC content: 59.79

Gene sequence:

>843_bases
ATGAAGCTGATGCGTGTTGGCCAAGCAGGCAATGAAAAACCCGCGCTTCTCGACGTCGATGGCAAGATCCGCGATCTCTC
CGGTCATGTGGCCGATATCGGCGGCGAGGTGATCACGCCGGCCGGTCTTGCAAAGATAGCGGCGATCGATCCGAAGAGCC
TTCCGGAACTTATGCCCGGCCGTATCGGCGCCTGCGTCGCCGGCACTGGCAAATTCATCTGCATCGGCTTGAATTATTCG
GATCATGCTGCCGAAACCGGCGCCACCGTTCCGCCCGAGCCGATCATCTTCATGAAAGCAACATCGGCAATTGTCGGCCC
GAACGACGATGTCATCATCCCCCGCGGTTCGGAAAAGACCGATTGGGAAGTCGAACTCGGCGTCGTCATCGGCAAGACTG
CCAAATATGTAACGGAAGCCGAAGCGCTGGACTATGTCGCCGGTTATTGCGTCTCCAACGATGTCTCCGAGCGCGCTTTC
CAGACCGAGCGGTCCGGGCAATGGACGAAGGGCAAGTCCTGCGACACTTTTGGCCCGATCGGCCCATGGCTCGTGACCAA
GGACGAAATTCCCGAACCGCAGAACCTTGGCATGTGGCTGACGGTCAACGGCCAGAAGATGCAGAACGGCTCGTCGAAGA
CGATGGTTTACGGCGTGGCTTTCCTGGTCTCCTACCTCAGCCAGTTCATGTCGCTGCATCCCGGCGACGTGATCTCGACC
GGCACGCCTCCGGGCGTCGGCATGGGCCTCAAGCCGCCGCGTTATCTCAAGGCTGGCGACGTGGTCGAACTCGGCATCGA
AGGTCTCGGCACCCAGAAGCAGACCTTCGTAGCGGACCGTTAA

Upstream 100 bases:

>100_bases
AGGAAAGCCGTACCGCTTCGCGCCAAAGCCGTAATGACACCGGTGAATAATTCGTTCATAGGTGGCTGCAAATCCGTTTT
TTTGATGAGGAGGAAATTCC

Downstream 100 bases:

>100_bases
CGACGCTTCCTGCTGAGAAACTTAAGTTTTCAGGGCGATTATGATGCCGGAGAGTCACTTCTCCGGCATTTCTTGTGCGG
GTCTGGTTCGTCCATGTTGC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLMRVGQAGNEKPALLDVDGKIRDLSGHVADIGGEVITPAGLAKIAAIDPKSLPELMPGRIGACVAGTGKFICIGLNYS
DHAAETGATVPPEPIIFMKATSAIVGPNDDVIIPRGSEKTDWEVELGVVIGKTAKYVTEAEALDYVAGYCVSNDVSERAF
QTERSGQWTKGKSCDTFGPIGPWLVTKDEIPEPQNLGMWLTVNGQKMQNGSSKTMVYGVAFLVSYLSQFMSLHPGDVIST
GTPPGVGMGLKPPRYLKAGDVVELGIEGLGTQKQTFVADR

Sequences:

>Translated_280_residues
MKLMRVGQAGNEKPALLDVDGKIRDLSGHVADIGGEVITPAGLAKIAAIDPKSLPELMPGRIGACVAGTGKFICIGLNYS
DHAAETGATVPPEPIIFMKATSAIVGPNDDVIIPRGSEKTDWEVELGVVIGKTAKYVTEAEALDYVAGYCVSNDVSERAF
QTERSGQWTKGKSCDTFGPIGPWLVTKDEIPEPQNLGMWLTVNGQKMQNGSSKTMVYGVAFLVSYLSQFMSLHPGDVIST
GTPPGVGMGLKPPRYLKAGDVVELGIEGLGTQKQTFVADR
>Mature_280_residues
MKLMRVGQAGNEKPALLDVDGKIRDLSGHVADIGGEVITPAGLAKIAAIDPKSLPELMPGRIGACVAGTGKFICIGLNYS
DHAAETGATVPPEPIIFMKATSAIVGPNDDVIIPRGSEKTDWEVELGVVIGKTAKYVTEAEALDYVAGYCVSNDVSERAF
QTERSGQWTKGKSCDTFGPIGPWLVTKDEIPEPQNLGMWLTVNGQKMQNGSSKTMVYGVAFLVSYLSQFMSLHPGDVIST
GTPPGVGMGLKPPRYLKAGDVVELGIEGLGTQKQTFVADR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=50.4807692307692, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI40786394, Length=208, Percent_Identity=50, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI215422413, Length=201, Percent_Identity=37.3134328358209, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI66348062, Length=201, Percent_Identity=37.3134328358209, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=37.3134328358209, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=34.8258706467662, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=36.6834170854271, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=32.5688073394495, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28572127, Length=210, Percent_Identity=48.5714285714286, Blast_Score=200, Evalue=7e-52,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=37.799043062201, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24663695, Length=225, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29666; Mature: 29666

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMRVGQAGNEKPALLDVDGKIRDLSGHVADIGGEVITPAGLAKIAAIDPKSLPELMPG
CCCEECCCCCCCCCEEEECCCCEEECCCCHHHCCCCEECCCCCEEEEECCCHHHHHHCCC
RIGACVAGTGKFICIGLNYSDHAAETGATVPPEPIIFMKATSAIVGPNDDVIIPRGSEKT
CCCEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCCC
DWEVELGVVIGKTAKYVTEAEALDYVAGYCVSNDVSERAFQTERSGQWTKGKSCDTFGPI
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GPWLVTKDEIPEPQNLGMWLTVNGQKMQNGSSKTMVYGVAFLVSYLSQFMSLHPGDVIST
CCEEEECCCCCCCCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
GTPPGVGMGLKPPRYLKAGDVVELGIEGLGTQKQTFVADR
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCC
>Mature Secondary Structure
MKLMRVGQAGNEKPALLDVDGKIRDLSGHVADIGGEVITPAGLAKIAAIDPKSLPELMPG
CCCEECCCCCCCCCEEEECCCCEEECCCCHHHCCCCEECCCCCEEEEECCCHHHHHHCCC
RIGACVAGTGKFICIGLNYSDHAAETGATVPPEPIIFMKATSAIVGPNDDVIIPRGSEKT
CCCEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCCC
DWEVELGVVIGKTAKYVTEAEALDYVAGYCVSNDVSERAFQTERSGQWTKGKSCDTFGPI
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GPWLVTKDEIPEPQNLGMWLTVNGQKMQNGSSKTMVYGVAFLVSYLSQFMSLHPGDVIST
CCEEEECCCCCCCCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
GTPPGVGMGLKPPRYLKAGDVVELGIEGLGTQKQTFVADR
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA