Click here to switch to the map view.

The map label for this gene is 209551272

Identifier: 209551272

GI number: 209551272

Start: 3827874

End: 3828581

Strand: Direct

Name: 209551272

Synonym: Rleg2_3700

Alternate gene names: NA

Gene position: 3827874-3828581 (Clockwise)

Preceding gene: 209551271

Following gene: 209551273

Centisome position: 84.35

GC content: 65.4

Gene sequence:

>708_bases
ATGCGCGTGCTCGTCACCCGCCCCGCGCATTCGGCTGAAAAAACCGCACAACGTCTGCGTGACATGGGCCACGAGCCGCT
GCTGCTGCCGCTGCGCCAGCCGGTGCACGACAGCACTGCTGCCGCGGCCGCGCTTGCAAGAACCAGCGGCGCGATCGCCG
TGACCAGCGCCGAAGCCGTCAGGGTCCTCTCCGCTCTCGGTGAGCAACTCCGTCCGCATTTTGCCCGCCCGCTTTTCGCG
GTTGGTGAGACGACGGCGGAGGCAGCGCGCAGCCTCGGCTTCGGTTCGGTCGCTTCATCTACCGGCAATGGCCGCGATCT
GGCCGAGCTGGTCGGCGCCCAGGCAGCGGACGGCCTGCTCTACCTTGCCGGCACGCCGCGCGCGGAAACCTTCGAAGCCG
GATTGCGCCAACGCGGCATCGGCTTTTCCGTCGCTGAATGTTATCGCATGCAGCCTGTCGTCCCCGGCCAGGCCGAGATC
GAAGCGATTTTTGCGGGCGGTCGGCCGGACGCGGTTCTCTTCTACTCACGGCAAACGGCCGACGATTTTTTTGGCGTGGC
GGAACTCCGTTTGGCCCTGCGGGAGGAAAGCGGAATCCGCCTTCTCTGCCTCAGCGAGGCGGTGGCGCAAGCCATCCCGG
CGGCTTTGAAAAAAAATGCGGCGATTGCGCCGATGCCGGATGAGAAAAGTCTTTTGTCGCTGCTTTGA

Upstream 100 bases:

>100_bases
GGCCACCGCCGCGATGCGGCCGCACTCGGCACCCGCGCCGGCCAGGACGTGCGCGCAAGGGCCGGCAGCGCCTTTTTCGA
CGACTGGCACTGACGCAGCC

Downstream 100 bases:

>100_bases
ATGCTTTAGCCGCCCAAATTTGATCTAACCTCTTCCCTTAATTGGCATCACTGTCTAGTTTCGTTGCAATGCAGGATAAA
GAGGACCTCATGGTATCGGG

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase Protein; Uroporphyrinogen III Synthase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRVLVTRPAHSAEKTAQRLRDMGHEPLLLPLRQPVHDSTAAAAALARTSGAIAVTSAEAVRVLSALGEQLRPHFARPLFA
VGETTAEAARSLGFGSVASSTGNGRDLAELVGAQAADGLLYLAGTPRAETFEAGLRQRGIGFSVAECYRMQPVVPGQAEI
EAIFAGGRPDAVLFYSRQTADDFFGVAELRLALREESGIRLLCLSEAVAQAIPAALKKNAAIAPMPDEKSLLSLL

Sequences:

>Translated_235_residues
MRVLVTRPAHSAEKTAQRLRDMGHEPLLLPLRQPVHDSTAAAAALARTSGAIAVTSAEAVRVLSALGEQLRPHFARPLFA
VGETTAEAARSLGFGSVASSTGNGRDLAELVGAQAADGLLYLAGTPRAETFEAGLRQRGIGFSVAECYRMQPVVPGQAEI
EAIFAGGRPDAVLFYSRQTADDFFGVAELRLALREESGIRLLCLSEAVAQAIPAALKKNAAIAPMPDEKSLLSLL
>Mature_235_residues
MRVLVTRPAHSAEKTAQRLRDMGHEPLLLPLRQPVHDSTAAAAALARTSGAIAVTSAEAVRVLSALGEQLRPHFARPLFA
VGETTAEAARSLGFGSVASSTGNGRDLAELVGAQAADGLLYLAGTPRAETFEAGLRQRGIGFSVAECYRMQPVVPGQAEI
EAIFAGGRPDAVLFYSRQTADDFFGVAELRLALREESGIRLLCLSEAVAQAIPAALKKNAAIAPMPDEKSLLSLL

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 24741; Mature: 24741

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTRPAHSAEKTAQRLRDMGHEPLLLPLRQPVHDSTAAAAALARTSGAIAVTSAEAV
CEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEHHHHH
RVLSALGEQLRPHFARPLFAVGETTAEAARSLGFGSVASSTGNGRDLAELVGAQAADGLL
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCHHCCCCCCHHHHHHHCCCCCCCEE
YLAGTPRAETFEAGLRQRGIGFSVAECYRMQPVVPGQAEIEAIFAGGRPDAVLFYSRQTA
EEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCC
DDFFGVAELRLALREESGIRLLCLSEAVAQAIPAALKKNAAIAPMPDEKSLLSLL
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
>Mature Secondary Structure
MRVLVTRPAHSAEKTAQRLRDMGHEPLLLPLRQPVHDSTAAAAALARTSGAIAVTSAEAV
CEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEHHHHH
RVLSALGEQLRPHFARPLFAVGETTAEAARSLGFGSVASSTGNGRDLAELVGAQAADGLL
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCHHCCCCCCHHHHHHHCCCCCCCEE
YLAGTPRAETFEAGLRQRGIGFSVAECYRMQPVVPGQAEIEAIFAGGRPDAVLFYSRQTA
EEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCC
DDFFGVAELRLALREESGIRLLCLSEAVAQAIPAALKKNAAIAPMPDEKSLLSLL
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA