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The map label for this gene is dgoR [H]

Identifier: 209551054

GI number: 209551054

Start: 3593931

End: 3594686

Strand: Direct

Name: dgoR [H]

Synonym: Rleg2_3478

Alternate gene names: 209551054

Gene position: 3593931-3594686 (Clockwise)

Preceding gene: 209551044

Following gene: 209551055

Centisome position: 79.2

GC content: 63.1

Gene sequence:

>756_bases
TTGGAAACAAACGAGCGACAGGACGGGGCCGAAAGCCCCGGCATCGAGCGCCGTCCACGTGTACGCCGCAACGTCACCGC
GGCGATCGCACAGGATATCTGCGCGGAGCGGTATCCCTCAGGCTCGCCGTTGCCCCGCGAAAACGATCTCTGCCAACTCT
ACGGCGTCAGCCGCACCGTCATCCGCGAATCGCTGAAAGTGCTGGAATCCAAGGGCCTTGTCCGCGGAAAGCCGCGGATC
GGCACCACCGTCTGCGATCGGGACGACTGGAATATCCTGGATGCCGACGTGCTCGATTGGATTGGTCCTTATATCAAGGA
TTTCGACCTGCTCGGCTGCATTCTCGAAGCTCGCCGCACCATCGAGCCGGCAGCGGCGGAATATGCCGCCGAGCGCGCCA
GCGCCCAGGAGATCGCCGATCTCGACAAGGCTTGGCGGCAGATGCGCGACAGTGCCGGCGATCCGGAAAGCTTCACCGAT
GCCGACGTCATGTTTCATACGGTGCTGCTGACCGCCAGCCACAACCAGGTCTTCCGCCGCCTGTCGAGCGCCATTCATGC
GGCGCTGAAATATGCGCTGCATGCCTCCAACATCGGCGTCGAGAATCGCGAGGATGCGGTGCTCGTTCACGGTCAATTGG
TCGAGGCCCTGCGCATGCGCGACAAGACAGGCGCCCGCGACTGCGCCAACCGCATGCTCGATCTTGCGGTGCGCGACCTT
GCCGCCGCCGAAAAGGCGATCGGCAGAACGAAATAA

Upstream 100 bases:

>100_bases
TACGATATTGACGAGGTGCTGGAGGAAGCGTCGCAAAGCGGATCGAATTCGGATAATGAGGTTCGATTGCCTGGCGCCAG
AGATAGAGCGGAGAGGTGAG

Downstream 100 bases:

>100_bases
GCAATCCGTGGCTGGGCCGCCGGTCAAAAATCTGAAGAGAGACTGAAGAGCAGCGATGAAGATCACCAAACTCACCACCT
ATATCGTTCCGCCGCGCTGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
METNERQDGAESPGIERRPRVRRNVTAAIAQDICAERYPSGSPLPRENDLCQLYGVSRTVIRESLKVLESKGLVRGKPRI
GTTVCDRDDWNILDADVLDWIGPYIKDFDLLGCILEARRTIEPAAAEYAAERASAQEIADLDKAWRQMRDSAGDPESFTD
ADVMFHTVLLTASHNQVFRRLSSAIHAALKYALHASNIGVENREDAVLVHGQLVEALRMRDKTGARDCANRMLDLAVRDL
AAAEKAIGRTK

Sequences:

>Translated_251_residues
METNERQDGAESPGIERRPRVRRNVTAAIAQDICAERYPSGSPLPRENDLCQLYGVSRTVIRESLKVLESKGLVRGKPRI
GTTVCDRDDWNILDADVLDWIGPYIKDFDLLGCILEARRTIEPAAAEYAAERASAQEIADLDKAWRQMRDSAGDPESFTD
ADVMFHTVLLTASHNQVFRRLSSAIHAALKYALHASNIGVENREDAVLVHGQLVEALRMRDKTGARDCANRMLDLAVRDL
AAAEKAIGRTK
>Mature_251_residues
METNERQDGAESPGIERRPRVRRNVTAAIAQDICAERYPSGSPLPRENDLCQLYGVSRTVIRESLKVLESKGLVRGKPRI
GTTVCDRDDWNILDADVLDWIGPYIKDFDLLGCILEARRTIEPAAAEYAAERASAQEIADLDKAWRQMRDSAGDPESFTD
ADVMFHTVLLTASHNQVFRRLSSAIHAALKYALHASNIGVENREDAVLVHGQLVEALRMRDKTGARDCANRMLDLAVRDL
AAAEKAIGRTK

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=217, Percent_Identity=33.6405529953917, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI48994961, Length=213, Percent_Identity=29.5774647887324, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=28.6343612334802, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27911; Mature: 27911

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNERQDGAESPGIERRPRVRRNVTAAIAQDICAERYPSGSPLPRENDLCQLYGVSRTV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IRESLKVLESKGLVRGKPRIGTTVCDRDDWNILDADVLDWIGPYIKDFDLLGCILEARRT
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
IEPAAAEYAAERASAQEIADLDKAWRQMRDSAGDPESFTDADVMFHTVLLTASHNQVFRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
LSSAIHAALKYALHASNIGVENREDAVLVHGQLVEALRMRDKTGARDCANRMLDLAVRDL
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAAEKAIGRTK
HHHHHHHCCCC
>Mature Secondary Structure
METNERQDGAESPGIERRPRVRRNVTAAIAQDICAERYPSGSPLPRENDLCQLYGVSRTV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IRESLKVLESKGLVRGKPRIGTTVCDRDDWNILDADVLDWIGPYIKDFDLLGCILEARRT
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
IEPAAAEYAAERASAQEIADLDKAWRQMRDSAGDPESFTDADVMFHTVLLTASHNQVFRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
LSSAIHAALKYALHASNIGVENREDAVLVHGQLVEALRMRDKTGARDCANRMLDLAVRDL
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAAEKAIGRTK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]