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The map label for this gene is phhB

Identifier: 209551300

GI number: 209551300

Start: 3855232

End: 3855537

Strand: Reverse

Name: phhB

Synonym: Rleg2_3728

Alternate gene names: NA

Gene position: 3855537-3855232 (Counterclockwise)

Preceding gene: 209551301

Following gene: 209551299

Centisome position: 84.96

GC content: 55.56

Gene sequence:

>306_bases
ATGAAAATGGAAAGACTGGAACGGGCTACGATCGAGGCTGAAATGGCTGGGCTTGCAGGCTGGGCGCTCAACGATGCGGC
TTCCTCGATATCGAAGACGTTCAAGTTTGCAAACTTTGTCGAGGCTTTCGGCTTCATGACCGAAGCAGCGATTAGGGCGG
AGAAGCTCAACCACCATCCTGAATGGTTCAACGTCTATTCCAGGGTGGATGTGACGCTGAACACCCATGATGCCGGCGGG
CTGACGGAGCTGGATTTCAAACTCGCCAAGGCGATGGAAAAGGCCGCGGCTCGACGCGGCGTTTGA

Upstream 100 bases:

>100_bases
ATCCTGTTCTAGCGGAGAACGGCATATATTGCCCATGCAAACGAAGAGGACGCTGATGTGTTTCATCGGTAGGCCTGTCG
ACAGATGAGAGGACCATGGC

Downstream 100 bases:

>100_bases
AGGCGGGGCCGATTGAAAGAGTGGGCGCCATCACCATATGTTCGCGGGGACGAAAGGATGGAAGGGATGGACGAAGTCAA
ATTCGGGGAAATTCTATTGC

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKMERLERATIEAEMAGLAGWALNDAASSISKTFKFANFVEAFGFMTEAAIRAEKLNHHPEWFNVYSRVDVTLNTHDAGG
LTELDFKLAKAMEKAAARRGV

Sequences:

>Translated_101_residues
MKMERLERATIEAEMAGLAGWALNDAASSISKTFKFANFVEAFGFMTEAAIRAEKLNHHPEWFNVYSRVDVTLNTHDAGG
LTELDFKLAKAMEKAAARRGV
>Mature_101_residues
MKMERLERATIEAEMAGLAGWALNDAASSISKTFKFANFVEAFGFMTEAAIRAEKLNHHPEWFNVYSRVDVTLNTHDAGG
LTELDFKLAKAMEKAAARRGV

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=79, Percent_Identity=58.2278481012658, Blast_Score=101, Evalue=1e-22,
Organism=Homo sapiens, GI4557831, Length=79, Percent_Identity=50.6329113924051, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115533705, Length=99, Percent_Identity=48.4848484848485, Blast_Score=104, Evalue=9e-24,
Organism=Drosophila melanogaster, GI45549100, Length=78, Percent_Identity=52.5641025641026, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_RHILW (B5ZTF5)

Other databases:

- EMBL:   CP001191
- RefSeq:   YP_002283217.1
- ProteinModelPortal:   B5ZTF5
- SMR:   B5ZTF5
- GeneID:   6982490
- GenomeReviews:   CP001191_GR
- KEGG:   rlt:Rleg2_3728
- HOGENOM:   HBG705804
- OMA:   FNVYSRV
- ProtClustDB:   PRK00823
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11222; Mature: 11222

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMERLERATIEAEMAGLAGWALNDAASSISKTFKFANFVEAFGFMTEAAIRAEKLNHHP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWFNVYSRVDVTLNTHDAGGLTELDFKLAKAMEKAAARRGV
HHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMERLERATIEAEMAGLAGWALNDAASSISKTFKFANFVEAFGFMTEAAIRAEKLNHHP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWFNVYSRVDVTLNTHDAGGLTELDFKLAKAMEKAAARRGV
HHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA