BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome.
Accession	NC_011369
Length	4,537,948

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The map label for this gene is ccmA [H]

Identifier: 209551310

GI number: 209551310

Start: 3867031

End: 3867678

Strand: Direct

Name: ccmA [H]

Synonym: Rleg2_3739

Alternate gene names: 209551310

Gene position: 3867031-3867678 (Clockwise)

Preceding gene: 209551306

Following gene: 209551311

Centisome position: 85.22

GC content: 60.65

Gene sequence:

>648_bases
ATGCATCTCACCGCCGAGAATCTGGCCGCAAGGCGCGGTGAGGATCTGATTTTCGTTAACATTTCCTTTCACTTGGCTGC
CGGCGAGGCGCTCATCCTGACAGGCAGAAATGGATCGGGAAAGTCCACTTTACTGCGCGTTGTTGCAGGCCTGCTCAAGC
CGGAAAAAGGCACTGTCATCGTCCGCACCGGAGCAGGCCGGGAAGACGGACATCCTGGCGAGTTGAGCCACTACCTCGGC
CATCGGAATGCGATGAAGAATGAACTTACGGTTGCAGAGAATTTGGATTTCTGGCGTCGTTTTCTCGGCGGTACCGGAAG
CTCTGCCGGCCTCTCCGTCGAGGACGCCACCGAGTCCGTCGGCCTTCCGGGTATTGCCCACCTTCCCTTCGGTTACCTCT
CCGCCGGCCAGCAGCGCCGTTTCGCCTTCGCCAAGCTGCTCGTCGCCCACCGCCCCATCTGGATCCTCGACGAACCCACC
GCCGCACTCGATGCCAGCGCCGACCGGCTGTTTGTCGGATTGATCGAAGCGCATCTGGCCAAAGGCGGCATCGTTCTGGC
GGCGACGCATCAGCCGCTGGGATTGAAGAATGCGCAGGAATTGAAGATGACGGGCTTTGCCGGTGTGGATGCGGGAGTGT
GGGGGTGA

Upstream 100 bases:

>100_bases
TCTTATAGATAATTTCCTAAAAACTTGCCATACCCGAGCAAGGTCAAAATCGGAGATTTTTTAAGCCCTCCGGAAGCCGA
AACGAAGAAAGAGCCGACGC

Downstream 100 bases:

>100_bases
TGTTTCTTCGTGTTGATACCCCCCTCTGCCCTGCCGGGCATCTCCCCCACAAGGGGGGAGATCGCCCAGGGGCGCCCTCT
TTCTCTAATGAAACGCGTCA

Product: cytochrome C biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MHLTAENLAARRGEDLIFVNISFHLAAGEALILTGRNGSGKSTLLRVVAGLLKPEKGTVIVRTGAGREDGHPGELSHYLG
HRNAMKNELTVAENLDFWRRFLGGTGSSAGLSVEDATESVGLPGIAHLPFGYLSAGQQRRFAFAKLLVAHRPIWILDEPT
AALDASADRLFVGLIEAHLAKGGIVLAATHQPLGLKNAQELKMTGFAGVDAGVWG

Sequences:

>Translated_215_residues
MHLTAENLAARRGEDLIFVNISFHLAAGEALILTGRNGSGKSTLLRVVAGLLKPEKGTVIVRTGAGREDGHPGELSHYLG
HRNAMKNELTVAENLDFWRRFLGGTGSSAGLSVEDATESVGLPGIAHLPFGYLSAGQQRRFAFAKLLVAHRPIWILDEPT
AALDASADRLFVGLIEAHLAKGGIVLAATHQPLGLKNAQELKMTGFAGVDAGVWG
>Mature_215_residues
MHLTAENLAARRGEDLIFVNISFHLAAGEALILTGRNGSGKSTLLRVVAGLLKPEKGTVIVRTGAGREDGHPGELSHYLG
HRNAMKNELTVAENLDFWRRFLGGTGSSAGLSVEDATESVGLPGIAHLPFGYLSAGQQRRFAFAKLLVAHRPIWILDEPT
AALDASADRLFVGLIEAHLAKGGIVLAATHQPLGLKNAQELKMTGFAGVDAGVWG

