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The map label for this gene is ccpA [H]

Identifier: 209551197

GI number: 209551197

Start: 3745086

End: 3746150

Strand: Reverse

Name: ccpA [H]

Synonym: Rleg2_3623

Alternate gene names: 209551197

Gene position: 3746150-3745086 (Counterclockwise)

Preceding gene: 209551198

Following gene: 209551196

Centisome position: 82.55

GC content: 63.57

Gene sequence:

>1065_bases
TTGGTAAAAGCTTTTCTCAAGCTACTTCAGAAGGAGGACGGTCTGAACATATCGGGAGGAAAAAGAGGCAGGATCACCAT
CCATGAGGTGGCGGCGGCTGCCGCGGTCAGCATCTCGACCGCGTCGAAGGCGCTCAACGACACCGGCCGAATGGGTGCGG
AAACGCGCGAGCGGGTGAAGCGGATCGCCGGCGAAATCGGCTATCGGCCGAATGCGCTGGCGAGAGGGCTGCTCAGCAAA
CGCAGCTTTACCATCGGGCTCTTGACCAACGACACCTACGGCCGTTTCACGCTGCCTGTGATGGCGGGTATTTCGGATGC
GCTGGTCGATCATGGGGTTTCGGTTTTCCTCTGCGCCATCGAAGACGATCCGGCGCTTGCCCAGATCCATGTCGATGCGA
TGCTCGACAAACAGGTCGACGGCATCATCGCCACGGGAAAGCGGCTGGACAGGCGTCTGCCTGTCGACCTGTCGAATTTG
CATGTGCCTGTCGTCTACGCCTTCACCGAGGGGACGCAGAACAGCGTTACCTTCCGTTCGGACGACGAACAGGGTGCGAG
GCTGGCGGTGGAATGGCTCGCCAAGATCGGACGGCGGCGGATCGCCCATATCACCGGGCCGGAGGATTTCTTCTCGGTGC
GGGAACGCGCCGGCGCCTATCACGAGGTGGCAGGCCACCGCGAGCCGGTGCTTTACGGCGTCTGGTCGGAAAGCTGGGGC
CATGAGGCGGTGGAGCAGCTTTGGAAGAGGCCGGGAGAAAAGCCCGACGCGCTGTTTTGCGGCAATGACCAGATTGCCCG
CGGTGCCGCCGATGCGCTGCGCGAGCGCGGCGTCAAGGTGCCGCAGGATGTCTCGGTGATCGGTTTCGACAATTGGGAGA
TTGTCGCGGCCCAGACGCGGCCGCCGCTGACGACGGTGGATATGGAGTTGAAGGAGCTCGGGCGGCAGGCCGGATTGACG
GTGCTGGCGCTTGCGGAAGGGCGGCCGGTCGAGCCGGGCGTGAGGAAATTGCCGTGCCGGCTGATCGTCCGGCAGTCATG
CGGGGGCAAAGCCCCCGCTGAGTGA

Upstream 100 bases:

>100_bases
CGCGTCGGTCCTTCTCTGCGTATACCCCTTGCCGCCGACCTCTCTCCCGGCGACAACGCCTGAGCAACATGAGAAAACCT
TTTCTCACTTGACATAGCGA

Downstream 100 bases:

>100_bases
GACCAAGGGAAAAGTATCAAGAGAATGAGCAAAGGCGCAGGGAGATGCGCCATATCGGGAGGAGTGTCATGATCAAGCGT
CTTTTGGCGGCGACCAGCAT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MVKAFLKLLQKEDGLNISGGKRGRITIHEVAAAAAVSISTASKALNDTGRMGAETRERVKRIAGEIGYRPNALARGLLSK
RSFTIGLLTNDTYGRFTLPVMAGISDALVDHGVSVFLCAIEDDPALAQIHVDAMLDKQVDGIIATGKRLDRRLPVDLSNL
HVPVVYAFTEGTQNSVTFRSDDEQGARLAVEWLAKIGRRRIAHITGPEDFFSVRERAGAYHEVAGHREPVLYGVWSESWG
HEAVEQLWKRPGEKPDALFCGNDQIARGAADALRERGVKVPQDVSVIGFDNWEIVAAQTRPPLTTVDMELKELGRQAGLT
VLALAEGRPVEPGVRKLPCRLIVRQSCGGKAPAE

Sequences:

>Translated_354_residues
MVKAFLKLLQKEDGLNISGGKRGRITIHEVAAAAAVSISTASKALNDTGRMGAETRERVKRIAGEIGYRPNALARGLLSK
RSFTIGLLTNDTYGRFTLPVMAGISDALVDHGVSVFLCAIEDDPALAQIHVDAMLDKQVDGIIATGKRLDRRLPVDLSNL
HVPVVYAFTEGTQNSVTFRSDDEQGARLAVEWLAKIGRRRIAHITGPEDFFSVRERAGAYHEVAGHREPVLYGVWSESWG
HEAVEQLWKRPGEKPDALFCGNDQIARGAADALRERGVKVPQDVSVIGFDNWEIVAAQTRPPLTTVDMELKELGRQAGLT
VLALAEGRPVEPGVRKLPCRLIVRQSCGGKAPAE
>Mature_354_residues
MVKAFLKLLQKEDGLNISGGKRGRITIHEVAAAAAVSISTASKALNDTGRMGAETRERVKRIAGEIGYRPNALARGLLSK
RSFTIGLLTNDTYGRFTLPVMAGISDALVDHGVSVFLCAIEDDPALAQIHVDAMLDKQVDGIIATGKRLDRRLPVDLSNL
HVPVVYAFTEGTQNSVTFRSDDEQGARLAVEWLAKIGRRRIAHITGPEDFFSVRERAGAYHEVAGHREPVLYGVWSESWG
HEAVEQLWKRPGEKPDALFCGNDQIARGAADALRERGVKVPQDVSVIGFDNWEIVAAQTRPPLTTVDMELKELGRQAGLT
VLALAEGRPVEPGVRKLPCRLIVRQSCGGKAPAE

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=31.2121212121212, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786540, Length=330, Percent_Identity=30.6060606060606, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=31.8181818181818, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789068, Length=331, Percent_Identity=31.4199395770393, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=29.3939393939394, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787906, Length=296, Percent_Identity=32.7702702702703, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=26.6233766233766, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=26.5060240963855, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=27.6527331189711, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=27.1293375394322, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=25.6965944272446, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789456, Length=349, Percent_Identity=26.9340974212034, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786268, Length=336, Percent_Identity=25.297619047619, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=24.6200607902736, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38540; Mature: 38540

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAFLKLLQKEDGLNISGGKRGRITIHEVAAAAAVSISTASKALNDTGRMGAETRERVK
CHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIAGEIGYRPNALARGLLSKRSFTIGLLTNDTYGRFTLPVMAGISDALVDHGVSVFLCAI
HHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHCHHHHHHHCCCEEEEEEE
EDDPALAQIHVDAMLDKQVDGIIATGKRLDRRLPVDLSNLHVPVVYAFTEGTQNSVTFRS
CCCCCEEEEEHHHHHHHHHCCEECCCHHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEEC
DDEQGARLAVEWLAKIGRRRIAHITGPEDFFSVRERAGAYHEVAGHREPVLYGVWSESWG
CCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCC
HEAVEQLWKRPGEKPDALFCGNDQIARGAADALRERGVKVPQDVSVIGFDNWEIVAAQTR
HHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCC
PPLTTVDMELKELGRQAGLTVLALAEGRPVEPGVRKLPCRLIVRQSCGGKAPAE
CCCEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVKAFLKLLQKEDGLNISGGKRGRITIHEVAAAAAVSISTASKALNDTGRMGAETRERVK
CHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIAGEIGYRPNALARGLLSKRSFTIGLLTNDTYGRFTLPVMAGISDALVDHGVSVFLCAI
HHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHCHHHHHHHCCCEEEEEEE
EDDPALAQIHVDAMLDKQVDGIIATGKRLDRRLPVDLSNLHVPVVYAFTEGTQNSVTFRS
CCCCCEEEEEHHHHHHHHHCCEECCCHHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEEC
DDEQGARLAVEWLAKIGRRRIAHITGPEDFFSVRERAGAYHEVAGHREPVLYGVWSESWG
CCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCC
HEAVEQLWKRPGEKPDALFCGNDQIARGAADALRERGVKVPQDVSVIGFDNWEIVAAQTR
HHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCC
PPLTTVDMELKELGRQAGLTVLALAEGRPVEPGVRKLPCRLIVRQSCGGKAPAE
CCCEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]