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The map label for this gene is yqeC [H]

Identifier: 209550805

GI number: 209550805

Start: 3318070

End: 3319101

Strand: Reverse

Name: yqeC [H]

Synonym: Rleg2_3229

Alternate gene names: 209550805

Gene position: 3319101-3318070 (Counterclockwise)

Preceding gene: 209550806

Following gene: 209550804

Centisome position: 73.14

GC content: 63.08

Gene sequence:

>1032_bases
ATGCAGCTTGGCATGGTTGGTTTGGGCCGCATGGGCAATTACATGGTCCAGCGCCTGATGCGGGGTGGTCACGAATGCGT
CGTTTACGACGCCAGGCCGGAAAGCGTTGCCGAACTCGCAGGCCTCGGTGCGATCGGCAGTGCTTCGCTCGAAGAGTTCG
TCTCGAAGCTCTCGCATCCGCGGGCGATCTGGCTGATGTTGCCGGCGGCGATCGTCGACAAGGTGCTGGCGAACCTGGTG
CCGCTGCTTGAGAATGGCGACATCGTCATCGACGGCGGTAATTCCTATTACCACGACGATATCCGCCGCGGCGCCGACCT
CATCACCAAGGGCATCCACTATGTCGATGTCGGCACAAGCGGCGGCGTGTTCGGCCTGGAGCGCGGTTATTGCCTGATGA
TCGGCGGCGAGAAGGGCACCGTTCAACACCTTTCGCCGATTTTCGCCACACTGGCGCCCGGCGCCGGCGCAACGGAAGCC
TCGCCGAACCGCACCGCCGAAGCGGCTGCGGCGAGCACCGCCGAACAGGGCTACCTGCATTGCGGCCCGCATGGCGCCGG
CCATTTCGTCAAGATGGTGCATAACGGCATCGAATACGGTCTGATGGCCGCCTATGCCGAGGGCATCAACATCCTGAAAC
ACGCCAATATCGGCGCTGCCTCGCATGAGGACGACGCGGAAACCGCGCCGCTTGCCCATCCTGAACATTTTCAATACGAC
TTCAATCTGCAGGACGTCGCCGAAGTCTGGCGCCGCGGCAGCGTCATCACTTCCTGGCTGCTCGATCTGACGGCCGATGC
GCTGCATGCCGATCCGGCGCTGGCGAAATATGCCGGCCGCGTCTCCGACAGCGGCGAAGGCCGCTGGACGATCATGGCGG
CAATCGACGAAAGCGTGCCGACGCCGGTGTTGAGTGCTGCGCTCTACGGCCGTTTCTCTTCGCGCGACAACGACGAATTC
GCCAACAAGGTTCTGTCGGCGATGCGCGCGGGCTTCGGCGGCCACGTGGAAAAACCGGCTCCGAAATCCTGA

Upstream 100 bases:

>100_bases
GTCGCATTCCCCAAGAGCGGCGAGACTTCGCTTGCCTGTCACACTGCGGGTGCTAGTTTCCGGATTCGACACTTCATCTC
GATTTCCAGGAGATTTCATT

Downstream 100 bases:

>100_bases
AGGCCAAGGCGTTCGGCGCCTTCTGGACAAGGAGGCGCCTCAACCTCCCTAGCCATCGGTATGGGGTTCCTACCGCTTGC
TGGCGGCAGCGGTCGCGAGT

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQLGMVGLGRMGNYMVQRLMRGGHECVVYDARPESVAELAGLGAIGSASLEEFVSKLSHPRAIWLMLPAAIVDKVLANLV
PLLENGDIVIDGGNSYYHDDIRRGADLITKGIHYVDVGTSGGVFGLERGYCLMIGGEKGTVQHLSPIFATLAPGAGATEA
SPNRTAEAAAASTAEQGYLHCGPHGAGHFVKMVHNGIEYGLMAAYAEGINILKHANIGAASHEDDAETAPLAHPEHFQYD
FNLQDVAEVWRRGSVITSWLLDLTADALHADPALAKYAGRVSDSGEGRWTIMAAIDESVPTPVLSAALYGRFSSRDNDEF
ANKVLSAMRAGFGGHVEKPAPKS

Sequences:

>Translated_343_residues
MQLGMVGLGRMGNYMVQRLMRGGHECVVYDARPESVAELAGLGAIGSASLEEFVSKLSHPRAIWLMLPAAIVDKVLANLV
PLLENGDIVIDGGNSYYHDDIRRGADLITKGIHYVDVGTSGGVFGLERGYCLMIGGEKGTVQHLSPIFATLAPGAGATEA
SPNRTAEAAAASTAEQGYLHCGPHGAGHFVKMVHNGIEYGLMAAYAEGINILKHANIGAASHEDDAETAPLAHPEHFQYD
FNLQDVAEVWRRGSVITSWLLDLTADALHADPALAKYAGRVSDSGEGRWTIMAAIDESVPTPVLSAALYGRFSSRDNDEF
ANKVLSAMRAGFGGHVEKPAPKS
>Mature_343_residues
MQLGMVGLGRMGNYMVQRLMRGGHECVVYDARPESVAELAGLGAIGSASLEEFVSKLSHPRAIWLMLPAAIVDKVLANLV
PLLENGDIVIDGGNSYYHDDIRRGADLITKGIHYVDVGTSGGVFGLERGYCLMIGGEKGTVQHLSPIFATLAPGAGATEA
SPNRTAEAAAASTAEQGYLHCGPHGAGHFVKMVHNGIEYGLMAAYAEGINILKHANIGAASHEDDAETAPLAHPEHFQYD
FNLQDVAEVWRRGSVITSWLLDLTADALHADPALAKYAGRVSDSGEGRWTIMAAIDESVPTPVLSAALYGRFSSRDNDEF
ANKVLSAMRAGFGGHVEKPAPKS

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=331, Percent_Identity=33.2326283987915, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1788341, Length=343, Percent_Identity=30.9037900874636, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17542558, Length=328, Percent_Identity=32.0121951219512, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6321695, Length=337, Percent_Identity=33.8278931750742, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321977, Length=336, Percent_Identity=33.9285714285714, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24639279, Length=327, Percent_Identity=31.8042813455657, Blast_Score=128, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 36420; Mature: 36420

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00895 3_HYDROXYISOBUT_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGMVGLGRMGNYMVQRLMRGGHECVVYDARPESVAELAGLGAIGSASLEEFVSKLSHP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
RAIWLMLPAAIVDKVLANLVPLLENGDIVIDGGNSYYHDDIRRGADLITKGIHYVDVGTS
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCC
GGVFGLERGYCLMIGGEKGTVQHLSPIFATLAPGAGATEASPNRTAEAAAASTAEQGYLH
CCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEE
CGPHGAGHFVKMVHNGIEYGLMAAYAEGINILKHANIGAASHEDDAETAPLAHPEHFQYD
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEC
FNLQDVAEVWRRGSVITSWLLDLTADALHADPALAKYAGRVSDSGEGRWTIMAAIDESVP
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEECCCCC
TPVLSAALYGRFSSRDNDEFANKVLSAMRAGFGGHVEKPAPKS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQLGMVGLGRMGNYMVQRLMRGGHECVVYDARPESVAELAGLGAIGSASLEEFVSKLSHP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
RAIWLMLPAAIVDKVLANLVPLLENGDIVIDGGNSYYHDDIRRGADLITKGIHYVDVGTS
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCC
GGVFGLERGYCLMIGGEKGTVQHLSPIFATLAPGAGATEASPNRTAEAAAASTAEQGYLH
CCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEE
CGPHGAGHFVKMVHNGIEYGLMAAYAEGINILKHANIGAASHEDDAETAPLAHPEHFQYD
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEC
FNLQDVAEVWRRGSVITSWLLDLTADALHADPALAKYAGRVSDSGEGRWTIMAAIDESVP
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEECCCCC
TPVLSAALYGRFSSRDNDEFANKVLSAMRAGFGGHVEKPAPKS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]