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The map label for this gene is xylB [H]

Identifier: 209550988

GI number: 209550988

Start: 3526506

End: 3527960

Strand: Reverse

Name: xylB [H]

Synonym: Rleg2_3412

Alternate gene names: 209550988

Gene position: 3527960-3526506 (Counterclockwise)

Preceding gene: 209550989

Following gene: 209550987

Centisome position: 77.74

GC content: 66.94

Gene sequence:

>1455_bases
ATGTATCTCGGTCTCGATCTCGGAACCTCCGGCGTCAAGGCGATGCTGATCGACGGCGATCAGAAGATCGTCGGCTCGGC
CAATGGTTCGCTCGACGTCTCGCGTCCGCATTCCGGCTGGTCGGAGCAGGAGCCGGCCCACTGGGTGCGTGCCACCGAAG
AGGCCGTTGCCGGCCTGAAGGCAAAACATCCGAAAGAGCTTGCCGCGGTCAAGGGCATCGGCCTTTCCGGCCAGATGCAC
GGCGCGACGCTGATCGATGCCGCCGACAAGGCGCTGCGCCCCTGCATCCTCTGGAACGACACGCGCAGCCACGTCGAGGC
TGCAGCCCTCGATGCCGACCCGCGCTTCCGCGCGCTCACCGGCAACATCGTCTTCCCCGGCTTCACGGCGCCGAAGCTCG
CCTGGGTCGAGAAGCACGAGCGCGATGTTTTCGCCAAGATCGCCAAGGTGCTGCTGCCGAAGGACTATCTGCGTCTGTGG
CTGACCGGCGACCATATCTCCGAAATGTCGGATTCGGCCGGCACCTCCTGGCTCGACACCGGCAAGCGCGCCTGGTCGTC
CGAACTGCTCGCCGCCACCAATCTTTCCGAGGAGCAGATGCCGGCGCTTGTCGAGGGCACCGCGCAGGCTGGTCAGCTGC
GGGCAGAACTTGTGGCGCAATGGGGGATCTCCGGCAATGTCGTCGTCGCCGGCGGGGCCGGCGACAATGCCGCCTCGGCC
TGCGGCATGGGCACGGTCAGCGATGGCGCCGCCTTCGTCTCGCTCGGCACGTCGGGCGTGCTTTTTGCCGCCAATGGCTC
CTATCTGCCGAAGCCGGAAAGTGCCGTGCATGCCTTCTGCCACGCGCTGCCGAACACCTGGCATCAGATGGGCGTCATCC
TCTCGGCCACCGATGCGCTCAACTGGCATTCAGGGGTGACCGGCAAGTCGGCGGCCGATCTCACCGGCGAACTCGGCGAG
ACGTTGAAGGCGCCGACCGGCGTCACCTTCCTGCCCTATCTTTCCGGCGAGCGCACGCCGCACAATGATGCCGTCATCCG
CGGCGCCTTCATCGGCCTCGAACATGAAAGCAGCCGTGCCGTGCTCACCCAGGCGGTGCTCGAAGGTGTGGCCTTTGCCA
TCCGCGACAATCTCGAAGCGCTGCGTTCGGCCGGCACCGGTATCTCCCGCGTCACGGCGATCGGCGGCGGTTCGCGCTCG
CATTACTGGCTGGCGTCGATCGCGACCGCGCTCGGCGTTCCGGTCGACCTGCCCGCCGACGGCGATTTCGGCGCGGCCTT
CGGCGCCGCCCGCCTCGGCCTGATTGCTGCGACGGGTGCCGATCCGATTGCCGTCTGCACGCCGCCGGTGACATCAGGCA
CGATCGAGCCGGTGTCGGCGCTGAGCGGCGCTTACGAGGATGCCTATACGCGCTACCGCGCAGTTTATCCGGCGGTCAAA
TCGCTGGCGCATTGA

Upstream 100 bases:

>100_bases
GCCAAGGCGGACGGGCTTGCCGTCATCGCAGCGCAGGAGCGCATCCGCCTCGACATATTCCTGAAGGACAATCTGCCGTA
ACGGCAAAGGAGAATACCCC

Downstream 100 bases:

>100_bases
GAGTTTGAGCTAGCGGCCCCCTCATCCGACCCTTCGGGCCACCTTCTCCCCGAGGGGAGAAGGTAAAAGAGGCGCTGCGG
CGAACCTCTTCTCCCACTCG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYLGLDLGTSGVKAMLIDGDQKIVGSANGSLDVSRPHSGWSEQEPAHWVRATEEAVAGLKAKHPKELAAVKGIGLSGQMH
GATLIDAADKALRPCILWNDTRSHVEAAALDADPRFRALTGNIVFPGFTAPKLAWVEKHERDVFAKIAKVLLPKDYLRLW
LTGDHISEMSDSAGTSWLDTGKRAWSSELLAATNLSEEQMPALVEGTAQAGQLRAELVAQWGISGNVVVAGGAGDNAASA
CGMGTVSDGAAFVSLGTSGVLFAANGSYLPKPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGKSAADLTGELGE
TLKAPTGVTFLPYLSGERTPHNDAVIRGAFIGLEHESSRAVLTQAVLEGVAFAIRDNLEALRSAGTGISRVTAIGGGSRS
HYWLASIATALGVPVDLPADGDFGAAFGAARLGLIAATGADPIAVCTPPVTSGTIEPVSALSGAYEDAYTRYRAVYPAVK
SLAH

Sequences:

>Translated_484_residues
MYLGLDLGTSGVKAMLIDGDQKIVGSANGSLDVSRPHSGWSEQEPAHWVRATEEAVAGLKAKHPKELAAVKGIGLSGQMH
GATLIDAADKALRPCILWNDTRSHVEAAALDADPRFRALTGNIVFPGFTAPKLAWVEKHERDVFAKIAKVLLPKDYLRLW
LTGDHISEMSDSAGTSWLDTGKRAWSSELLAATNLSEEQMPALVEGTAQAGQLRAELVAQWGISGNVVVAGGAGDNAASA
CGMGTVSDGAAFVSLGTSGVLFAANGSYLPKPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGKSAADLTGELGE
TLKAPTGVTFLPYLSGERTPHNDAVIRGAFIGLEHESSRAVLTQAVLEGVAFAIRDNLEALRSAGTGISRVTAIGGGSRS
HYWLASIATALGVPVDLPADGDFGAAFGAARLGLIAATGADPIAVCTPPVTSGTIEPVSALSGAYEDAYTRYRAVYPAVK
SLAH
>Mature_484_residues
MYLGLDLGTSGVKAMLIDGDQKIVGSANGSLDVSRPHSGWSEQEPAHWVRATEEAVAGLKAKHPKELAAVKGIGLSGQMH
GATLIDAADKALRPCILWNDTRSHVEAAALDADPRFRALTGNIVFPGFTAPKLAWVEKHERDVFAKIAKVLLPKDYLRLW
LTGDHISEMSDSAGTSWLDTGKRAWSSELLAATNLSEEQMPALVEGTAQAGQLRAELVAQWGISGNVVVAGGAGDNAASA
CGMGTVSDGAAFVSLGTSGVLFAANGSYLPKPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGKSAADLTGELGE
TLKAPTGVTFLPYLSGERTPHNDAVIRGAFIGLEHESSRAVLTQAVLEGVAFAIRDNLEALRSAGTGISRVTAIGGGSRS
HYWLASIATALGVPVDLPADGDFGAAFGAARLGLIAATGADPIAVCTPPVTSGTIEPVSALSGAYEDAYTRYRAVYPAVK
SLAH

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=409, Percent_Identity=22.0048899755501, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI88196792, Length=478, Percent_Identity=21.5481171548117, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI42794763, Length=442, Percent_Identity=20.3619909502262, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI18860918, Length=459, Percent_Identity=23.0936819172113, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789987, Length=486, Percent_Identity=47.119341563786, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790005, Length=504, Percent_Identity=26.1904761904762, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790361, Length=453, Percent_Identity=21.4128035320088, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789168, Length=446, Percent_Identity=23.0941704035874, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=422, Percent_Identity=23.9336492890995, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321633, Length=347, Percent_Identity=25.3602305475504, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655555, Length=471, Percent_Identity=23.5668789808917, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655560, Length=471, Percent_Identity=23.5668789808917, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655570, Length=471, Percent_Identity=23.5668789808917, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655574, Length=471, Percent_Identity=23.5668789808917, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655565, Length=471, Percent_Identity=23.5668789808917, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17864214, Length=451, Percent_Identity=22.3946784922395, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 50287; Mature: 50287

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGLDLGTSGVKAMLIDGDQKIVGSANGSLDVSRPHSGWSEQEPAHWVRATEEAVAGLK
CEEEEECCCCCCEEEEEECCCEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
AKHPKELAAVKGIGLSGQMHGATLIDAADKALRPCILWNDTRSHVEAAALDADPRFRALT
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLAWVEKHERDVFAKIAKVLLPKDYLRLWLTGDHISEMSDSAGTSWLDT
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHH
GKRAWSSELLAATNLSEEQMPALVEGTAQAGQLRAELVAQWGISGNVVVAGGAGDNAASA
HHHHHHHHHHHHCCCCHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
CGMGTVSDGAAFVSLGTSGVLFAANGSYLPKPESAVHAFCHALPNTWHQMGVILSATDAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHCEEEEECCCC
NWHSGVTGKSAADLTGELGETLKAPTGVTFLPYLSGERTPHNDAVIRGAFIGLEHESSRA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCHH
VLTQAVLEGVAFAIRDNLEALRSAGTGISRVTAIGGGSRSHYWLASIATALGVPVDLPAD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAATGADPIAVCTPPVTSGTIEPVSALSGAYEDAYTRYRAVYPAVK
CCCCHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLAH
HHCC
>Mature Secondary Structure
MYLGLDLGTSGVKAMLIDGDQKIVGSANGSLDVSRPHSGWSEQEPAHWVRATEEAVAGLK
CEEEEECCCCCCEEEEEECCCEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
AKHPKELAAVKGIGLSGQMHGATLIDAADKALRPCILWNDTRSHVEAAALDADPRFRALT
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLAWVEKHERDVFAKIAKVLLPKDYLRLWLTGDHISEMSDSAGTSWLDT
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHH
GKRAWSSELLAATNLSEEQMPALVEGTAQAGQLRAELVAQWGISGNVVVAGGAGDNAASA
HHHHHHHHHHHHCCCCHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
CGMGTVSDGAAFVSLGTSGVLFAANGSYLPKPESAVHAFCHALPNTWHQMGVILSATDAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHCEEEEECCCC
NWHSGVTGKSAADLTGELGETLKAPTGVTFLPYLSGERTPHNDAVIRGAFIGLEHESSRA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCHH
VLTQAVLEGVAFAIRDNLEALRSAGTGISRVTAIGGGSRSHYWLASIATALGVPVDLPAD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAATGADPIAVCTPPVTSGTIEPVSALSGAYEDAYTRYRAVYPAVK
CCCCHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLAH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]