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=168, Percent_Identity=29.7619047619048, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI27477115, Length=172, Percent_Identity=27.3255813953488, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI105990541, Length=176, Percent_Identity=31.25, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI153792144, Length=177, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI6005701, Length=155, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27881501, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI30795238, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592956, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592915, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592898, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592978, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592964, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592971, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI116734710, Length=174, Percent_Identity=28.1609195402299, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI215820660, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI20143975, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150417984, Length=175, Percent_Identity=28, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87082064, Length=201, Percent_Identity=39.3034825870647, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87081782, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87081709, Length=172, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790739, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI1790467, Length=188, Percent_Identity=29.2553191489362, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI1788165, Length=174, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786253, Length=178, Percent_Identity=30.3370786516854, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48994943, Length=170, Percent_Identity=28.2352941176471, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790544, Length=195, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787029, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787041, Length=158, Percent_Identity=31.6455696202532, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788210, Length=188, Percent_Identity=30.3191489361702, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=183, Percent_Identity=31.1475409836066, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081834, Length=220, Percent_Identity=30.4545454545455, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788897, Length=186, Percent_Identity=30.6451612903226, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789032, Length=196, Percent_Identity=27.5510204081633, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788761, Length=174, Percent_Identity=29.3103448275862, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786563, Length=172, Percent_Identity=29.0697674418605, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789864, Length=193, Percent_Identity=29.5336787564767, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87082267, Length=155, Percent_Identity=27.741935483871, Blast_Score=60, Evalue=7e-11,
Organism=Escherichia coli, GI1787105, Length=178, Percent_Identity=26.9662921348315, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=200, Percent_Identity=29.5, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24666092, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI85724864, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580555, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI85816269, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580553, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161076682, Length=189, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076684, Length=189, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581617, Length=189, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581615, Length=189, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643674, Length=191, Percent_Identity=25.6544502617801, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574744, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221500419, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007184, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221500365, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920532, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24580930, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28574533, Length=188, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221512771, Length=191, Percent_Identity=26.1780104712042, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574150, Length=177, Percent_Identity=25.9887005649718, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI116007328, Length=177, Percent_Identity=25.9887005649718, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 22774; Mature: 22774

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTAENLAARRGEDLIFVNISFHLAAGEALILTGRNGSGKSTLLRVVAGLLKPEKGTVI
CCCCHHHHHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
VRTGAGREDGHPGELSHYLGHRNAMKNELTVAENLDFWRRFLGGTGSSAGLSVEDATESV
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCHHHC
GLPGIAHLPFGYLSAGQQRRFAFAKLLVAHRPIWILDEPTAALDASADRLFVGLIEAHLA
CCCCCHHCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHCCCCHHHHHHHHHHHHC
KGGIVLAATHQPLGLKNAQELKMTGFAGVDAGVWG
CCCEEEEECCCCCCCCCHHHEEEECCCCCCCCCCC
>Mature Secondary Structure
MHLTAENLAARRGEDLIFVNISFHLAAGEALILTGRNGSGKSTLLRVVAGLLKPEKGTVI
CCCCHHHHHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
VRTGAGREDGHPGELSHYLGHRNAMKNELTVAENLDFWRRFLGGTGSSAGLSVEDATESV
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCHHHC
GLPGIAHLPFGYLSAGQQRRFAFAKLLVAHRPIWILDEPTAALDASADRLFVGLIEAHLA
CCCCCHHCCCHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHCCCCHHHHHHHHHHHHC
KGGIVLAATHQPLGLKNAQELKMTGFAGVDAGVWG
CCCEEEEECCCCCCCCCHHHEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA