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The map label for this gene is metA [H]

Identifier: 209551376

GI number: 209551376

Start: 3936361

End: 3937284

Strand: Reverse

Name: metA [H]

Synonym: Rleg2_3805

Alternate gene names: 209551376

Gene position: 3937284-3936361 (Counterclockwise)

Preceding gene: 209551378

Following gene: 209551375

Centisome position: 86.76

GC content: 57.47

Gene sequence:

>924_bases
ATGCCCATCAAGATTCCTGACACGCTGCCCGCCTTTGAAACCCTCGTTCAAGAGGGTGTGCGGGTGATGACCGAGACGCT
GGCGATTCGTCAGGATATTCGTCCGCTGCAGATCGGACTGCTCAACTTGATGCCGAACAAGATCAAGACCGAATTGCAGA
TGGCCCGCCTTGTCGGCGCCTCGCCGCTGCAGGTCGAGCTGTCGCTGATCCGCATCGGCGGCCACAAGGCGAAGAACACC
TCCGAAGATCACCTGCTTGCCTTCTACCAGACCTGGGAGGAGGTGAAGCACCGCAAATTCGACGGCTTCATCATCACCGG
GGCGCCGATCGAGTTATTGCCCTACGAGGACGTGACCTATTGGCCGGAGATGCAGGAGATTCTCGACTGGACGGAAACGA
ATGTGCATTCGACGATGAACGTCTGCTGGGGCGCGATGGCGGCAATCTATCATTTCCACGGCGTGCCGAAATACGAGCTG
AAGGAGAAGGCTTTCGGCGTCTATCGCCACCGCAACCTGAAGCCCTCGTCCATCTATCTCAACGGCTTTTCCGACAATTT
CGAGGTGCCGGTGTCGCGCTGGACCGAGGTGCGCCGCGACGATATCGAGAAATCGGACGAGCTGGAGATCCTGATGGAAT
CCAGCGAGATGGGCGTCTGCCTCGTGCACGAGAAGCGCGGCCGTCGGCTCTATATGTTCAACCACGTCGAATATGATTCC
ACCTCGCTGTCCGACGAGTATTTCCGCGACGTCAATACCGGCGTGCCGATCAAGATGCCGCACAATTATTTCCCGCATAA
TGATCCGGCGCTTGCGCCGCAGAACCGCTGGCGCAGCCATGCGCATCTTTTGTTCGGCAACTGGATCAACGAGATCTACC
AGACGACGCCGTTTGATGTAGAGGAGATCGGAATGGATCTGTGA

Upstream 100 bases:

>100_bases
CGGCTTGCAGCCACGTTAAAAAATTCGCTAAAGGGCCGCGTGCGGACCGGTAGCGATTTTTTTCGCCGCCGGTTTTTTGC
TTTTTGATCGAGTGACCGCA

Downstream 100 bases:

>100_bases
GGGGCATCCCTTTCTGATCTCGGCCGGTTGCGGTTTGGAACAAATGCGGGCAGGTTCCGGTCGGAATGCTAGATATCAAA
CGGACGGTCGATCATGTCGG

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPIKIPDTLPAFETLVQEGVRVMTETLAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGASPLQVELSLIRIGGHKAKNT
SEDHLLAFYQTWEEVKHRKFDGFIITGAPIELLPYEDVTYWPEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYEL
KEKAFGVYRHRNLKPSSIYLNGFSDNFEVPVSRWTEVRRDDIEKSDELEILMESSEMGVCLVHEKRGRRLYMFNHVEYDS
TSLSDEYFRDVNTGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPFDVEEIGMDL

Sequences:

>Translated_307_residues
MPIKIPDTLPAFETLVQEGVRVMTETLAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGASPLQVELSLIRIGGHKAKNT
SEDHLLAFYQTWEEVKHRKFDGFIITGAPIELLPYEDVTYWPEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYEL
KEKAFGVYRHRNLKPSSIYLNGFSDNFEVPVSRWTEVRRDDIEKSDELEILMESSEMGVCLVHEKRGRRLYMFNHVEYDS
TSLSDEYFRDVNTGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPFDVEEIGMDL
>Mature_306_residues
PIKIPDTLPAFETLVQEGVRVMTETLAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGASPLQVELSLIRIGGHKAKNTS
EDHLLAFYQTWEEVKHRKFDGFIITGAPIELLPYEDVTYWPEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYELK
EKAFGVYRHRNLKPSSIYLNGFSDNFEVPVSRWTEVRRDDIEKSDELEILMESSEMGVCLVHEKRGRRLYMFNHVEYDST
SLSDEYFRDVNTGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPFDVEEIGMDL

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=308, Percent_Identity=44.1558441558442, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35736; Mature: 35605

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIPDTLPAFETLVQEGVRVMTETLAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVELSLIRIGGHKAKNTSEDHLLAFYQTWEEVKHRKFDGFIITGAPIELLPYEDVTY
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCC
WPEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYELKEKAFGVYRHRNLKPSSIYL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEE
NGFSDNFEVPVSRWTEVRRDDIEKSDELEILMESSEMGVCLVHEKRGRRLYMFNHVEYDS
ECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEECCC
TSLSDEYFRDVNTGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPFDV
CCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
EEIGMDL
HHCCCCC
>Mature Secondary Structure 
PIKIPDTLPAFETLVQEGVRVMTETLAIRQDIRPLQIGLLNLMPNKIKTELQMARLVGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVELSLIRIGGHKAKNTSEDHLLAFYQTWEEVKHRKFDGFIITGAPIELLPYEDVTY
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCC
WPEMQEILDWTETNVHSTMNVCWGAMAAIYHFHGVPKYELKEKAFGVYRHRNLKPSSIYL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEE
NGFSDNFEVPVSRWTEVRRDDIEKSDELEILMESSEMGVCLVHEKRGRRLYMFNHVEYDS
ECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEECCC
TSLSDEYFRDVNTGVPIKMPHNYFPHNDPALAPQNRWRSHAHLLFGNWINEIYQTTPFDV
CCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
EEIGMDL
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA