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The map label for this gene is tdcB [H]

Identifier: 209550858

GI number: 209550858

Start: 3371258

End: 3372232

Strand: Direct

Name: tdcB [H]

Synonym: Rleg2_3282

Alternate gene names: 209550858

Gene position: 3371258-3372232 (Clockwise)

Preceding gene: 209550857

Following gene: 209550861

Centisome position: 74.29

GC content: 66.56

Gene sequence:

>975_bases
ATGGCCAGCATTGAAATGATTGTCGCCGCCCGCGCCCGTCTGCGCGGCCACGCGAGGCGCACGCCGCTTCTTTCCTCTCC
CTTCCTGAACGAGATCGCCGGCCGGCGCGTGTTCGTGAAGGCGGAATGCCTGCAGCATTCCGGCTCGTTCAAGTTTCGCG
GCGGCTGGTCCGCCGTCTCCGGCCTCGATCCGGTGATACGCTCGAAGGGCGTTATCGCCTTCTCCTCCGGCAACCATGCC
CAGGGTGTCGCCCTTGCCGCCAAGCTGCACAACGTGCCCTCCGTCATCATCATGCCGAGCGACGCGCCGAAGCTGAAGAT
CGCCAATACCCGCGCCTTCGGCGCCGAAGTGGTGCTCTACGACCGTGTCAACGAGGACCGCGACGAGATCGGCGCGAGAC
TGTCGGCCGAGCGCGGCCTGACGCTGATCAAGCCCTTCGACGAACCGCTGGTGATCGCCGGCCAGGGCACCACCGGCCTC
GAAATCTCCGAGCAGGCGGAAGAGGAAGGCGTGACATCAGCCGAAATCCTCGTGCCCTGCGGCGGCGGCGGATTGACCTC
CGGCATCGCGCTCGCGCTTGAAGCCAGCGCTCCCGGCTTTCGCGTCCGCCCCTGCGAGCCCAAGGATTTCGATGACACCG
CCCGCTCGCTCGCCTCCGGCAGGATCGAGCGCAACGTGGCGGTATCAGGCTCGATCTGCGATGCGATCGTCACGCCGCAG
CCGGGAAATATCACCTTCCCAATCCTCAAGCGCCTCGCCGGTGCCGGCATCGTCGTCACCGACGAGGAGGCGCTGCGCGC
CATGGCGCTCGCCTTCGTCAGGTTGAAGATTGTCGTCGAGCCCGGCGGCGCGGTGGCGCTCGCTGCCGCCCTCTTCCATG
GCGAAGCGCTGGAAAGCGACACGGTGGTCGTCGTCACCTCCGGCGGCAATGTCGATTCCGATATCTTCGCCATGGCGCTG
GAACGCTTCGGCTGA

Upstream 100 bases:

>100_bases
AACGCGACGAGCCATTCATGTCACGGTGACAAAGTCGCCGTTCACAAACGGCTGGCCGCGCCCTAAGCATGAGCGAACCC
GCAAGCAGGACGATTCCCGA

Downstream 100 bases:

>100_bases
GGGCATCGGGAAGCAGCCAACCACGCGACAGCCCCGATATCAAATGCAAGTCGTGAGGCATCCGGCTCCCTTGAGCCGAA
TGCCCTATTCTGCCGTCAGA

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MASIEMIVAARARLRGHARRTPLLSSPFLNEIAGRRVFVKAECLQHSGSFKFRGGWSAVSGLDPVIRSKGVIAFSSGNHA
QGVALAAKLHNVPSVIIMPSDAPKLKIANTRAFGAEVVLYDRVNEDRDEIGARLSAERGLTLIKPFDEPLVIAGQGTTGL
EISEQAEEEGVTSAEILVPCGGGGLTSGIALALEASAPGFRVRPCEPKDFDDTARSLASGRIERNVAVSGSICDAIVTPQ
PGNITFPILKRLAGAGIVVTDEEALRAMALAFVRLKIVVEPGGAVALAAALFHGEALESDTVVVVTSGGNVDSDIFAMAL
ERFG

Sequences:

