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The map label for this gene is degA [H]

Identifier: 209550989

GI number: 209550989

Start: 3527980

End: 3529002

Strand: Reverse

Name: degA [H]

Synonym: Rleg2_3413

Alternate gene names: 209550989

Gene position: 3529002-3527980 (Counterclockwise)

Preceding gene: 209550990

Following gene: 209550988

Centisome position: 77.77

GC content: 64.32

Gene sequence:

>1023_bases
ATGAGGCCAACAGTTCACGATATCGCCGCCGCCGCCGGGGTCAGTCTTGCGACTGTCGACCGGGTTCTCAACCAGCGCCC
GGGTGTGCGTCACGTTACGCGGGAGAAGGTCGAGACCGCAATCCGCGATCTCGGTTATATCAGGGACGTCGCCGCCGCCA
ATCTCGCCAAGGGGCGTACCTATCCGCTGGTCTTCATCCTGCCGGCCAGTGACAATTCCTTCATGCATGGGCTGAATGCC
GAGATCCGCCAGGCCGTTCTCCGATCGCCGGCGGAGCGCACCGATATCCGCATTGTCGAAGTCCCGGCCTTCGATCCGGC
CGCCCTCGTTTCGGTGCTCGAAGAGCTTGCCCGCGAAAAGCCTTGCGGCATCGCGATGGTCGCGACCGATGCGCCTGAGG
TGCGCGCCGTCGTCGACAGACTGGTGCGCGAGCGCTTTCCCATCGTCACCCTGGTTTCCGATCTCACCGGATCGCTTCGC
CATCACTATGCCGGCGTCGACAATATCGCGGCCGGCCGGACGGCGGCCCGTCTGCTCGGCCGCTTTCTCGGCCCGCGAAA
GGGTGAGATCGCCGTGCTCGCCGGCTCCATGCTGGTGCGCGACCATCGCGAGCGGCTGGAAGGTTTTGCCGCTGTGATGG
CGGAAGAATTTCCCGATCTTGCGATCCTGCCGGTTCTCGAAGGCCGCGACGACCCCGAGGTCGCCAATAGGCTGGTTGCC
GATGCGCTCGGAAATACCGGCATCGTCGGCATCTACAGCCTCGGTGCCGGCAATCGTGGCCTCATCCGGGCGCTGAAGGA
GAAGGCCGCCGACCGGACGCTGACGGTGATTGCCCATGAACTGACCGCCCATACGCGCGCAGCGCTCATCGACAACACGA
TCGATGCGATCCTCAACCAGGACGCCGGCCATGAGGTGCGCAGCGCCATCCGCATATTGAAAGCCAAGGCGGACGGGCTT
GCCGTCATCGCAGCGCAGGAGCGCATCCGCCTCGACATATTCCTGAAGGACAATCTGCCGTAA

Upstream 100 bases:

>100_bases
AGCAGACGGCCGGCCGGAAAAACAGTGCGCCAATCGGCCTGTTCGATTTTTTGATTTACGTACATCAAATTTGGCGCTAA
TGGTCTCGTCAGGAGGAATG

Downstream 100 bases:

>100_bases
CGGCAAAGGAGAATACCCCATGTATCTCGGTCTCGATCTCGGAACCTCCGGCGTCAAGGCGATGCTGATCGACGGCGATC
AGAAGATCGTCGGCTCGGCC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRPTVHDIAAAAGVSLATVDRVLNQRPGVRHVTREKVETAIRDLGYIRDVAAANLAKGRTYPLVFILPASDNSFMHGLNA
EIRQAVLRSPAERTDIRIVEVPAFDPAALVSVLEELAREKPCGIAMVATDAPEVRAVVDRLVRERFPIVTLVSDLTGSLR
HHYAGVDNIAAGRTAARLLGRFLGPRKGEIAVLAGSMLVRDHRERLEGFAAVMAEEFPDLAILPVLEGRDDPEVANRLVA
DALGNTGIVGIYSLGAGNRGLIRALKEKAADRTLTVIAHELTAHTRAALIDNTIDAILNQDAGHEVRSAIRILKAKADGL
AVIAAQERIRLDIFLKDNLP

Sequences:

>Translated_340_residues
MRPTVHDIAAAAGVSLATVDRVLNQRPGVRHVTREKVETAIRDLGYIRDVAAANLAKGRTYPLVFILPASDNSFMHGLNA
EIRQAVLRSPAERTDIRIVEVPAFDPAALVSVLEELAREKPCGIAMVATDAPEVRAVVDRLVRERFPIVTLVSDLTGSLR
HHYAGVDNIAAGRTAARLLGRFLGPRKGEIAVLAGSMLVRDHRERLEGFAAVMAEEFPDLAILPVLEGRDDPEVANRLVA
DALGNTGIVGIYSLGAGNRGLIRALKEKAADRTLTVIAHELTAHTRAALIDNTIDAILNQDAGHEVRSAIRILKAKADGL
AVIAAQERIRLDIFLKDNLP
>Mature_340_residues
MRPTVHDIAAAAGVSLATVDRVLNQRPGVRHVTREKVETAIRDLGYIRDVAAANLAKGRTYPLVFILPASDNSFMHGLNA
EIRQAVLRSPAERTDIRIVEVPAFDPAALVSVLEELAREKPCGIAMVATDAPEVRAVVDRLVRERFPIVTLVSDLTGSLR
HHYAGVDNIAAGRTAARLLGRFLGPRKGEIAVLAGSMLVRDHRERLEGFAAVMAEEFPDLAILPVLEGRDDPEVANRLVA
DALGNTGIVGIYSLGAGNRGLIRALKEKAADRTLTVIAHELTAHTRAALIDNTIDAILNQDAGHEVRSAIRILKAKADGL
AVIAAQERIRLDIFLKDNLP

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36730; Mature: 36730

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTVHDIAAAAGVSLATVDRVLNQRPGVRHVTREKVETAIRDLGYIRDVAAANLAKGRT
CCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YPLVFILPASDNSFMHGLNAEIRQAVLRSPAERTDIRIVEVPAFDPAALVSVLEELAREK
CCEEEEEECCCCCHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
PCGIAMVATDAPEVRAVVDRLVRERFPIVTLVSDLTGSLRHHYAGVDNIAAGRTAARLLG
CCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RFLGPRKGEIAVLAGSMLVRDHRERLEGFAAVMAEEFPDLAILPVLEGRDDPEVANRLVA
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
DALGNTGIVGIYSLGAGNRGLIRALKEKAADRTLTVIAHELTAHTRAALIDNTIDAILNQ
HHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAGHEVRSAIRILKAKADGLAVIAAQERIRLDIFLKDNLP
CCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCC
>Mature Secondary Structure
MRPTVHDIAAAAGVSLATVDRVLNQRPGVRHVTREKVETAIRDLGYIRDVAAANLAKGRT
CCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YPLVFILPASDNSFMHGLNAEIRQAVLRSPAERTDIRIVEVPAFDPAALVSVLEELAREK
CCEEEEEECCCCCHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
PCGIAMVATDAPEVRAVVDRLVRERFPIVTLVSDLTGSLRHHYAGVDNIAAGRTAARLLG
CCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RFLGPRKGEIAVLAGSMLVRDHRERLEGFAAVMAEEFPDLAILPVLEGRDDPEVANRLVA
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
DALGNTGIVGIYSLGAGNRGLIRALKEKAADRTLTVIAHELTAHTRAALIDNTIDAILNQ
HHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAGHEVRSAIRILKAKADGLAVIAAQERIRLDIFLKDNLP
CCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]