>Translated_324_residues
MASIEMIVAARARLRGHARRTPLLSSPFLNEIAGRRVFVKAECLQHSGSFKFRGGWSAVSGLDPVIRSKGVIAFSSGNHA
QGVALAAKLHNVPSVIIMPSDAPKLKIANTRAFGAEVVLYDRVNEDRDEIGARLSAERGLTLIKPFDEPLVIAGQGTTGL
EISEQAEEEGVTSAEILVPCGGGGLTSGIALALEASAPGFRVRPCEPKDFDDTARSLASGRIERNVAVSGSICDAIVTPQ
PGNITFPILKRLAGAGIVVTDEEALRAMALAFVRLKIVVEPGGAVALAAALFHGEALESDTVVVVTSGGNVDSDIFAMAL
ERFG
>Mature_323_residues
ASIEMIVAARARLRGHARRTPLLSSPFLNEIAGRRVFVKAECLQHSGSFKFRGGWSAVSGLDPVIRSKGVIAFSSGNHAQ
GVALAAKLHNVPSVIIMPSDAPKLKIANTRAFGAEVVLYDRVNEDRDEIGARLSAERGLTLIKPFDEPLVIAGQGTTGLE
ISEQAEEEGVTSAEILVPCGGGGLTSGIALALEASAPGFRVRPCEPKDFDDTARSLASGRIERNVAVSGSICDAIVTPQP
GNITFPILKRLAGAGIVVTDEEALRAMALAFVRLKIVVEPGGAVALAAALFHGEALESDTVVVVTSGGNVDSDIFAMALE
RFG

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=309, Percent_Identity=36.2459546925566, Blast_Score=191, Evalue=6e-49,
Organism=Escherichia coli, GI1789505, Length=313, Percent_Identity=36.1022364217252, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790207, Length=278, Percent_Identity=32.7338129496403, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17508781, Length=315, Percent_Identity=30.1587301587302, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71991565, Length=322, Percent_Identity=33.2298136645963, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17537387, Length=325, Percent_Identity=28, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322631, Length=311, Percent_Identity=43.7299035369775, Blast_Score=225, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6320930, Length=293, Percent_Identity=36.518771331058, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319788, Length=290, Percent_Identity=24.1379310344828, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355833, Length=330, Percent_Identity=32.1212121212121, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645328, Length=235, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33904; Mature: 33773

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIEMIVAARARLRGHARRTPLLSSPFLNEIAGRRVFVKAECLQHSGSFKFRGGWSAVS
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEHHHHCCCCEEECCCCCHHC
GLDPVIRSKGVIAFSSGNHAQGVALAAKLHNVPSVIIMPSDAPKLKIANTRAFGAEVVLY
CCCHHHHCCCEEEECCCCCCCCEEEEEHHCCCCEEEEECCCCCCEEEECCCCCCEEEEEE
DRVNEDRDEIGARLSAERGLTLIKPFDEPLVIAGQGTTGLEISEQAEEEGVTSAEILVPC
ECCCCCHHHHCCEEHHHCCEEEEECCCCCEEEEECCCCCCEECHHHHHCCCCEEEEEEEE
GGGGLTSGIALALEASAPGFRVRPCEPKDFDDTARSLASGRIERNVAVSGSICDAIVTPQ
CCCCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHCCCCCCEEEECCCHHCEEECCC
PGNITFPILKRLAGAGIVVTDEEALRAMALAFVRLKIVVEPGGAVALAAALFHGEALESD
CCCEEHHHHHHHCCCCEEEECHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCC
TVVVVTSGGNVDSDIFAMALERFG
CEEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ASIEMIVAARARLRGHARRTPLLSSPFLNEIAGRRVFVKAECLQHSGSFKFRGGWSAVS
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEHHHHCCCCEEECCCCCHHC
GLDPVIRSKGVIAFSSGNHAQGVALAAKLHNVPSVIIMPSDAPKLKIANTRAFGAEVVLY
CCCHHHHCCCEEEECCCCCCCCEEEEEHHCCCCEEEEECCCCCCEEEECCCCCCEEEEEE
DRVNEDRDEIGARLSAERGLTLIKPFDEPLVIAGQGTTGLEISEQAEEEGVTSAEILVPC
ECCCCCHHHHCCEEHHHCCEEEEECCCCCEEEEECCCCCCEECHHHHHCCCCEEEEEEEE
GGGGLTSGIALALEASAPGFRVRPCEPKDFDDTARSLASGRIERNVAVSGSICDAIVTPQ
CCCCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHCCCCCCEEEECCCHHCEEECCC
PGNITFPILKRLAGAGIVVTDEEALRAMALAFVRLKIVVEPGGAVALAAALFHGEALESD
CCCEEHHHHHHHCCCCEEEECHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCC
TVVVVTSGGNVDSDIFAMALERFG
CEEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA